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$Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair$

Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair

Screening for even mild depressive symptoms before hip fracture repair may be helpful in predicting which patients are at higher risk of developing delirium after emergency surgery, according to results of a new study by researchers from Johns Hopkins Medicine.

4 May 2021

Social cognition may exert a central role in the daily lives of MS patients

An international team of multiple sclerosis (MS) researchers showed that longitudinal changes in social cognition are associated with psychological outcomes of daily living, suggesting that social cognition may exert a central role in people with MS.

3 May 2021

People with multiple sclerosis experience subtle language impairments, study shows

Kessler Foundation researchers showed that people with multiple sclerosis (MS) experience subtle language impairments that standard neuropsychological tests may incorrectly attribute to impaired executive functions.

22 Apr 2021

Memory and executive function symptoms are valuable for predicting CTE pathology, suggests study

Diagnosing Chronic Traumatic Encephalopathy (CTE) during life is crucial for developing therapies and for determining how common the disease is among individuals exposed to repetitive head impacts from contact sports, military service and physical violence.

7 Apr 2021

Study: Alzheimer's disease treatments could reduce the financial burden to U.S. state budgets

Alzheimer's disease treatments that slow progression of the disease could significantly reduce the financial burden to U.S. state budgets, according to a new USC study.

5 Apr 2021

Researchers test novel gene regulation approach to treat brain diseases

Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies.

22 Mar 2021

New project to investigate a promising drug target for treatment of schizophrenia

A partnership between the University of Oxford, Earlham Institute (EI), and global pharmaceutical companies Biogen Inc and Boehringer Ingelheim will investigate a promising new drug target for the treatment of schizophrenia.

22 Jan 2021

Researchers receive $651,997 funding to study memory dysfunction in MS

Researchers at Montclair State University and Kessler Foundation have received funding totaling $651,997 from the National Multiple Sclerosis Society to measure memory-related abilities in individuals with and without multiple sclerosis (MS) for clues to how such cognitive processes are altered by MS. Joshua Sandry, PhD, assistant professor of psychology at Montclair State and Ekaterina Dobryakova, PhD, research scientist in the Center for Traumatic Brain Injury Research at Kessler Foundation, collaborate on the 4-year study, titled "Neuroimaging of Hippocampally Mediated Memory Dysfunction in Multiple Sclerosis."

10 Dec 2020

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

A team of researchers recently investigated the genetic determinants of COVID-19 risk and severity in humans.

6 Nov 2020

Study identifies determinants of unemployment in individuals with multiple sclerosis

Lauren Strober, PhD, at Kessler Foundation recently published results of the first prospective study of employment and multiple sclerosis (MS).

5 Oct 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

Scientists reconstruct factors involved in the formation of autophagosomes

Autophagy, from the Greek for 'self-eating', is an essential process that isolates and recycles cellular components under conditions of stress or when resources are limited.

4 Sep 2020

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology.

3 Sep 2020

Trinity College researchers to participate in gene-based clinical trial for motor neuron disease

Researchers at Trinity College Dublin are to participate in an early phase gene-based clinical trial for motor neuron disease (MND). The research team represents one of only four centres in Europe to take part in such an exciting clinical trial for this devastating disease.

2 Sep 2020

A powerful tool for separation and sizing of virus mixtures

Postnova Analytics has published an applications report that presents data from a collaboration with the Analytical Development group at Biogen Inc. on separation of a virus mixture using Asymmetrical Flow Field-Flow Fractionation and measurement of their radius of gyration.

From Postnova Analytics 27 Aug 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children.

1 Jul 2020

Newly discovered Alzheimer's gene may drive earliest brain changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers at Columbia University Irving Medical Center.

22 Jun 2020

Case series: COVID-19 in teriflunomide-treated patients with MS

During the COVID-19 pandemic, patients with multiple sclerosis (MS) and their clinicians have had questions and concerns about whether immunotherapies for MS could influence risk for infection or lead to an unfavorable outcome.

12 Jun 2020

New digital tool to support mental health of MS patients developed with UK HCPs

Biogen Inc. today announced the launch of a free, new, digital self-help tool to help people living with multiple sclerosis (MS) navigate the emotional challenges of life with the disease. The tool, named ACT MySelf, was developed by Biogen in collaboration with people living with MS, the MS Trust, a team of MS specialist nurses and an MS clinical psychologist.

5 Jun 2020