Beta Blocker News and Research

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Beta-adrenergic receptor blocking agents (beta-blockers) are drugs with multiple actions on the heart. Blockade of beta-1 receptors results in slowing of heart rate, reduction in myocardial contractility, and lowering of systemic blood pressure. In the context of acute myocardial infarction (AMI), which represents a state of reduced oxygen supply to the affected portion of the heart, these effects may be beneficial as they result in reduced myocardial workload and oxygen demand. Furthermore, beta-blockers may reduce the risk of ventricular arrhythmias, which are an important cause of death following AMI.

Study raises concern about the use of beta blockers for all heart patients

Doubt has been cast on the popular practice of giving most heart patients drugs that reduce the heart's workload before and after major surgery, after new research has raised concerns about it.

28 Jul 2005

Eplerenone shows benefit for patients with damaged hearts

In the first thirty days following a heart attack, one in three deaths among patients with signs of heart failure may be preventable by early treatment with a drug called eplerenone (Inspra, Pfizer Ltd), according to new data published in the Journal of the American College of Cardiology (JACC).

26 Jul 2005

Evaluating how hospitals deliver medical care standardizes practices and improves care

In recent years, American hospitals have made significant improvements on standardized, evidence-based measures of clinical performance for several medical conditions, including heart attacks, heart failure, and pneumonia.

20 Jul 2005

Nebivolol may help control high blood pressure

According to research presented at ISHIB2005, nebivolol was shown to be statistically significantly better than placebo in reducing systolic and diastolic blood pressure among African-American hypertensive patients in a multicenter, randomized, double-blind, placebo-controlled study.

18 Jul 2005

Vascular disease most common cause of male erectile dysfunction

A preeminent cardiologist reports, for the first time in a large prospective study, that certain of his patients with erectile dysfunction (ED) and heart problems can now safely use erection drugs that help up to 80% of men restore function and quality of life.

21 Jun 2005

National Service Framework for chronic heart failure is urgently needed

A new National Service Framework for chronic heart failure is urgently needed, because patients with heart failure are getting a raw deal, despite the availability of effective treatment, say leading cardiologists in Heart.

15 Jun 2005

Atrial fibrillation may soon have an effective treatment

In laboratory tests in dogs, cardiac researchers at Washington University School of Medicine in St. Louis have found that treatment with anti-inflammatory drugs after heart surgery may lessen or prevent atrial fibrillation. They report their findings in the June 7 issue of Circulation.

8 Jun 2005

Diabetes knowledge has little effect on improving outcomes

A new study by Duke Clinical Research Institute researchers finds little relationship between what a diabetic patient knows about the disease and control of its associated cardiovascular risk factors or how well the patient ultimately fares.

3 Jun 2005

Under prescribing of statins puts more people at risk of premature death

A new study out of Stanford School of Medicine says that cholesterol-lowering drugs known as statins that can help prevent heart disease are still underprescribed for many at-risk patients.

31 May 2005

A drug that controls blood pressure and reduces heart risk also appears to protect against diabetes

In new results from the VALUE trial that pitted the drug valsartan against another blood pressure drug, amlodipine, the patients taking valsartan were found to have a 23 percent lower risk of developing diabetes during the four or more years of the study.

18 May 2005

Emerging evidence supports early detection, monitoring, and in some cases treatment for children suffering from high blood pressure

One year after recommending that children should be checked for high blood pressure starting at age 3, medical experts reviewed additional supporting evidence for the pediatric blood pressure guidelines at the American Society of Hypertension's Twentieth Annual Meeting (ASH 2005).

16 May 2005

Polypill improves survival rates for heart disease sufferers

A ‘polypill’ made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham.

10 May 2005

Drug combinations improve survival for patients with heart disease

Patients with coronary heart disease who take a combination of three specific drugs have a better chance of survival than those taking single drugs, finds a study in this week's BMJ.

5 May 2005

Survey of ED doctors shows team-based stroke care, risk-reducing measures, needed to increase use of tPA

Forty percent of emergency physicians say they're unlikely to give stroke patients the only FDA-approved drug shown to improve their prognosis, even in an ideal setting, mostly because of the fear of causing brain bleeding.

5 May 2005

New GP contract may not improve treatment for heart failure patients

The new contract for GPs may improve identification and diagnosis of chronic heart failure, but there is a danger that it may fall short of ensuring optimal treatment for these patients, says research published this week in Postgraduate Medical Journal.

4 May 2005

Heart failure patients do better when treated according to guidelines, but too many doctors still fail to prescribe the best treatments

Heart failure patients who are treated in accordance with established European guidelines do better than patients who are not, yet many doctors are still not adhering to the guidelines, according to pioneering research published in Europe’s leading cardiology journal, the European Heart Journal.

4 May 2005

Acupuncture treatment no more effective than sham treatment in reducing migraine headaches

Migraine patients who received true acupuncture had no decrease in headaches as compared with those who received sham acupuncture treatment, according to a study in the May 4 issue of JAMA.

3 May 2005

Antibiotics do not prevent heart attacks

Clinicians and researchers have found that more than three quarters of heart attack patients have been infected with chlamydia pneumoniae - a bacteria found in arteries of heart attack patients - and multiple studies have found this can double the risk of developing subsequent heart attacks.

27 Apr 2005

Genes influence how heart failure patients respond to drugs

Genes dictate the color of our hair and eyes. They factor into whether we get cancer or heart disease. And, scientists increasingly recognize, they also ensure some patients will benefit from a prescription drug, while others develop adverse reactions or simply fail to respond at all.

21 Apr 2005

New technology and treatments for heart and lung patients drive revisions

The process for prioritizing heart and lung transplant candidates and determining the treatments they receive while awaiting donor organs is under review by the International Society for Heart and Lung Transplantation (ISHLT) during its Annual Meeting and Scientific Session this week in Philadelphia.

7 Apr 2005