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Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Metrion Biosciences Limited, the specialist ion channel CRO and drug discovery company, and LifeArc, a leading UK independent medical research charity, today announced an extension of their neuroscience-focused ion channel drug discovery collaboration, following the success of the initial twelve-month agreement.

From Metrion Biosciences Limited 4 Dec 2019

Researchers create new technology to help understand how the body battles diseases

Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team of researchers have created new technology to help in understanding how the human body battles diseases.

3 Dec 2019

New findings may help researchers leverage ERAP1 to fight cancer

In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

3 Dec 2019

Study shows potential of hydromethylthionine treatment for Alzheimer's disease

In a paper published in today's online issue of the Journal of Alzheimer's Disease (DOI 10.3233/JAD-190772), TauRx has reported unexpected results of a pharmacokinetic analysis of the relationship between treatment dose, blood levels and pharmacological activity of the drug hydromethylthionine on the brain in over 1,000 patients with mild-to-moderate Alzheimer's disease.

27 Nov 2019

Novel diagnostic method for rapid measurement of celiac disease antibodies

Point-of-care testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is receiving care.

26 Nov 2019

Validation of new method for studying how different drugs interact in the body

Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body.

26 Nov 2019

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

Novoheart, a global stem cell biotechnology company, is pleased to announce a collaboration with global biopharmaceutical company AstraZeneca, in an effort to develop the world’s first human-specific in vitro, functional model of heart failure with preserved ejection fraction (HFpEF), a common condition especially among the elderly and in women, with the reported prevalence approaching 10% in women over the age of 80 years.

26 Nov 2019

Study shows gender differences in prognosis predictive utility of breast cancer recurrence score

The TAILORx study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence according to a genetic assay test.

20 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

CRIPSR could be used to detect disease

CRISPR could be used to establish new diagnostic blood tests by identifying viral nucleic acids, such as Parvo or HPV.

11 Nov 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

Game-changing diagnostic test for prion diseases

Researchers have developed an effective way of testing for prion diseases, a group of fatal neurodegenerative illnesses caused by abnormally folded proteins.

8 Nov 2019

Sartorius publishes third edition of the Live-Cell Analysis Handbook

Sartorius is excited to announce publication of the third edition of our Live-Cell Analysis Handbook, a popular publication for a broad range of scientists who perform cell biology assays as part of their research.

From Sartorius 8 Nov 2019

Discovery of human cell signaling systems using bioinformatics

There are many and various receptors on the surface of each human cell, which bind to specific molecules called ligands, to set off signals that modulate cell activity accordingly. These pathways are exploited by therapeutic drugs. In fact, one in three drugs makes use of receptors belonging to a single very large family – the GPCR (G protein receptor coupled receptor) family.

1 Nov 2019

New BD MAX Check-Points CPO assay receives FDA 510(k) clearance

BD (Becton, Dickinson and Company), a leading global medical technology company, along with Check-Points Health B.V., announced today that FDA 510(k) clearance was obtained for a molecular screening test for antibiotic-resistant carbapenemase-producing organisms on the fully-automated BD MAX System.

From BD (Becton, Dickinson and Company) 30 Oct 2019

New collaborative effort focuses on therapeutic research for CDKL5 Deficiency Disorder

CDKL5 Deficiency Disorder is a devastating neurodevelopmental disorder caused by mutations in the CDKL5 gene.

30 Oct 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

NYU Langone Health launches new molecular assay to identify patients with brain tumors

NYU Langone Health and its Perlmutter Cancer Center have launched clinical whole genome DNA methylation profiling for patients with brain tumors.

24 Oct 2019

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Tuberculosis (TB) causes more deaths in people living with HIV than any other disease, with more than 300,000 deaths in 2017. When detected, early TB can be treated effectively; however, people with advanced HIV are at high risk of death, often without knowing they have TB.

22 Oct 2019

Assay News and Research

Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Researchers create new technology to help understand how the body battles diseases

New findings may help researchers leverage ERAP1 to fight cancer

Study shows potential of hydromethylthionine treatment for Alzheimer's disease

Novel diagnostic method for rapid measurement of celiac disease antibodies

Validation of new method for studying how different drugs interact in the body

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

Study shows gender differences in prognosis predictive utility of breast cancer recurrence score

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Contraceptive drug effective in preventing and regressing cervical cancer in mice

CRIPSR could be used to detect disease

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Game-changing diagnostic test for prion diseases

Sartorius publishes third edition of the Live-Cell Analysis Handbook

Discovery of human cell signaling systems using bioinformatics

New BD MAX Check-Points CPO assay receives FDA 510(k) clearance

New collaborative effort focuses on therapeutic research for CDKL5 Deficiency Disorder

Study finds molecular key to formation of mature and fully functioning T cells

NYU Langone Health launches new molecular assay to identify patients with brain tumors

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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