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New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Researchers quantified the residues of eight neonicotinoids in human bile samples to understand the association between internal neonicotinoid exposure and hepatotoxic outcomes.

4 Jan 2023

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients."

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

How the COVID-19 pandemic impacted the treatment pancreatic cancer patients

Researchers investigates the impact of the COVID-19 pandemic on pancreatic cancer services in England.

11 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Study provide new insights into why cholestasis causes cognitive issues

Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline.

6 Dec 2022

The separate and combined associations of coffee and tea consumption with all-cause and cause-specific mortality

Researchers investigated the association between individual and combined coffee and tea consumption and all-cause and cause-specific mortality, such as those due to cardiovascular, respiratory, and digestive diseases.

22 Nov 2022

Parasites associated with leprosy may have the ability to regenerate livers

Leprosy is one of the world's oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ.

15 Nov 2022

Metabolomic study of genetic regulation of biochemical individuality

Researchers systematically investigated the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites.

15 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

CT and MRI scans fail to detect many pancreatic cancer cases, study reveals

Pancreatic cancer tumors are being missed on CT and MRI scans, narrowing the window for life-saving curative surgery, research presented today at UEG Week 2022 has revealed.

11 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

Bile acids play an important role in regulating gut microbiome

Scientists performe in vitro and in vivo experiments to investigate the antimicrobial effects of different bile acids on various microorganisms.

27 Sep 2022

Consumption of highly refined fiber may increase liver cancer risk in some people

Many people commonly consume fiber-enriched foods to promote weight loss and prevent chronic diseases such as diabetes and cancer.

26 Sep 2022

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

When fat accumulates in the liver, the immune system may assault the organ. A new study from Weill Cornell Medicine researchers identifies the molecule that trips these defenses, a discovery that helps to explain the dynamics underlying liver damage that can accompany type 2 diabetes and obesity.

19 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Smoking continues to be a leading cause of cancer-related death

A new study led by researchers at the American Cancer Society (ACS) reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.