Appendix News and Research

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COVID-19 may be linked to acute appendicitis in children

Researchers at the University of Virginia have recently presented a case series pointing to a potential association between infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the development of acute appendicitis in children.

8 Dec 2020

California law banning toxic chemicals in cosmetics will transform industry

A toxic chemical ban signed into law in California will change the composition of cosmetics, shampoos, hair straighteners and other personal care products used by consumers across the country, industry officials and activists say.

23 Nov 2020

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

A team of researchers in Singapore, led by Dr. Joe Yeong, and Prof. Tony Kiat Hon Lim, have reported the presence of residual SARS-CoV-2 ribonucleic acid (RNA) – the virus' genetic material – in stool samples and gastrointestinal tissues from patients recovering from the coronavirus disease 2019 (COVID-19).

8 Nov 2020

Researchers to develop new ultrasound system to help users interpret images

The ultimate aim is to develop an ultrasound machine that all health personnel can use without difficulty.

28 Oct 2020

FDA reissues EUA for certain filtering face-piece respirators manufactured in China

Today, the U.S. Food and Drug Administration (FDA) reissued the Emergency Use Authorization (EUA) for certain filtering face-piece respirators (FFRs) that are manufactured in China and are not approved by the Centers for Disease Control and Prevention's (CDC) National Institute for Occupational Safety and Health (NIOSH).

16 Oct 2020

Antibiotics might be a feasible treatment option for appendicitis, shows study

Henry Ford Health System surgeons involved in the study say patients should choose the best option in consultation with their physician.

6 Oct 2020

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine.

6 Oct 2020

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Seven of 10 adults with appendicitis can safely avoid surgical removal of their appendix (appendectomy) for at least several months by receiving a course of antibiotics, according to early results of a U.S. study that is the largest to compare use of these drugs alone versus an operation for appendicitis treatment.

6 Oct 2020

Study compares antibiotic therapy with surgery in patients with appendicitis

Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to researchers with The University of Texas Health Science Center at Houston, who led the Houston trial sites.

5 Oct 2020

Pregnant women who underwent surgery for complicated appendicitis have significantly better outcomes

Pregnant women who underwent immediate surgery to treat a ruptured or abscessed appendix and their fetuses had significantly better outcomes than those whose condition was managed without an operation.

5 Oct 2020

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefits.

21 Sep 2020

Medical experts emphasize new framework for future efforts to offer specific guidance on right-sizing care

Medical experts have worked for decades to improve the chances that patients will get the scans, routine tests and medicines that can do them the most good - and avoid the ones that won't help them at all.

15 Sep 2020

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

Computed tomography (CT) is used at a higher rate than ultrasound in children with developmental and cognitive impairments to diagnose appendicitis, even though CT scans increase radiation risk in smaller bodies.

21 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

Avoiding care during the pandemic could mean life or death

These days, Los Angeles acting teacher Deryn Warren balances her pain with her fear. She's a bladder cancer patient who broke her wrist in November. She still needs physical therapy for her wrist, and she's months late for a cancer follow-up.

31 Jul 2020

Antibiotics alone can effectively treat children with uncomplicated appendicitis

Appendicitis is the most common cause for emergency abdominal surgery in childhood, affecting 80,000 children in the United States each year, but nonoperative treatment options are viable.

27 Jul 2020

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

A phase 2 trial of an Ad5 vectored COVID-19 vaccine candidate, conducted in China, has found that the vaccine is safe and induces an immune response, according to new research published in The Lancet.

20 Jul 2020

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet.

20 Jul 2020

Lancet issues correction on paper than prompted WHO to suspend Hydroxychloroquine trial

The World Health Organization (WHO) suspended the hydroxychloroquine trial amid the coronavirus pandemic. The decision comes after the study findings published in The Lancet reported issues on the drug's efficacy and safety. Now, the journal has issued a correction on the figures reported in the study.

2 Jun 2020

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

A large observational study suggests that treatment with the antimalarial drug chloroquine or its analog hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19.

22 May 2020

Appendix News and Research

COVID-19 may be linked to acute appendicitis in children

California law banning toxic chemicals in cosmetics will transform industry

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

Researchers to develop new ultrasound system to help users interpret images

FDA reissues EUA for certain filtering face-piece respirators manufactured in China

Antibiotics might be a feasible treatment option for appendicitis, shows study

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Study compares antibiotic therapy with surgery in patients with appendicitis

Pregnant women who underwent surgery for complicated appendicitis have significantly better outcomes

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

Medical experts emphasize new framework for future efforts to offer specific guidance on right-sizing care

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

Avoiding care during the pandemic could mean life or death

Antibiotics alone can effectively treat children with uncomplicated appendicitis

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Lancet issues correction on paper than prompted WHO to suspend Hydroxychloroquine trial

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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