Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Enbrel safety data for up to 8 years in patients with juvenile rheumatoid arthritis

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced the presentation of additional data that showed that the safety profile of Enbrel, (etanercept) was maintained with long-term use in patients with moderate-to-severe juvenile rheumatoid arthritis (JRA) who completed up to eight years of therapy.

17 Jun 2007

What makes people susceptible to rheumatoid arthritis?

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life , the human genome , to figure out what makes these people susceptible to the disabling inflammatory condition.

14 Jun 2007

Researchers successfully treated type 1 diabetic mice with a vaccination

The vaccine they designed in this model included structures that the immune system mistakenly attacks in type 1 diabetes.

28 May 2007

Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid

Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.

24 May 2007

New understanding of how immune-based therapies can treat Alzheimer's disease

24 May 2007

Link between periodontitis and tongue cancer

Researchers at the University at Buffalo and Roswell Park Cancer Institute have shown for the first time that an association exists between long-standing periodontitis, or gum disease, and risk of tongue cancer.

22 May 2007

Genes add up risk of autoimmune disease

Geneticists have identified a link between the number of copies of a specific gene an individual has and their susceptibility to autoimmune diseases like lupus.

22 May 2007

Ulcerative colitis disruptive in relationships

Nearly three out of four ulcerative colitis (UC) sufferers (73 percent) responding to a new nationwide survey say not feeling well has become a normal part of life.

18 May 2007

Natural immune-control system may aid treatment of autoimmune disease and tissue rejection

The immune system's ability to police itself may offer a new method of arresting the cells responsible for autoimmune diseases such as multiple sclerosis and for the rejection of transplanted organs and tissues, scientists at Dana-Farber Cancer Institute report in a study in the May issue of the journal Immunity.

18 May 2007

Methods for treating lupus nephritis

Good patient information is essential for choosing the best treatment for the kidney disease lupus nephritis.

17 May 2007

Complement receptor 3 sends a signal to dampen the immune system

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported that complement receptor 3 (CR3), a protein found on cell surfaces, inhibits dendritic cells, the sentinels of the immune system, from setting off an alarm signal that brings on a full immune response.

16 May 2007

Natural antibodies and tissue injury

Lack of blood flow to the intestines during surgery, to the heart during a heart attack or to the brain during a stroke can cause damage to the organ involved.

15 May 2007

Glucosamine-like dietary supplement suppresses autoimmune response in multiple sclerosis and type-1 diabetes mellitus

This finding shows the potential of using a dietary supplement to help treat autoimmune diseases, said Demetriou, an assistant professor of neurology, and microbiology and molecular genetics.

15 May 2007

Molecule that destroys bone also protects it

An immune system component that is a primary cause of bone destruction and inflammation in autoimmune diseases such as rheumatoid arthritis actually protects bone in the oral cavity from infectious pathogens that play a major role in periodontal disease in humans, research at the University at Buffalo has shown.

7 May 2007

Ultra fast and ultra active: the strange life of the extraocular muscles

The eye, often called the window to the soul, may become a window to the mysteries of muscular dystrophy, a debilitating muscle disease that often leads to death in early adulthood.

2 May 2007

Genetic risk for early death in rheumatoid arthritis

A chronic autoimmune disease, rheumatoid arthritis (RA) is marked by inflammation that takes a progressive toll on not only the joints, but also various organs and the whole body.

30 Apr 2007

World's first microRNA knockout mouse

A role for a microRNA in the immune system has been shown by study of one of the world's first microRNA knockout mouse, reported in Science.

27 Apr 2007

Green tea may help protect against Sjogren's syndrome

They found significantly less salivary gland damage in a group treated with green tea extract, suggesting a reduction of the Sjogren's symptom commonly referred to as dry mouth. Dry mouth can also be caused by certain drugs, radiation and other diseases.

20 Apr 2007

Vitiligo gene linked to other autoimmune diseases

In a study appearing in the March 22 New England Journal of Medicine, scientists supported by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have discovered a connection between a specific gene and the inflammatory skin condition vitiligo, as well as a possible host of autoimmune diseases.

11 Apr 2007

Rep. Dave Weldon comments on stem therapy and type I diabetes

In yet another advance in adult stem cell therapy, the Journal of the American Medical Association (JAMA) today released a study in which 14 of 15 Juvenile Diabetes patients demonstrated significant improvement as a result of an adult stem cell treatment.

11 Apr 2007