Autoantibodies News and Research

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Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.

3 May 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Researchers investigated the longevity and intensity of the SARS-CoV-2 vaccine immune response in patients suffering from immune-mediated inflammatory diseases.

15 Apr 2022

Dysregulated retroelements associated with autoimmunity in COVID-19

Researchers investigate potential interactions between retro-elements shared between the human and coronavirus genomes.

12 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

Is SARS-CoV-2 a Superantigen?

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), scientists have been conducting extensive studies to understand various aspects of the virus. Researchers have stated that SARS-CoV-2 manifests several biological and clinical consequences of a superantigen

29 Mar 2022

Study evaluates the prevalence of autoantibodies targeting type I interferons in critically-ill COVID-19 patients

Researchers assessed the prevalence of antibodies that neutralize the type I interferon antiviral activity and reactivate herpesviruses such as herpes simplex virus types 1 and 2 and/or cytomegalovirus infections in patients with critical COVID-19.

24 Mar 2022

Bibliographic review evaluates risk of Guillain-Barré syndrome after receiving COVID vaccination

Since the very beginning of the pandemic, there has been concern about the emergence of Guillain-Barré syndrome, a rare disorder where the body's immune system damages nerves. In some cases, nerve damage causes muscle weakness and paralysis.

16 Mar 2022

Researchers identify a potential new test for early diagnosis of Lyme disease

For scientists and clinicians alike, one of the Holy Grails for successfully treating and curing Lyme disease is developing tests that identify the disease sooner, show when people are cured of infection, and can diagnose reinfection.

15 Mar 2022

SARS-CoV-2 in diabetes pathogenesis

Researchers reviewed the causes of diabetes mellitus, focusing on respiratory viruses, including influenza virus and SARS-CoV-2.

15 Mar 2022

How does COVID-19 affect arrythmia?

Researchers have been investigating the reports of cardiac damage in COVID-19 patients, and trying to determine if autoimmune effects could play a role.

10 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Impact of humoral responses in COVID-19

New research discussed the function and impact of humoral immune responses in COVID-19.

7 Mar 2022

Similarities between SARS-CoV-2 and human retroelements explored

A new study investigated the similarities between SARS-CoV-2 and human retroelements.

2 Mar 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Study reveals new way viruses trigger autoimmunity

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems to attack their own bodies.

28 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

A broad evaluation of autoimmune disease-associated autoantibodies that have been observed in COVID-19 patients was performed.

22 Feb 2022