Antiretroviral News and Research

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Facial injections of polylactic acid may help improve loss of fat in the face associated with HIV infection

Facial injections of polylactic acid, a synthetic biodegradable polymer, may help improve the debilitating facial lipoatrophy (loss of fat in the face) associated with HIV infection and its treatment, according to an article in the March issue of Archives of Dermatology.

21 Mar 2006

Cells have a natural defense against HIV

Scientists here have discovered a previously unknown mechanism that cells use to fight off the human immunodeficiency virus (HIV), the cause of AIDS.

14 Mar 2006

Antiretroviral therapy (ART) drugs unlikely to stop HIV spread

Researchers believe antiretroviral therapy (ART) will not be effective in stopping HIV epidemics even if it is made universally available in poorer countries, and that widespread use could even lead to an increase in the numbers infected with HIV.

14 Mar 2006

Completely novel approach to fighting HIV infections

For more than a year, researchers watched patiently as a few computer-simulated HIV protease molecules squirmed into more than 15,000 slightly different shapes. In real time, this contortion takes only a fraction of a second.

13 Mar 2006

Antiretroviral therapy (ART) should be strongly considered in the management of infants infected with HIV

Antiretroviral therapy (ART) for infants born with HIV infection may be most effective when given in their first five months of life, according to a study published in the April 1 issue of The Journal of Infectious Diseases.

9 Mar 2006

Schering-Plough provides update on phase II study of Vicriviroc

Schering-Plough Corporation has provided an update on vicriviroc, its investigational CCR5 receptor antagonist, currently being evaluated by the NIH-sponsored Adult AIDS Clinical Trials Group (ACTG) in an ongoing Phase II clinical study of 118 U.S. treatment-experienced HIV patients.

6 Mar 2006

The incidence, distribution, and control of tuberculosis

A reduction in tuberculosis (TB) incidence, prevalence and death rate can be achieved by 2015 in most parts of the world, with the greatest challenges occurring in Africa and Eastern Europe, according to a projection by the Stop TB Department of the World Health Organization.

1 Mar 2006

HAART is very cost-effective

New research shows that highly active antiretroviral therapy (HAART) is very cost-effective, despite the high price tag. However, the study also shows that reimbursement to physicians treating patients with HIV is critically low, threatening patients' access to care.

1 Mar 2006

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Combining aggressive HIV therapy and chemotherapy significantly improves the survival rates of HIV-positive men and women treated for lymphoma, according to a new study.

27 Feb 2006

HIV testing and counseling reduces high-risk sexual behavior and prevents HIV transmission in Tanzania

Offering free HIV tests instead of charging a small fee is more cost-effective at preventing HIV infections and draws in three times as many people for testing, according to a Duke University Medical Center study conducted in Tanzania.

27 Jan 2006

Bactrim could help HIV-infected children in poor countries

A new systematic review highlights strong results from a single study at the center of mounting support for worldwide use of the low-cost drug Bactrim to help HIV-infected children in poor countries.

25 Jan 2006

Clinton's deal with drug companies will save millions of lives and millions of dollars

Former U.S. President Bill Clinton has struck a deal with nine drug companies to reduce the cost of the second-line AIDS drugs.

16 Jan 2006

Viral 'fitness' explains different resistance patterns to AIDS drugs

Some HIV medications lead to the development of drug-resistant HIV when patients take as few as two percent of their medications. For other medications, resistance occurs only when patients take most of their pills.

10 Jan 2006

Unorthodox vaccine could one day help to prevent or control HIV infection

Researchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection, according to a study published in today's edition of Public Library of Science Medicine.

6 Jan 2006

Nothing changes - AIDS drug goal defeated by bureaucracy

A recent report on the failure of the United Nations "3 by 5" AIDS initiative, says that because of bureaucracy, poor management and inadequate funding, a global drive to put 3 million poor people on life-saving AIDS drugs by the end of 2005, has been defeated.

28 Nov 2005

Zinc supplements shown to be good for children with HIV

According to new research zinc supplements are a safe and effective way to reduce illness in children with HIV.

28 Nov 2005

Zinc supplements safe for chidren with HIV

Zinc-deficient children living in communities where they do not receive adequate amounts of zinc from their diet should be given supplements, even if they are HIV-infected, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions.

26 Nov 2005

United Kingdom has among the highest reported rates of primary resistance to HIV drugs worldwide

Those infected with HIV in the UK have one of the highest rates of resistance to anti-HIV drugs of anywhere in the world, prompting fears of a second wave epidemic of resistant virus, a new study claims in the British Medical Journal (BMJ).

26 Nov 2005

People taking highly active antiretroviral therapy for HIV infection remain susceptible to tuberculosis

...though the risk is lower than for HIV-infected patients not on HAART, according to an article in the Dec. 15 issue of Clinical Infectious Diseases, now available online.

13 Nov 2005

HIV antiretroviral therapy does help those in third world

With preliminary results from a study in Botswana, Harvard School of Public Health researchers have found that people with HIV-1 subtype C in resource-poor settings, who receive antiretroviral (ARV) therapy, can achieve comparable results to those in the developed world.

7 Nov 2005