Astrocyte News and Research

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NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Study reveals how astrocytes of socially-isolated mice cause learning and memory deficits

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

14 Feb 2023

What do gut microbiota have to do with Alzheimer's and dementia?

Researchers explore the preventive and therapeutic potential of gut microbiome modulation in the treatment of Alzheimer’s disease.

6 Feb 2023

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

Astrocytes, small star-shaped cells, play an important role in signal transmission in the brain. Since the protein Ezrin is found abundantly in astrocyte tendrils, it is presumed to play a role in brain function.

3 Feb 2023

Schizophrenia may be linked with vascular alterations in the brain, study suggests

A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions.

19 Jan 2023

Researchers develop new tool to isolate and analyze rare astrocyte regulators

Rare cell types can have an undue influence on human health. Previous research has suggested that a subset of astrocytes-;star-shaped cells in the brain and spinal cord-;may be responsible for multiple sclerosis (MS), a disease in which the immune system attacks the covering that protects nerves.

4 Jan 2023

Study provides new insights into the pathology of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes.

16 Dec 2022

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

A new study demonstrated transcriptomic dysregulation in the cerebral cortex in autism spectrum disorder (ASD).

7 Nov 2022

SARS-CoV-2 infections may induce neuroinflammation

Researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on neuroinflammation.

3 Nov 2022

Star-shaped brain cells can "turn off" neurons involved in heroin relapse

Neuroscientists from the Medical University of South Carolina report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin.

5 Oct 2022

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system.

30 Sep 2022

Veterans with PTSD and other psychiatric disorders are at greater risk for early death

Psychiatric symptoms and diagnoses increase risk for premature morbidity and mortality. Now a new study has found that trauma-exposed Veterans with post-traumatic stress disorder and externalizing psychiatric disorders, like substance use disorders and antisocial personality disorder, are at greater risk for early death.

26 Sep 2022

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

A team of researchers at the University of Kentucky's Sanders-Brown Center on Aging has been awarded a $20.5 million grant from the National Institute on Aging of the National Institutes of Health.

2 Sep 2022

Understanding how microglia change their states to adapt to different areas of the brain

In this interview, News Medical speaks to Jeffrey Stogsdill, Ph.D., about his latest research exploring how microglia change their state to adapt to different areas of the brain.

2 Sep 2022

Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body's response to central nervous system (CNS) disorders such as Alzheimer's, Huntington's disease and spinal cord injuries.

2 Jun 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

New therapeutic approach harnesses the body's immune system to protect against brain damage

A therapeutic method for harnessing the body's immune system to protect against brain damage is published today by researchers from the Babraham Institute's Immunology research program.

27 May 2022

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease.

25 May 2022

Astrocyte News and Research

NQO2 gene as a novel potential target in Parkinson’s disease

Study reveals how astrocytes of socially-isolated mice cause learning and memory deficits

What do gut microbiota have to do with Alzheimer's and dementia?

Researchers discover how a protein deficiency can prepare the brain to minimize damage after stress

Schizophrenia may be linked with vascular alterations in the brain, study suggests

Researchers develop new tool to isolate and analyze rare astrocyte regulators

Study provides new insights into the pathology of LATE

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

SARS-CoV-2 infections may induce neuroinflammation

Star-shaped brain cells can "turn off" neurons involved in heroin relapse

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

Veterans with PTSD and other psychiatric disorders are at greater risk for early death

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

Understanding how microglia change their states to adapt to different areas of the brain

Depletion of reactive astrocytes regresses glioblastoma

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

New therapeutic approach harnesses the body's immune system to protect against brain damage

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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