Autophagy News and Research

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Autophagy is a normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death. Autophagy may prevent normal cells from developing into cancer cells, but it may also protect cancer cells by destroying anticancer drugs or substances taken up by them.
Study broadens understanding of role of IDH1 and IDH2 mutations in AML

Study broadens understanding of role of IDH1 and IDH2 mutations in AML

New mechanism breaks drug resistance in ovarian cancer

New mechanism breaks drug resistance in ovarian cancer

Agios receives two grants under QTDP program to develop novel cancer metabolism therapies

Agios receives two grants under QTDP program to develop novel cancer metabolism therapies

Alpha-synuclein protein in Parkinson's disease inhibits autophagy: Research

Alpha-synuclein protein in Parkinson's disease inhibits autophagy: Research

Research suggests blocking HMGB1 protein can benefit cancer patients

Research suggests blocking HMGB1 protein can benefit cancer patients

Berries help aging brain stay healthy

Berries help aging brain stay healthy

New study reveals potential role of TGF-β1 in kidney disease

New study reveals potential role of TGF-β1 in kidney disease

Calcium transfer impacts fuel mechanism for normal cell metabolism

Calcium transfer impacts fuel mechanism for normal cell metabolism

Enzyme mTOR regulates autophagy: Study

Enzyme mTOR regulates autophagy: Study

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

Cancer Institute of New Jersey investigators target autophagy

Cancer Institute of New Jersey investigators target autophagy

Roche's xCELLigence System helps study cell viability, cell death while testing cytotoxic compounds

Roche's xCELLigence System helps study cell viability, cell death while testing cytotoxic compounds

CINJ trial targets new combination therapy for advanced solid tumors

CINJ trial targets new combination therapy for advanced solid tumors

The EMBO Meeting 2010: Over 120 researchers to present

The EMBO Meeting 2010: Over 120 researchers to present

Accumulation of mutated protein may explain damaging cellular behavior in Huntington's disease

Accumulation of mutated protein may explain damaging cellular behavior in Huntington's disease

OSU-CG12 agent kills cancer cells through energy restriction: Study

OSU-CG12 agent kills cancer cells through energy restriction: Study

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

Renowned leaders to discuss latest findings in early-stage drug development for cancer

Renowned leaders to discuss latest findings in early-stage drug development for cancer

PINC trial to test anti-malarial drug in women with DCIS

PINC trial to test anti-malarial drug in women with DCIS

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy