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Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

What effect do nuts have on gastrointestinal health?

Researchers presented an overview of the latest research on the impact of nut intake on gastrointestinal health.

4 Apr 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence.

14 Mar 2023

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Dementia with Lewy bodies (DLB), one of the most common forms of dementia, has no cure. Previous studies suggested that gut bacteria, the microorganisms that live in the human digestive tract, play a role in Parkinson's disease, another neurodegenerative disorder, but the bacteria involved in DLB had not been identified.

28 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

Effects of nanoparticles on gouty arthritis in animal models of gout

Researchers performed a systematic review and meta-analysis to explore the effects of nanoparticles on gouty arthritis using animal models.

23 Feb 2023

How the human gut microbiota is shaped by diet

A new study in the journal Best Practice & Research Clinical Gastroenterology aimed to summarize the impact of specific nutrients as well as diets on the gut microbiota as well as the future perspectives of using diet as a therapeutic microbiome modulator.

20 Feb 2023

Bile News and Research

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

Interplay between Western diet, gut microbiota, and cancer development

What effect do nuts have on gastrointestinal health?

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Age and sex determine the effects of microbiota on mice's metabolome

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

The burden of Clostridioides difficile infections in the United States

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Effects of nanoparticles on gouty arthritis in animal models of gout

How the human gut microbiota is shaped by diet

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

New insights on bile duct and gallbladder cancers

Protein adduction and p53 tumor suppressor inhibition

Transient gut infection influences hosts’ adaptation to nutrient restriction

Incurable liver disease could be reversed with a single drug

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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