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BioNanomatrix and Complete Genomics form joint venture after NIST grant awarded

BioNanomatrix, Inc. and Complete Genomics Inc. (CGI) have announced that they have formed a joint venture that has received an $8.8 million grant award from the U.S. National Institute of Standards and Technology Advanced Technology Program (NIST-ATP) to develop a system capable of sequencing the entire human genome in eight hours at a cost of less than $100

29 Sep 2007

New view of what causes greatest genetic variability among individuals

A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals - suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged, or present in extra copies.

27 Sep 2007

Smallpox evolved earlier than believed

Smallpox is older than thought, according to results of a new technique reported in the Sept. 24 issue of the Proceedings of the National Academy of Sciences by researchers from Lawrence Livermore National Laboratory and the Centers for Disease Control (CDC).

27 Sep 2007

New understanding of gene mutation responsible for fragile X syndrome

Scientists have discovered how the gene mutation responsible for fragile X syndrome - the most common inherited form of mental retardation - alters the way brain cells communicate.

18 Sep 2007

JAK genes and cancer

Cancer-causing genes can work in more powerful and sneaky ways than have been realized.

18 Sep 2007

New Rensselaer tools speed stem cell research

Engineers at Rensselaer Polytechnic Institute have developed tools to help solve two of the main problems slowing the progress of stem cell research - how to quickly test stem cell response to different drugs or genes, and how to create a large supply of healthy, viable stem cells to study from only a few available cells.

13 Sep 2007

Ultraconserved elements in the genome: Are they indispensable?

Three years ago, "ultraconserved elements" were discovered in the genomes of mice, rats, and humans.

5 Sep 2007

First individual genome sequence of one person

Independent sequence and assembly of the six billion base pairs from the genome of one person ushers in the era of individualized genomics

4 Sep 2007

Gene regulation in humans is closer than expected to simple organisms

Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc).

30 Aug 2007

New clue to mechanisms of gene signaling and regulation

Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression.

24 Aug 2007

Biologists discover one reason why chromosomes break, often leading to cancer

In the past ten years, researchers in genome stability have observed that many kinds of cancer are associated with areas where human chromosomes break.

6 Aug 2007

Researchers track how a single molecule of RNA or DNA unwinds

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters.

27 Jul 2007

Simple method to comb genomes

Instead of immutable proprietary software, any species, genetic information resembles open source code that is constantly tweaked and optimized to meet the users specific needs.

20 Jul 2007

DNA' s double helix shape explained

Researchers at Duke University's Pratt School of Engineering have uncovered a missing link in scientists' understanding of the physical forces that give DNA its famous double helix shape.

13 Jul 2007

3-D microscopic views of tiny mouse brains available online

A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains - unveiled layer by layer - by extending the capabilities of conventional magnetic resonance imaging.

10 Jul 2007

Neutral genetic drift

Johns Hopkins researchers have added to the growing mound of evidence that many of the genetic bits and pieces that drive evolutionary changes do not confer any advantages or disadvantages to humans or other animals.

10 Jul 2007

Breakthrough new asthma gene found

In a large-scale study conducted with 2,643 children, international researchers with the participation of the Department of Experimental Pneumology of Ruhr-University Bochum (RUB), Germany (Prof. Dr. Albrecht Bufe), have discovered a gene variant that contributes significantly to the risk of childhood asthma.

5 Jul 2007