Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Potentially useful biomarker tests for molecularly targeted therapies are not being adopted appropriately into clinical practice because of a lack of common evidentiary standards necessary for regulatory, reimbursement, and treatment decisions.

7 Mar 2016

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with low survival rates, with newly diagnosed patients surviving a median of 14 months and recurrent patients surviving a median of only 3 to 9 months. New therapeutic targets and biomarkers for prognosis are urgently needed.

7 Mar 2016

Study on DNA scrunching may aid in developing new antimicrobial medicines

A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins to direct the synthesis of RNA. This finding may aid in the discovery of new antimicrobial medicines, and the powerful technological approaches developed for this research may shed light on other essential cellular processes.

4 Mar 2016

Lewin-Cameron Laboratory at Doherty Institute selects OpenSpecimen system to manage biospecimens inventory

In the short time that AXT have been promoting OpenSpecimen, the bioinformatics platform for managing biospecimens inventory developed by Krishagni Solutions in conjunction with the National Cancer Institute, it has generated large amounts of interest in Australia.

From AXT Pty Ltd 2 Mar 2016

New screening technique to test drug compounds used in Ewing sarcoma treatment

In Ewing sarcoma, cancer cells' DNA is unwound abnormally from a condensed, compact state. Once sections of genetic code are open, key genes are turned on to help direct aggressive and cancerous cell growth.

1 Mar 2016

Novel way proposed for developing infectious disease models to uncover hidden patterns of transmission

Ebola. Chikungunya. Zika. Once rare and exotic pathogens keep popping up and turning into household names. It's the new reality as the climate warms, humans expand more into wildlife habitats and air travel shrinks the distances across the globe.

27 Feb 2016

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.

27 Feb 2016

Luminex collaborates with University of São Paulo to validate multi-analyte Zika virus assay

Luminex Corporation today announced it is collaborating with the Laboratory of Molecular Evolution & Bioinformatics, Biomedical Sciences Institute, University of São Paulo, Brazil to validate a multi-analyte Zika virus assay developed by Luminex partner, GenArraytion, Inc.

26 Feb 2016

Gene expression analysis points metastatic CRC patient to successful irbesartan therapy

A patient with recurrent metastatic colorectal cancer has been successfully treated with the angiotensin receptor blocker irbesartan, researchers report.

24 Feb 2016

Diversigen, Baylor Miraca to provide customers access to targeted genomics and metabolomics services

Diversigen, Inc., the leading provider of comprehensive microbiome analysis services, today announced a strategic partnership with Baylor Miraca Genetics Laboratories, a global leader in genetic testing, to provide their customers access to a broad range of targeted genomics and metabolomics services.

23 Feb 2016

SIFT 4G software can lead to faster genome analysis

An international team of scientists, led by researchers from A*STAR's Genome Institute of Singapore (GIS) and the Bioinformatics Institute (BII), have developed SIFT 4G (SIFT for Genomes) - a software that can lead to faster genome analysis.

23 Feb 2016

Researchers investigate effect of naturally-derived pigment ASX on hippocampal function

With the recent rise in popularity of naturally-derived supplements to maintain a healthy body, there has been a great deal of attention toward development of the so-called "brain foods", which can enhance brain function. Of particular importance is the natural red pigment astaxanthin (ASX) abundant in both salmon and in crustaceans such as shrimp and crab.

22 Feb 2016

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Novel approaches for manipulating the gut microbiota through diet, pre- and probiotics, targeted antibiotic therapy and fecal microbiota transplantation for health maintenance and treatment are under investigation or already in use.

22 Feb 2016

Silicon Biosystems Menarini, Macrogen to jointly develop genomic cancer tests

Silicon Biosystems Menarini and Macrogen, Inc. today announced they will form a partnership to provide clinical assays and innovative procedures for precision medicine in cancer.

12 Feb 2016

Distinctive gene 'signature' may lead to new way to diagnose Lyme disease

Researchers at UC San Francisco and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene "signature" they discovered in white blood cells of patients infected with the tick-borne bacteria.

12 Feb 2016

Tick genome study sheds light on occurrences of Lyme disease

After a decade-long research effort the genome of the deer tick has been sequenced by an international team of scientists, including researchers from the SIB Swiss Institute of Bioinformatics.

12 Feb 2016

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is frequently mutated in children on the autism spectrum. In older men and women, ADNP expression in the blood is correlated with cognition and further altered in Alzheimer's disease.

11 Feb 2016

New initiative aims to improve access to PTSD research

Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Cohen Veterans Bioscience and Exaptive Inc. today announced a new initiative to improve access to post-traumatic stress disorder (PTSD) research. The creation of a PTSD KnowledgeMap  will systematize the current PTSD research space and provide interactive tools for scientists and others studying PTSD.

11 Feb 2016

Researchers find new mutation signature in cancer cells

Mutations are the replacement of DNA bases known as Adenine (A), Cytosine (C), Guanine (G) and Thymine (T) with other bases. When mutations such as C to T or G to A are found within a specific DNA sequence, this is known as a mutation signature.

10 Feb 2016

UM SOM researchers reveal genetic makeup of various strains of E. coli

A multi-disciplinary group of researchers at the University of Maryland School of Medicine have for the first time determined the genetic makeup of various strains of E. coli, which every year kills hundreds of thousands of people around the world.

9 Feb 2016

Bioinformatics News and Research

Further Reading

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Expression of BIRC3 protein associated with poor survival, recurrent disease in GBM patients

Study on DNA scrunching may aid in developing new antimicrobial medicines

Lewin-Cameron Laboratory at Doherty Institute selects OpenSpecimen system to manage biospecimens inventory

New screening technique to test drug compounds used in Ewing sarcoma treatment

Novel way proposed for developing infectious disease models to uncover hidden patterns of transmission

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

Luminex collaborates with University of São Paulo to validate multi-analyte Zika virus assay

Gene expression analysis points metastatic CRC patient to successful irbesartan therapy

Diversigen, Baylor Miraca to provide customers access to targeted genomics and metabolomics services

SIFT 4G software can lead to faster genome analysis

Researchers investigate effect of naturally-derived pigment ASX on hippocampal function

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Silicon Biosystems Menarini, Macrogen to jointly develop genomic cancer tests

Distinctive gene 'signature' may lead to new way to diagnose Lyme disease

Tick genome study sheds light on occurrences of Lyme disease

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

New initiative aims to improve access to PTSD research

Researchers find new mutation signature in cancer cells

UM SOM researchers reveal genetic makeup of various strains of E. coli

Lab Diagnostics and Automation - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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