Barrett's Esophagus News and Research

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Barrett's Esophagus (BE) is a condition in which the normal lining of the lower part of the esophagus is replaced over time by another type of lining, normally present in the stomach. Usually BE develops during the process of healing after a chronic injury to the esophageal mucosa such as caused by reflux of gastric juice (GERD) in the esophagus. Continued reflux may cause dysplastic changes progressing from Low-Grade to HGD. Such dysplasia may lead to esophageal adenocarcinoma, which is a life-threatening condition. The U.S. National Digestive Diseases Information Clearing House (NDDIC) estimates that the risk of developing adenocarcinoma is 30 to 125 times greater in people who have BE than in people who do not.
Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Index endoscopy results are crucial for assessment of Barrett's patients

Index endoscopy results are crucial for assessment of Barrett's patients

American Gastroenterological Association announces 2019 recipients of annual recognition awards

American Gastroenterological Association announces 2019 recipients of annual recognition awards

New esophageal cancer test uses genetic biomarkers to detect changes in esophagal cells

New esophageal cancer test uses genetic biomarkers to detect changes in esophagal cells

Researchers launch clinical trial to develop breath test for multiple cancers

Researchers launch clinical trial to develop breath test for multiple cancers

Esophageal cancer risk could be reduced by esomeprazole and low dose aspirin

Esophageal cancer risk could be reduced by esomeprazole and low dose aspirin

Centrosome amplification may contribute to initiation of cancers, research suggests

Centrosome amplification may contribute to initiation of cancers, research suggests

New guideline on use of endoscopic eradication therapy in Barrett's esophagus

New guideline on use of endoscopic eradication therapy in Barrett's esophagus

Researchers explore how evolutionary processes guide pathways of cells

Researchers explore how evolutionary processes guide pathways of cells

CUMC researchers discover ‘cell of origin’ for esophageal cancer

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

New studies provide insight into treatments for Barrett's esophagus

New studies provide insight into treatments for Barrett's esophagus

Case Western Reserve University awarded $6 million grant to continue research on Barrett's Esophagus

Case Western Reserve University awarded $6 million grant to continue research on Barrett's Esophagus

AGA creates Obesity Practice Guide for effective weight management in obese patients

AGA creates Obesity Practice Guide for effective weight management in obese patients

Study compares postoperative outcomes, costs of laparoscopic and open antireflux surgery for GERD

Study compares postoperative outcomes, costs of laparoscopic and open antireflux surgery for GERD

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

New method uses computer to scan esophagus images for signs of esophageal cancer

New method uses computer to scan esophagus images for signs of esophageal cancer

Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients

Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients