Biochemistry News and Research

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Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Researchers at the University of Texas Medical Branch at Galveston and the University of California-San Diego School of Medicine have published a study that offers a new understanding of a protein critical to physiological processes involved in major diseases such as diabetes and cancer. This work could help scientists design drugs to battle these disorders.

18 May 2011

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development of leukemia also acts to prevent cancer of the liver.

17 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

Computationally designed antiviral proteins may fight against influenza

A research article May 12 in Science demonstrates the use of computational methods to design new antiviral proteins not found in nature, but capable of targeting specific surfaces of flu virus molecules.

16 May 2011

McGill research team finds distinct disease-causing mutations and saves baby girl

About two years ago, Dr. Philippe Gros, a McGill University professor in the Department of Biochemistry and a Principal Investigator in thd McGill Life Sciences Complex, described a mouse mutant that was immunodeficient and hypersensitive to the Bacille Calmette-Gu-rin (BCG) vaccine and to tuberculosis (TB).

12 May 2011

Researchers help explain why smart drugs are not effective in some cancer patients

Some of the most effective and expensive cancer drugs, dubbed "smart drugs" for their ability to stop tumors by targeting key drivers of cancer cell growth, are not effective in some patients. In two related studies, Yale School of Medicine researchers examined one such driver, the EGF receptor, and found that a decoy receptor might be limiting the amount of drug that gets to the intended target.

12 May 2011

Novel two-drug combination cures young patient with extensively drug-resistant tuberculosis

Belgian physicians report they have cured a young patient with extensively drug-resistant tuberculosis (XDR-TB) using a novel two-drug combination developed by researchers at Albert Einstein College of Medicine of Yeshiva University. The report, published in the Pediatric Infectious Disease Journal, marks the first known clinical use of this treatment for XDR-TB, the most deadly form of the disease.

11 May 2011

Long non-coding RNA promotes melanoma cell survival and invasion

Traditionally, RNA was mostly known as the messenger molecule that carries protein-making instructions from a cell's nucleus to the cytoplasm. But scientists now estimate that approximately 97 percent of human RNA doesn't actually code for proteins at all. A flurry of research in the past decade has revealed that some types of non-coding RNAs switch genes on and off and influence protein function.

11 May 2011

UH chemist receives prestigious Sloan award for next-generation computer memory

Investigating the building blocks for next-generation computer memory has earned a University of Houston chemist his third Tier One research award.

10 May 2011

Scientists decipher genome of tropical marine organism

An international team of researchers led by scientists at Scripps Institution of Oceanography at UC San Diego has deciphered the genome of a tropical marine organism known to produce substances potentially useful against human diseases.

10 May 2011

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Three UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their investigations of treatment strategies for degenerative muscle diseases, such as muscular dystrophy, and heart disease, and to determine why human embryonic stem cells are susceptible to forming tumors.

10 May 2011

Cancer researchers help unlock cellular-level function of telomerase enzyme

Cancer researchers at UT Southwestern Medical Center are helping unlock the cellular-level function of the telomerase enzyme, which is linked to the disease's growth.

7 May 2011

BUSM research shows how heparan sulfate interacts with growth factor proteins

When the human genome project produced a map of human genes, the number of genes in humans turned out to be relatively small, approximately the same number as in primitive nematode worms.

5 May 2011

UCSF scientists elected as members of National Academy of Sciences for excellence in biomedical research

Alexander D. Johnson, PhD, and Shinya Yamanaka, MD, PhD, have been elected as members of the National Academy of Sciences for their excellence in original scientific research. It is one of the highest honors bestowed on a scientist or engineer in the United States.

5 May 2011

Researchers identify regulatory protein that can inhibit cancer metastasis

A protein capable of halting the spread of breast cancer cells could lead to a therapy for preventing or limiting the spread of the disease.

5 May 2011

New non-invasive blood test may detect early stage Alzheimer's

A new blood test that will diagnose Alzheimer's disease may soon hit the market, thanks to an innovative study from the Research Institute of the McGill University Health Centre.

4 May 2011

New book on the myth of junk DNA

Forty years ago scientists discovered that more than 95% of our DNA does not encode proteins. Since then the non-protein-coding portion was labeled "junk" and attributed to molecular accidents that have accumulated in the course of evolution.

4 May 2011

New nano-vault delivery system can fight cancer

UCLA scientists have discovered a way to wake up the immune system to fight cancer by delivering an immune system-stimulating protein in a nanoscale container called a vault directly into lung cancer tumors, harnessing the body's natural defenses to fight disease growth.

4 May 2011

Affinium announces AFN-1252 Phase I study results in staphylococcal infections

Affinium Pharmaceuticals announced today the results of a new multiple ascending dose Phase I study of its novel, selective-spectrum, anti-staphylococcal agent, AFN-1252 in a novel oral formulation.

3 May 2011

Biochemistry News and Research

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Over-activation of single gene promotes leukemia, but its loss causes liver cancer

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Computationally designed antiviral proteins may fight against influenza

McGill research team finds distinct disease-causing mutations and saves baby girl

Researchers help explain why smart drugs are not effective in some cancer patients

Novel two-drug combination cures young patient with extensively drug-resistant tuberculosis

Long non-coding RNA promotes melanoma cell survival and invasion

UH chemist receives prestigious Sloan award for next-generation computer memory

Scientists decipher genome of tropical marine organism

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Cancer researchers help unlock cellular-level function of telomerase enzyme

BUSM research shows how heparan sulfate interacts with growth factor proteins

UCSF scientists elected as members of National Academy of Sciences for excellence in biomedical research

Researchers identify regulatory protein that can inhibit cancer metastasis

New non-invasive blood test may detect early stage Alzheimer's

New book on the myth of junk DNA

New nano-vault delivery system can fight cancer

Affinium announces AFN-1252 Phase I study results in staphylococcal infections

Biochemistry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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