Antiviral Drug News and Research

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New method to detect fake Tamiflu

Chemists in Georgia are reporting development of a fast new method to detect fake Tamiflu, the mainstay medication for preventing and treating bird flu.

8 Apr 2008

Cancer treatment from a common avian virus under study

Researchers on the Blacksburg and College Park, Maryland campuses of the Virginia-Maryland Regional College of Veterinary Medicine have been awarded a major new grant from the National Institutes of Health (NIH) to support innovative work that seeks to develop a treatment for cancer from a common avian virus.

7 Apr 2008

WHO warns Aussies to prepare for deadly flu

The World Health Organisation (WHO) is warning Australians to prepare for a potentially deadly flu season.

23 Mar 2008

New understanding of Norwalk virus

Using the Canadian Light Source synchrotron, an international team led by University of Calgary researcher Ken Ng has determined the detailed structure of the enzyme the Norwalk virus uses to make copies of its genetic code in order to replicate itself.

20 Mar 2008

NanoBio successfully completes phase 2b study in Herpes labialis

NanoBio Corporation reported top-level findings from its phase 2b study of NB-001, a topical lotion to treat herpes labialis (cold sores).

18 Mar 2008

Investigational drug Debio-025 tested for preventing muscle fiber death in muscular dystrophy

An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).

17 Mar 2008

Study confirms link between colds and ear infections

A new five-year study at the University of Texas Medical Branch at Galveston confirms the suspected close link between the two most common diseases of young children: colds and ear infections.

14 Mar 2008

A simulated pandemic influenza outbreak in Chicago

By using computer simulations and modeling, an international group of researchers including scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech's Network Dynamics and Simulation Science Laboratory (NDSSL) have determined how a pandemic influenza outbreak might travel through a city similar in size to Chicago, Ill.

11 Mar 2008

Pandemic influenza could be mitigated if measures were implemented quickly

An outbreak of pandemic influenza in the U.S. could be mitigated with prompt implementation of social-distancing measures combined with antiviral treatment and prophylaxis until a vaccine is available, according to new findings published in the online Early Edition of PNAS.

10 Mar 2008

Roche on Tamiflu label revision

Roche has informed healthcare professionals that the prescribing information for Tamiflu (oseltamivir phosphate) has been updated to reflect recommendations made by the FDA Pediatric Advisory Committee at a November 27, 2007 meeting regarding neuropsychiatric events.

6 Mar 2008

ISG15 protein inhibits Ebola from reaching out to infect neighboring cells

Scientists at the University of Pennsylvania School of Veterinary Medicine have identified a protein, ISG15, that inhibits the Ebola virus from budding, the process by which viruses escape from cells and spread to infect neighboring cells.

6 Mar 2008

Warning of psychiatric side effects with flu drug Tamiflu

Warnings are being issued concerning the drug Tamiflu by both the drug company Roche and the Food and Drug Administration (FDA) in the U.S.

5 Mar 2008

Serum fibrosis markers correlate with liver fibrosis stage in patients with advanced chronic hep C

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

4 Mar 2008

Gene therapy - immune system discovery may lead to effective treatment for glioblastoma multiforme

A new gene therapy approach that attracts and "trains" immune system cells to destroy deadly brain cancer cells also provides long-term immunity, produces no significant adverse effects and -- in the process of destroying the tumor -- promotes the return of normal brain function and behavioral skills, according to a study conducted by researchers at Cedars-Sinai Medical Center's Board of Governors Gene Therapeutics Research Institute.

20 Feb 2008

Discovery of antibody that neutralizes two viruses classified as henipaviruses

In laboratory experiments, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues supported by the NIH National Institute of Allergy and Infectious Disease (NIAID), have discovered an antibody that neutralizes two viruses classified as henipaviruses.

18 Feb 2008

Amantadine and rimantadine for influenza A in children and the elderly

The antiviral drug amantadine can prevent some cases of influenza in children, and the related medication rimantadine can reduce fever in youngsters who have the flu, according to a new review of evidence.

8 Feb 2008

Chemists track how amantadine drug changes, blocks flu virus

An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists.

5 Feb 2008

Risk factors for severe RSV infection in immunocompromised children

St. Jude Children's Research Hospital investigators and collaborators have shown how to predict if a child who is infected with respiratory syncytial virus (RSV) while being treated for cancer or another catastrophic disease is at high risk for developing severe infection. The finding will help clinicians improve guidelines for managing these infected children.

4 Feb 2008

New anti-HIV medication etravirine shows great promise

The AIDS Institute, a national public policy research, advocacy, and education organization, is encouraged with the FDA's approval of the first new non-nucleoside reverse transcriptase inhibitor (NNRTI) in nearly a decade.

4 Feb 2008

Oseltamivir resistance in European Influenza viruses

Preliminary surveillance into antiviral drug susceptibility against seasonal flu viruses currently circulating in Europe has revealed that some of the A (H1N1) viruses (13%) have shown resistance to the antiviral drug, oseltamivir.

29 Jan 2008