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Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.

29 May 2020

Discovery of T cells response spectrum could new shed light on immune diseases

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer, and what goes wrong in immune diseases.

15 Apr 2020

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Older adults who have surgery with general anesthesia may experience a modest acceleration of cognitive decline, even years later. But there's no evidence of a link to Alzheimer's disease, according to new research from Mayo Clinic.

12 Mar 2020

Widowed individuals experience a sharper cognitive decline than their married counterparts

The death of a spouse often means the loss of intimacy, companionship and everyday support for older adults.

26 Feb 2020

New multi-sensor tool quickly measures subtle changes in MS patients

Multiple sclerosis (MS) is a progressive, chronic disorder in which the body's immune system attacks the central nervous system, resulting in multiple adverse effects, from numbness, fatigue and impaired speech to loss of muscle control and vision.

26 Feb 2020

Genome research collaboration in Finland welcomes Janssen and Maze Therapeutics

FinnGen, a large-scale academic - industry, genome research collaboration in Finland now includes eleven industry partners with the addition of the Janssen Pharmaceutical Companies of Johnson & Johnson and Maze Therapeutics.

25 Feb 2020

Spanish version of modified Story Memory Technique effective for Mexicans with MS

A team of researchers reported preliminary findings for efficacy of the Spanish version of the modified Story Memory Technique, a cognitive intervention developed at Kessler Foundation.

19 Feb 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

Overactivation of neuroimmune gene leads to schizophrenia-like changes in mice

Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal PLOS Biology by Ashley Comer and Alberto Cruz-Martín of Boston University and colleagues.

14 Jan 2020

Prospective memory associated with performance of everyday life activities in MS patients

Kessler Foundation researchers reported results of a study of deficits in prospective memory in individuals with multiple sclerosis (MS) that may contribute to difficulties with everyday life activities.

22 Dec 2019

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

First large-scale study to quantify gender differences in language framing in biomedical research

Perception is reality, the adage goes, and it may even be true when it comes to conveying the findings of medical and life science research.

17 Dec 2019

Researchers identify factors impacting money management skills in MS patients

A team of rehabilitation researchers identified factors associated with the money management problems experienced by some individuals with multiple sclerosis.

17 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

Study underscores the influence of sensory processing in multiple sclerosis

A team of researchers published new findings about the role of sensory processing and disease characteristics in the functional status of individuals with multiple sclerosis.

22 Nov 2019

Investigational drug for treating patients with treatment-resistant epilepsy

Imagine not being able to drive, shower alone or even work because you are never quite sure when the next seizure will leave you incapacitated.

21 Nov 2019

Australia has limited capacity to move future Alzheimer's therapy into wide clinical use

As in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from approval into wide clinical use, which could leave thousands of older people without access to transformative care if such a breakthrough occurs, according to a new study by RAND Australia.

11 Nov 2019