Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.
In an article published in the June 2017 issue of The Journal of Nuclear Medicine, researchers assert that exposure to medical imaging radiation not only doesn't increase an adult person's risk of getting cancer, it doesn't increase a child's risk.
One of the things that happens to our bodies as we age is that certain cells start to accumulate. So-called senescent cells – cells that "retire" and stop dividing but refuse to die – are always present, and they even serve some important functions, such as in wound repair.
A new study shows that whole tomato extracts from two different Southern Italy cultivars inhibit gastric cancer cell growth and malignant features, paving the way for future studies aimed at implementing lifestyle habits not only for prevention but potentially as a support to conventional therapies.
The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.
Elevated cardiac troponin, a diagnostic marker of damage to the heart, may occur even if a patient has not had a heart attack, according to a study published in JACC: Basic to Translational Science.
Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective.
Researchers from the Cell death group of the Bellvitge Biomedical Research Institute, led by Dr. Cristina Muñoz-Pinedo, have characterized the cell death process due to starvation, in which the endoplasmic reticulum plays a leading role.
Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects.
A SIMPLE eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic -- developed by researchers at University College London and the Western Eye Hospital -- allowed doctors to see individual nerve cell death in the back of the eye.
Johns Hopkins researchers today published new evidence refuting the long-held scientific belief that the gut nerve cells we're born with are the same ones we die with.
In addition to essential metabolic functions, the level of zinc in the body also affects the heart muscle. When oxidative stress occurs, it may be due to a shortage of zinc, which can be determined by examining the heart muscle.
Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.
The stress that some mothers experience during their pregnancies could influence the genetic makeup their babies are born with and, eventually, lead to premature biological ageing and associated age-related diseases.
A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis.
Essen BioScience, a pioneer and leader in the field of cell-based assays and instrumentation used for drug discovery and basic research, has launched the IncuCyte® S3 live-cell analysis platform for real-time, automated measurements of cell health, proliferation, movement and function directly inside a standard incubator.
The study carried out by the Complutense University of Madrid (Spain) –UCM – is the first to evaluate retinal damage using tablets with LED screens available in the market with living animals.
Growth of colorectal cancer cells can be inhibited with the odorant troenan. This is reported by the research team headed by Prof Dr Dr Dr habil. Hanns Hatt and Dr Lea Weber from Ruhr-Universität Bochum in the journal "PLOS One".
MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs.
Peripartum cardiomyopathy (PPCM) occurs globally and is not a disease of the poor, according to research published today in the European Journal of Heart Failure. Cases were reported from many countries for the first time.