Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Study provides first direct link between plants and humans

The study was published in an advance online edition of the Proceedings of the National Academy of Sciences during the week of April 9, 2007.

10 Apr 2007

Heart muscle cell death is an active and ongoing process in heart failure

Using a nuclear medicine technique and molecular imaging to "see" programmed cell loss, the body's normal way of getting rid of unneeded or abnormal cells, may help in early identification of those individuals who are at risk of developing heart failure, say researchers in the April Journal of Nuclear Medicine.

3 Apr 2007

Preventing cancer without killing cells

Inducing senescence in aged cells may be sufficient to guard against spontaneous cancer development, according to a paper published online this week in EMBO reports.

30 Mar 2007

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Curecumin - potential treatment for lung cancer

Bioponic Phytoceuticals has announced that its Curecumin (a Bioresonant Phytotherapeutic form of Turmeric containing curcumin in a liquid nasal delivery system) may be an important treatment for Lung Cancer.

28 Mar 2007

Study describes how estradiol helps to maintain bone density

Researchers at the University at Buffalo have described a novel pathway by which estradiol, the primary estrogen in humans, aids in maintaining bone density, a function critical to avoiding osteoporosis.

25 Mar 2007

Atorvastatin shows potential as a new treatment for spinal cord injuries

A multidisciplinary investigation led by Inderjit Singh, Ph.D, of the Medical University of South Carolina, has resulted in a new treatment of spinal cord injuries (SCI). The study investigates the efficacy of atorvastatin (AT), (i.e. Lipitor) as a treatment for spinal cord injuries following trauma.

22 Mar 2007

Newly discovered peptide could help transplant for diabetes

A peptide developed by scientists at Weill Cornell Medical College may expand the availability and durability of islet cell transplant for patients with type-1 diabetes, which is characterized by a lack of these insulin-producing cells.

21 Mar 2007

New dimension to understanding of p53 protein

The p53 protein routinely shuts down damaged cells and is one of our main lines of defence against cancer. Scientists at Karolinska Institutet in Sweden now present new findings on how p53 carries out this all-important function.

21 Mar 2007

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

New anti-cancer target in enzyme MAP4K3

Scientists working at the Institute for Cancer Research have found a new anti-cancer target in MAP4K3, an enzyme which is able to 'switch on' the growth-promoter mTOR.

14 Mar 2007

Two novel therapies for multiple myeloma

Two novel biologics are currently being investigated for their potential benefit to multiple myeloma patients in separate ongoing clinical trials at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

14 Mar 2007

Inhaled Celecoxib shows new promise for lung cancer treatment

In recent years, Cycloxygenase (COX)-2 has emerged as a therapeutic target for the prevention and treatment of various types of cancers.

6 Mar 2007

Green tea and COX-2 inhibitors combine to slow growth of prostate cancer

Drinking a nice warm cup of green tea has long been touted for its healthful benefits, both real and anecdotal. But now researchers have found that a component of green tea, combined with low doses of a COX-2 inhibitor, could slow the spread of human prostate cancer.

1 Mar 2007

Scientists alter electrical properties of cells inducing regeneration

Scientists at Forsyth may have moved one step closer to regenerating human spinal cord tissue by artificially inducing a frog tadpole to re-grow its tail at a stage in its development when it is normally impossible. Using a variety of methods including a kind of gene therapy, the scientists altered the electrical properties of cells thus inducing regeneration.

28 Feb 2007

Aspirin offers help for Barrett's esophagus

Researchers at Fred Hutchinson Cancer Research Center have found that people with the most-aggressive form of Barrett's esophagus, a precancerous condition that can lead to esophageal cancer, may benefit the most from preventive therapy with aspirin, ibuprofen and other nonsteroidal anti-inflammatory drugs, or NSAIDs.

27 Feb 2007

New understanding of how and why Taxol works in patients with breast cancer

Cancer researchers at Georgetown University Medical Center have taken a step towards understanding how and why a widely used chemotherapy drug works in patients with breast cancer.

22 Feb 2007

Watercress shows anti-cancer potential

Eating watercress daily can significantly reduce DNA damage to blood cells, which is considered to be an important trigger in the development of cancer, University of Ulster scientists revealed.

18 Feb 2007

HIV protein TAT used to pull protein Bim into cancer cells - helps kill cancer cells

Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around - HIV.

15 Feb 2007

Variation in gene caspase-8 may help protect against breast cancer

A large-scale analysis of data on breast cancer risk has concluded that a common variation in the gene caspase-8 (CASP8) is associated with a somewhat lower risk of the disease. Variants are small changes that occur in a gene sequence.

13 Feb 2007