Autoimmunity News and Research

RSS

Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Researchers design a probiotic to suppress autoimmunity in the brain

Brigham researchers are working on a new approach to target autoimmunity in the brain leverages designer bacteria to make treatment safer and more effective.

9 Aug 2023

Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Researchers performed a genome-wide association study to explore whether biomarker levels are causally related to COVID-19 hospitalization.

2 Aug 2023

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

Decades of research have left knowledge gaps about cells that regulate the immune system: Purdue and NIH.

1 Aug 2023

Boston College researcher receives grant to study role of gut microbes in Type 1 diabetes

Boston College Assistant Professor of Biology Emrah Altindis has received a two-year, $275,000-grant from the Beatson Foundation to explore the role of gut microbes and viruses triggering the autoimmunity of Type 1 diabetes.

1 Aug 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

m6A modification as a potential therapeutic target for autoimmune diseases

N6-methyladenosine (m6A) is the most extensive studied RNA modification across various species, and the important effect of m6A modification in immune system has been revealed in distinct contexts, including mRNA metabolism, cell differentiation, proliferation and response to stimulation.

14 Jul 2023

DFG funds new clinical research unit to study autoimmune-mediated neurological diseases

How do neurological disorders arise that are caused, triggered, or influenced by antibodies? What better possibilities are there for diagnosis – and above all for treatment? These are the questions addressed by the new Clinical Research Unit "BecauseY" headed by Charité – Universitätsmedizin Berlin. Innovative treatment options will especially benefit patients who at first glance are not suspected of having an antibody-mediated neurological disease.

14 Jul 2023

Study shows potential for treating ALS with two existing drugs

New research suggests that targeting autoimmune inflammation associated with amyotrophic lateral sclerosis (ALS) using two drugs, one of them already approved for multiple sclerosis, could be a promising approach for treatment.

12 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

Early life gut flora may play a role in juvenile idiopathic arthritis

More than ten years before being diagnosed with child rheumatism, children who developed the disease had a gut flora differing in several ways from that of children who remained healthy.

5 Jul 2023

Scientists identify blood proteins that may predict Type 1 diabetes

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

4 Jul 2023

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

Scientists utilized plasma protein proteomics to identify proteins associated with the onset of type 1 diabetes.

3 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

Scientists identify altered proteins that predict islet autoimmunity

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

29 Jun 2023

Measurable upticks in gut bacteria blooms tied to lupus flare-ups

Recurrent bouts of systemic lupus erythematosus, marked by the body's immune system attack of its own tissues, closely tracked with measurable upticks in growth in the gut of a certain species of bacteria.

27 Jun 2023

Study finds link between environmental chemical exposure and thyroid problems in women with fertility issues

A study led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, reveals multiple associations between the presence of phenol biomarkers and altered thyroid hormone measurements among women seeking fertility care.

26 Jun 2023

Research sheds light on how steroids affect cancer Immunotherapy

Immunotherapy is among the newest and most potent weapons against cancer. It prompts the immune system to recognize tumors as intruders in the body and attack. But not all patients respond well to immunotherapy. Why? Scientists aren't always sure.

23 Jun 2023

First successful Phase 2 trial uses cutting-edge RNA CAR-T therapy to treat autoimmunity

Cartesian Therapeutics, a clinical-stage biotechnology company pioneering cell therapies for autoimmune diseases, announced today the publication of a landmark paper in The Lancet Neurology.

22 Jun 2023