Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

A systems biology map of iron metabolism

Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism.

30 Apr 2009

Study findings have implications for development of pain-relieving drugs

Morphine and other opioids are widely used to treat both acute and chronic pain – yet their benefits are often limited because some people experience side effects or do not respond to them efficiently.

21 Apr 2009

New insights into transcription factors in human cells

Bioinformatics researchers from UC San Diego just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode."

20 Apr 2009

A bright future for biological sensors

In the future, explained Peter Ghazal, Chair of Edinburgh University's Department of Molecular Genetics and Biomedicine, biological sensors, the product of the integration of biology and electronics will be used to detect infections and prescribe personalized treatments.

15 Apr 2009

Helicos BioSciences releases transcriptome sequencing datasets as open access

Helicos BioSciences has announced the release of transcriptome sequencing (RNA-Seq) datasets on the HeliSphere Technology Center, the company's open access Web site for sharing Helicos datasets and bioinformatics software tools.

6 Apr 2009

2,516 potential biomarkers of pancreatic cancer

A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreatic cancer.

6 Apr 2009

Evolutionary origin of bacterial chromosomes revealed

Researchers have unveiled the evolutionary origin of the different chromosomal architectures found in three species of Agrobacterium.

29 Mar 2009

Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment

Metabolites are molecular fingerprints of what your cells are up to and Dr. Arun Sreekumar wants to know the impression made by cancer.

23 Mar 2009

DNA duplication - mechanism for 'survival of the fittest'

Some 65 million years ago, the earth's most recent 'mass extinction' took place.

23 Mar 2009

Coenzyme rare to bacteria critical to Mycobacterium tuberculosis survival

Coenzyme F420, a small molecule that helps certain enzymes transfer electrons, is found in microorganisms known as methane-producing archaea, some of which thrive in extreme environments.

23 Mar 2009

New nanotechnology treatment for drug addiction

A precise, new nanotechnology treatment for drug addiction may be on the horizon as the result of research conducted at the University at Buffalo.

23 Mar 2009

New RNA-Seq technique used to profile anthrax genome

Scientists at the Georgia Institute of Technology have used a new approach, known as RNA-Seq, to profile the gene expression of the bacterium that causes anthrax, Bacillus anthracis.

22 Mar 2009

Researchers show how proteins find the right DNA sequences

Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes.

16 Mar 2009

Proteomics study shows that genes involved in invertebrate longevity have surprising parallels in humans

Prolexys Pharmaceuticals has announced the publication of the discovery of genes that are likely to have a role in the aging process of humans.

15 Mar 2009

Bioinformatics sheds light on evolutionary origin of Rickettsia virulence genes

Scientists from the Virginia Bioinformatics Institute (VBI) at Virginia Tech, the University of Maryland School of Medicine, and the University of Louisville have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution.

11 Mar 2009

University at Buffalo to receive $4.9 million in stem cell research funds from New York State

The University at Buffalo will receive $4.9 million in funding to conduct research on stem cells, part of a new investment in stem cell research announced yesterday by New York State Governor David A. Paterson.

11 Mar 2009

Protein structures reveal "big bang" of innovation in evolution

A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms.

11 Mar 2009

Patented inventions double at University at Buffalo

An antibody with the potential to stop breast cancer in its path. A nanoparticle that can address a side effect of the treatment that hemophiliacs cannot live without. A "quantum dot" with the potential to treat cancer or harvest the power of the sun. An air purifier that kills the world's nastiest toxins.

5 Mar 2009

UB and AHRM, Inc. help Buffalo join the electronic medical revolution

The Obama administration's push to move health care from handwritten charts and prescriptions into the electronic age is getting a boost in Western New York with new funding to establish a Medication Management Research Network in the University at Buffalo's New York State Center of Excellence in Bioinformatics and Life Sciences.

3 Mar 2009

New software aids discovery of new genetic markers for diseases

Modern genotyping technologies offer new opportunities to explore how genes influence health and disease, but also present the challenge of analyzing huge amounts of genetic and clinical data.

26 Feb 2009