Bile News and Research

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More objective testing may reduce cost and risk of managing GERD, study suggests

There are significant cost and risk factors associated with two procedures commonly used to diagnose or treat gastrointestinal problems, according to research presented at Digestive Disease Week.

20 May 2013

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Research presented today at Digestive Disease Week explores new discoveries in liver disease research, with findings about the impact of coffee on autoimmune disease and palliative care for cirrhotic patients.

20 May 2013

Boston Scientific presents data on breakthrough products at Digestive Disease Week 2013

Boston Scientific Corporation is scheduled to participate in Digestive Disease Week 2013, May 18-21 in Orlando, Fla.

20 May 2013

Study: Biologic response modifying drugs can cause acute liver injury

A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

30 Apr 2013

Urine tests could improve diagnosis of liver cancer

New data from two clinical trials presented today at the International Liver Congress- 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic urine tests.

26 Apr 2013

Genetic study defines link between primary sclerosing cholangitis and other autoimmune diseases

Researchers have newly associated nine genetic regions with a rare autoimmune disease of the liver known as primary sclerosing cholangitis (PSC). This brings the total number of genetic regions associated with the disease to 16.

22 Apr 2013

Research shows certain cells take on new identities through reprogramming mechanism

Researchers have been able to reprogram cells experimentally, but few have shown that cells can change their identities under normal physiological conditions in the body, particularly in mammals.

29 Mar 2013

Blocked bile ducts can be effectively treated with metal stents

A multi-center analysis, led by Weill Cornell Medical College and published in the Journal of Clinical Gastroenterology, shows the use of temporary "fully covered self-expanding metal stents" (FCSEMS) can effectively fix a painful and potentially life-threatening benign biliary stricture -- a severely blocked or narrowed bile duct.

21 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

Donor liver quality: an interview with Dr Eric Orman

Liver transplantation is a surgical procedure in which a liver (or part of a liver) is removed from a donor and placed into a recipient. Although some transplants use a portion of the liver of living donors, the vast majority of donors are deceased.

6 Feb 2013

Antibiotics produce changes in microbial and metabolic patterns of the gut

A study co-led by researchers at the Universitat de València reveals that antibiotics produce changes in the microbial and metabolic patterns of the gut.

9 Jan 2013

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of a $1.7 million grant from the National Cancer Institute to study the behavior of a parasitic worm, rampant in Southeast Asia, known to cause infections that contribute to liver cancer.

16 Nov 2012

Biliary sludge common in dogs

Biliary sludge occurs in around a third of dogs, most often in senior animals, and with no difference in frequency between males and females, shows analysis of ultrasonography data for more than 1000 animals.

14 Nov 2012

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

Albireo AB, a biopharmaceutical company specializing in gastroenterology, today announced that A4250 (an inhibitor of the ileal bile acid transporter, IBAT/ASBT) has been granted orphan-drug designation by the U.S Food and Drug Administration for the treatment of Progressive Familial Intrahepatic Cholestasis (PFIC) and Primary Biliary Cirrhosis (PBC).

8 Nov 2012

Probiotic formulation can reduce cholesterol esters

Two daily doses of a probiotic lowered key cholesterol-bearing molecules in the blood as well as "bad" and total cholesterol, in a study presented at the American Heart Association's Scientific Sessions 2012.

6 Nov 2012

Cholangiography use endorsed in cholecystectomy

Bile duct injury significantly impairs survival after cholecystectomy, particularly when it goes undetected during surgery, show the results of a study published in the BMJ.

25 Oct 2012

Patients with chronic constipation at increased risk of colorectal cancer, benign neoplasms

Patients with chronic constipation may be at increased risk of developing colorectal cancer and benign neoplasms, according to study findings unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

22 Oct 2012

Researchers identify three genetic regions associated with primary biliary cirrhosis

Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the disorder to 25.

10 Sep 2012

Children with obesity face increased risk for gallstones

Children who are overweight or obese face an increased risk for gallstones, according to a Kaiser Permanente study published in the Journal of Pediatric Gastroenterology & Nutrition.

26 Aug 2012

Bile News and Research

More objective testing may reduce cost and risk of managing GERD, study suggests

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Boston Scientific presents data on breakthrough products at Digestive Disease Week 2013

Study: Biologic response modifying drugs can cause acute liver injury

Urine tests could improve diagnosis of liver cancer

Genetic study defines link between primary sclerosing cholangitis and other autoimmune diseases

Research shows certain cells take on new identities through reprogramming mechanism

Blocked bile ducts can be effectively treated with metal stents

Stem cell line could also advance research into liver cancers, cystic fibrosis

Cholesterol metabolism regulated by bacteria in the small intestine

Donor liver quality: an interview with Dr Eric Orman

Antibiotics produce changes in microbial and metabolic patterns of the gut

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Biliary sludge common in dogs

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

Probiotic formulation can reduce cholesterol esters

Cholangiography use endorsed in cholecystectomy

Patients with chronic constipation at increased risk of colorectal cancer, benign neoplasms

Researchers identify three genetic regions associated with primary biliary cirrhosis

Children with obesity face increased risk for gallstones

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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