Biochemistry News and Research

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Scientists manipulate simple bacteria into constructing internal compartments for biofuels, vaccines

Scientists at the University of Kent and University College Cork have manipulated simple bacteria into constructing internal compartments where biofuels and vaccines can be produced.

14 Jun 2010

Cellular response plays a key role in wound healing

Researchers from the University of Illinois at Chicago have discovered that an unexpected cellular response plays an important role in breaking down and inhibiting the formation of excess scar tissue in wound healing.

11 Jun 2010

Pfizer to join SGC-led collaboration to generate chemical probes for proteins involved in epigenetic signalling

The Structural Genomics Consortium (SGC) and Pfizer today announced that Pfizer will join the SGC-led public-private collaboration to generate small molecule inhibitors - "chemical probes" - for proteins involved in epigenetic signalling.

11 Jun 2010

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

The p53 gene has been a well-documented player in the prevention of tumors. It is considered the most frequently mutated gene in human tumors with more than half harboring p53 mutations (Bennett et al., 1999). These mutations often can be caused by disruption in normal p53 function.

11 Jun 2010

Texas Tech signs worldwide license agreement for metallo-beta-lactamase inhibitors with RI Scientific

Officials at Texas Tech University System's Office of Technology Commercialization announced Wednesday (June 9) the signing of an exclusive worldwide license agreement for a chemical additive called an aptamer that makes certain existing antibiotics viable against antibiotic-resistant bacteria.

10 Jun 2010

New findings may help researchers design drugs that can prevent HIV

Researchers at the University of Iowa Carver College of Medicine and University of Nebraska Medical Center have created a three-dimensional picture of an important protein that is involved in how HIV -- the virus responsible for AIDS -- is produced inside human cells. The picture may help researchers design drugs that can prevent HIV from reproducing.

10 Jun 2010

Princeton University president named 2010 winner of Henry G. Friesen International Prize in Health Research

Internationally renowned scientist and scholar Shirley M. Tilghman, president of Princeton University, was named the 2010 winner of the Henry G. Friesen International Prize in Health Research.

8 Jun 2010

Tel Aviv University discovers ancient switch in plants that could halt cancer metastasis

Although plants and animals are very different organisms, they share a surprising number of biological mechanisms. A plant biologist at Tel Aviv University says that one of these mechanisms may be the answer for turning off cancer growth in humans.

8 Jun 2010

Data shows VB-201 controls inflammatory responses associated with autoimmune diseases, atherosclerosis

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced preclinical data demonstrating that VB-201 regulates inflammatory pathways, suggesting that it may effectively control inflammatory responses associated with autoimmune diseases and atherosclerosis.

7 Jun 2010

McMaster University researchers discover chemical clue directing Staphylococcus aureus

McMaster University researchers have discovered a central controller or processing unit of a superbug's weaponry. An article on the breakthrough appears in the high-impact journal Science today.

4 Jun 2010

Researchers develop new technique to detect cathepsin K in atherosclerosis, cancer metastasis

An enzyme implicated in osteoporosis, arthritis, atherosclerosis and cancer metastasis -- cathepsin K -- eluded reliable detection in laboratory experiments in the past. Now, a research team at the Georgia Institute of Technology has developed an assay that reliably detects and quantifies mature cathepsin K using a technique called gelatin zymography.

2 Jun 2010

Constellation Pharmaceuticals raises $22 million in Series B financing round

Constellation Pharmaceuticals, Inc., the leading biopharmaceutical company focused on discovering and developing new drugs targeting epigenetic regulation of the human genome, today announced that it has raised $22 million in a Series B financing round.

2 Jun 2010

Predictive biomarker for patients with NSCLC

The era of one-size-fits-all medicine will eventually be history; after all it is no news that drugs and treatments do not work the same for everyone. For patients with nonsmall cell lung cancer, a lung cancer that kills approximately 1 million people annually, the treatment currently available is basically the same for all patients, despite the fact that some patients may respond to treatment while others may not.

2 Jun 2010

UCI study provides blueprint for enhanced treatment of inflammatory diseases

By discovering how adult neural stem cells navigate to injury sites in the central nervous system, UC Irvine researchers have helped solve a puzzle in the creation of stem cell-based treatments: How do these cells know where to go? Tom Lane and Kevin Carbajal of the Sue and Bill Gross Stem Cell Research Center found the answer with the body's immune system.

2 Jun 2010

CCL5 protein plays protective role against Mycobacterium tuberculosis: New research

Ohio scientists hope to counter the re-emerging threat of tuberculosis with help from proteins from our bodies. In a research report published in the June 2010 print issue of the Journal of Leukocyte Biology, scientists show how the protein CCL5 plays a protective role in helping the body ward off this contagious, airborne disease in the early stages of infection.

2 Jun 2010

New model reveals molecular basis of multiple hereditary exostoses

Children born with multiple hereditary exostoses (MHE) suffer from abnormal growths on their bones. These bony protrusions stunt their growth and can cause pain and disfigurement.

2 Jun 2010

Free online seminars on Reaction Progress Kinetic Analysis

Reaction Progress Kinetic Analysis (RPKA) streamlines kinetic studies by exploiting extensive data available from accurate in situ monitoring of global reaction progress under synthetically relevant conditions, where the concentrations of two or more reactants are changing simultaneously – in fact, in the same manner that they are expected to change during practical synthesis.

31 May 2010

Yeast produce a hormone that triggers fungal cells to become more infectious

In their ongoing studies of how yeast (fungi) can infect a host and cause disease, a research team at the Life Sciences and Bioengineering Center at Worcester Polytechnic Institute (WPI) has made an unexpected discovery. They found that yeast produce a hormone previously known to be made by plants, and that the presence of that hormone in sufficient quantity within the yeast's immediate environment triggers the fungal cells to become more infectious.

29 May 2010

Discovery may pave way to help reduce health hazards

A discovery that may pave the way to helping reduce health hazards such as E. coli in water could also make chemicals and drugs such as insulin cheaper to produce and their production more environmentally friendly.

28 May 2010

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions.

28 May 2010

Biochemistry News and Research

Scientists manipulate simple bacteria into constructing internal compartments for biofuels, vaccines

Cellular response plays a key role in wound healing

Pfizer to join SGC-led collaboration to generate chemical probes for proteins involved in epigenetic signalling

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

Texas Tech signs worldwide license agreement for metallo-beta-lactamase inhibitors with RI Scientific

New findings may help researchers design drugs that can prevent HIV

Princeton University president named 2010 winner of Henry G. Friesen International Prize in Health Research

Tel Aviv University discovers ancient switch in plants that could halt cancer metastasis

Data shows VB-201 controls inflammatory responses associated with autoimmune diseases, atherosclerosis

McMaster University researchers discover chemical clue directing Staphylococcus aureus

Researchers develop new technique to detect cathepsin K in atherosclerosis, cancer metastasis

Constellation Pharmaceuticals raises $22 million in Series B financing round

Predictive biomarker for patients with NSCLC

UCI study provides blueprint for enhanced treatment of inflammatory diseases

CCL5 protein plays protective role against Mycobacterium tuberculosis: New research

New model reveals molecular basis of multiple hereditary exostoses

Free online seminars on Reaction Progress Kinetic Analysis

Yeast produce a hormone that triggers fungal cells to become more infectious

Discovery may pave way to help reduce health hazards

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

Biochemistry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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