Bioluminescence News and Research

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Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

An intriguing new study presents a novel approach to biosensor-based evaluation of promising drugs that could inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via its 3C-like protease (3CLpro), a viral protease.

2 Aug 2021

New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian cancer

Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced successful results, dramatically limiting tumor growth and decreasing tumor mass.

11 Jun 2021

Light-controlled on/off switch helps control biological clock in cultured cells, explanted tissue

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally.

27 May 2021

New noninvasive imaging device could be used in biomedical research, translational medicine

A biochemical reaction between an enzyme called luciferase and oxygen causes fireflies to glow and is considered one of the most well-known examples of bioluminescence in nature.

12 May 2021

New system facilitates real-time imaging of biological, pathological processes

Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have developed a novel far-red light-emitting luciferin-luciferase system that is more efficient than those available commercially. An article on the subject is published in the International Journal of Molecular Sciences.

30 Mar 2021

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

24 Mar 2021

Scientists successfully restore circadian function in the liver of arrhythmic mice

Circadian clocks, which regulate the metabolic functions of all living beings over a period of about 24 hours, are one of the most fundamental biological mechanisms.

18 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

American scientists receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize

FRANKFURT am MAIN. Two American scientists, Bonnie L. Bassler and Michael R. Silverman, receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize, which is endowed with 120,000 €.

28 Jan 2021

Reliable Antibodies Testing for SARS-CoV-2

In this interview, Poncho Meisenheimer, VP of R&D at Promega, talks to News-Medical Life Sciences about the importance of having the reliability for SARS-Co-V-2 antibody tests.

From Promega Corporation 15 Dec 2020

High seroprevalence of short-lived anti-SARS-CoV-2 antibodies in Paris

A recent study indicates a high seroprevalence of antibodies against SARS-CoV-2 among individuals working in a Paris-based institute.

3 Dec 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Seroprevalence and immune response to SARS-CoV-2 in Paris

François Anna et al. published this study in a recent medRxiv* preprint paper, where they present the results of assessing the serological response in the selected population. They tested for specific IgG response against the SARS CoV-2 Nucleoprotein and Spike protein and performed a pseudo-neutralization assay in sera of urban dwellers in Paris.

30 Oct 2020

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

AXT is excited to add the Vieworks range of bio-imaging systems to their preclinical imaging product portfolio. Their in-vivo imaging systems provide outstanding performance in bioluminescent and fluorescent imaging and represents excellent value.

From AXT Pty Ltd 26 Sep 2020

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

A research group from Slovenia, Switzerland, and Germany shows how nanoscaffolded assemblies may neutralize interaction between the SARS-CoV-2 spike protein and cell receptor, providing adequate protection in a surrogate infection assay and warranting the advance of such platforms in the pursuit for the effective vaccine.

31 Aug 2020

Bioluminescence News and Research

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian cancer

Light-controlled on/off switch helps control biological clock in cultured cells, explanted tissue

New noninvasive imaging device could be used in biomedical research, translational medicine

New system facilitates real-time imaging of biological, pathological processes

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

Scientists successfully restore circadian function in the liver of arrhythmic mice

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

American scientists receive the 2021 Paul Ehrlich and Ludwig Darmstaedter Prize

Reliable Antibodies Testing for SARS-CoV-2

High seroprevalence of short-lived anti-SARS-CoV-2 antibodies in Paris

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Seroprevalence and immune response to SARS-CoV-2 in Paris

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

New bioluminescent reporter developed to track DNA double stranded break repair

Promega introduces new serological antibody test for COVID-19

Bioluminescent molecule in fireflies shines light on mitochondrial activity

Method provides new insight into brain cells that maintain body's master circadian clock.

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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