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FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer's disease.

20 Dec 2023

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and functioning of the central nervous system (CNS) – and multiple sclerosis (MS), a chronic disease in which the body's immune system attacks the CNS and which can produce neurodegeneration.

11 Dec 2023

Study provides a better understanding of how the brain responds to injuries

A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries.

11 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2).

4 Oct 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Though drug developers have achieved some progress in treating Alzheimer's disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked.

29 Aug 2023

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

The impacts of physical activity on the neuronal formation and prevent age-related cognitive decay.

22 Aug 2023

Astrocytes play major role in controlling sleep need

New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.

17 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown.

9 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Astrocyte News and Research

FDA-approved drug may help to decrease pain after surgery, study finds

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

Study provides a better understanding of how the brain responds to injuries

Targeting Alzheimer's with cell-specific genetics

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research explores the unique effects of ADHD medications on Drosophila brain cells

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

The role of exercise-induced hormone irisin in amyloid beta reduction

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Could medicinal plants be the key to reversing cognitive decline?

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Astrocytes play major role in controlling sleep need

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

Childhood abuse can induce stress that changes neural networks and functions during growth

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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