Astrocyte News and Research

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Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Though drug developers have achieved some progress in treating Alzheimer's disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked.

29 Aug 2023

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

The impacts of physical activity on the neuronal formation and prevent age-related cognitive decay.

22 Aug 2023

Astrocytes play major role in controlling sleep need

New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.

17 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown.

9 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Mathematical model shows how COVID-19 can disrupt brain function

Scientists from Immanuel Kant Baltic Federal University elaborated mathematical model, that imitates the work of neuron networks of brain of patients with COVID -19.

12 Jul 2023

Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

24 Jun 2023

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer scale models will help scientists better understand and study neurodegenerative diseases such as Huntington's disease and schizophrenia.

15 Jun 2023

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Evidence supports a close link between Aβ, astrocyte reactivity, and tau pathology in preclinical AD.

31 May 2023

New research shows astrocytes are key to swaying the pendulum in Alzheimer's disease progression

Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates-;a telltale sign of Alzheimer's brain pathology-;never go on to develop Alzheimer's-associated dementias?

29 May 2023

Astrocyte News and Research

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Could medicinal plants be the key to reversing cognitive decline?

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Astrocytes play major role in controlling sleep need

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

Childhood abuse can induce stress that changes neural networks and functions during growth

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

Can epigenetic changes explain the strong link between age and cancer?

Mathematical model shows how COVID-19 can disrupt brain function

Breakthrough discovery could lead to new treatments for brain metastases

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

New research shows astrocytes are key to swaying the pendulum in Alzheimer's disease progression

Glycosylation enzyme plays a crucial role in brain development, study shows

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers unravel processes that direct the development of astrocyte structure

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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