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Cocaine use disorder leads to changes in the 'methylome' of a brain region

Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine.

14 Feb 2023

Study reveals how astrocytes of socially-isolated mice cause learning and memory deficits

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

14 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Study indicates that ultra-processed foods are linked to depression

The current paper, published in the journal Nutrients, looks at UPFs in relation to depressive symptoms in a group of younger Italian adults.

14 Feb 2023

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Nutrition researchers at the University of Illinois Chicago studied 80 people with nonalcoholic fatty liver disease and found that those who followed an alternate-day fasting diet and exercised were able to improve their health.

14 Feb 2023

Study could lead to a safe, on-demand and reversible oral contraceptive for men

In a mouse study, researchers funded by the National Institutes of Health have identified a potential non-hormonal contraceptive that men could take shortly before sexual activity and have fertility restored the next day.

14 Feb 2023

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

Ipsen (Euronext: IPN; ADR: IPSEY) today announced three-year minimum, 44-month median, follow-up results from the Phase III CheckMate -9ER trial showing that Cabometyx® (cabozantinib) in combination with nivolumab provides survival and response rate benefits after three-years in the first-line treatment of advanced renal cell carcinoma (aRCC), compared to sunitinib.

From Ipsen 14 Feb 2023

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meetin

Complete Genomics Inc., a global life science tools leader and subsidiary of MGI Tech Co., Ltd. (“MGI”), today launched new revolutionary products and prices at Advances in Genome Biology and Technology (AGBT) General Meeting.

From MGI 14 Feb 2023

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition.

14 Feb 2023

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

A study reveals a previously unknown way in which cannabidiol (CBD), a substance found in cannabis, reduces seizures in many treatment-resistant forms of pediatric epilepsy.

13 Feb 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils.

13 Feb 2023

UT Southwestern researchers map gene control elements responsible for coordinating heartbeats

UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats.

13 Feb 2023

Researchers uncover the cellular basis for sex-specific differences in COVID-19 patients

COVID-19 has had a huge global impact since the initial outbreak in 2019. Men and women show different responses to this disease, with men having a higher risk from infection.

13 Feb 2023

Research details how the circadian and circannual cycles influence humans at the molecular level

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

13 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes.

13 Feb 2023

New method provides important insights into the development of epilepsy

In epilepsy research, it has long been assumed that a leaky blood-brain barrier is a cause of inflammation in the brain.

13 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

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B Cell News and Research

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Study reveals how astrocytes of socially-isolated mice cause learning and memory deficits

New insights into the role of T-cells during long COVID

Study indicates that ultra-processed foods are linked to depression

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Study could lead to a safe, on-demand and reversible oral contraceptive for men

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meetin

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

UT Southwestern researchers map gene control elements responsible for coordinating heartbeats

Researchers uncover the cellular basis for sex-specific differences in COVID-19 patients

Research details how the circadian and circannual cycles influence humans at the molecular level

New analytical platform quantifies the structure of mRNA-based medicines

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

New method provides important insights into the development of epilepsy

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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