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Innovations in baculovirus–insect cell expression systems

The baculovirus–insect cell expression system—insect cells used in conjunction with the baculovirus expression vector system (BEVS)— remains a crucial technology for manufacturing large and complex proteins. This eukaryotic expression system offers inherent safety, ease of scale-up, flexible product design, and versatility for a broad range of proteins.

From Sino Biological Inc. 20 Sep 2023

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Clinical trials have begun for a drug candidate for hard-to-treat cancers, discovered at the University of Edinburgh and licensed by US biopharmaceutical company Nuvectis Pharma, Inc.

15 Sep 2023

Organon Bolsters Research & Development Expertise with Two Leadership Appointments

Organon (NYSE: OGN), a global healthcare company with a focus on women’s health, today announced the appointment of Juan Camilo Arjona Ferreira, M.D., as Chief Medical Officer (CMO) and Charlotte Owens, M.D., as Head of Medical Affairs and Outcomes Research.

7 Sep 2023

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the acquisition of BioPharmics LLC.

From Optibrium Ltd. 31 Aug 2023

Drexel University receives grants to support cell and gene therapy education

Drexel University's School of Biomedical Engineering, Science and Health Systems, in collaboration with Drexel's College of Medicine, has received grants from the pharmaceutical company Bristol Myers Squibb, to support the education and training of diverse and talented students looking to pursue careers in cell and gene therapy.

25 Aug 2023

Speech Accessibility Project needs more participants with Parkinson's

The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson's.

24 Aug 2023

New treatment approach shows promise in reversing hormone resistance in breast cancer

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

9 Aug 2023

Researchers develop antibody drugs from tobacco plants for cancer treatment

For the first time in Thailand, lecturers at Chulalongkorn University's Faculty of Pharmaceutical Sciences have successfully developed antibody from tobacco plants with inhibitory effects on the growth of cancer cells in laboratory animals.

9 Aug 2023

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

In a study published in the journal Foods, researchers reviewed available literature on the potential anti-Alzheimer's disease properties of mushrooms.

9 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications.

1 Aug 2023

Gyros Protein Technologies introduces PurePep EasyClean Auto Kit for automated parallel peptide purification

Gyros Protein Technologies AB, a leading provider of peptide synthesizers and reagents, and a pioneer in automated nanoliter-scale immunoassays, today announced the launch of its PurePep® EasyClean (PEC) Auto Kit for the automated parallel purification of peptides, accelerating downstream processes for research, development, and production of simple to complex peptide drugs and therapies.

From Gyros Protein Technologies AB 31 Jul 2023

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Osivax, a biopharmaceutical company developing vaccines to provide broad-spectrum protection against highly mutating infectious viruses, today announced that The Lancet Infectious Diseases published results from the company's OVX836-003 study under the title, "Immunogenicity, safety and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: randomized, double-blind placebo-controlled, Phase 2a trial."

27 Jul 2023

Advancing new antibiotics through the later stages of clinical testing

A report by University of Queensland researchers has warned a global crisis of antibiotic resistance is inevitable, despite promising developments in new antibiotics.

25 Jul 2023

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT).

21 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

PhoreMost appoints Professor Peter Parker and Dr Jason Imbriglio to Scientific Advisory Board

PhoreMost Ltd. announced Professor Peter Parker and Dr Jason Imbriglio as members of its Scientific Advisory Board (SAB).

From PhoreMost 17 Jul 2023

Innovative mixed reality training platform to be developed for pharmaceutical companies and healthcare

UK immersive technology company FourPlus, along with collaborators Holosphere and the Cell and Gene Therapy Catapult, have been awarded funding from Innovate UK to create and test a mixed reality training platform that enables customised training delivery for pharmaceutical companies and healthcare.

17 Jul 2023

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced updates to its flagship platform, Cyto-Mine®, enabling it to be compliant with current Good Manufacturing Practice (cGMP) regulations enforced by the US FDA.

From Sphere Fluidics 6 Jul 2023

Biopharmaceutical News and Research

Innovations in baculovirus–insect cell expression systems

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Organon Bolsters Research & Development Expertise with Two Leadership Appointments

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Drexel University receives grants to support cell and gene therapy education

Speech Accessibility Project needs more participants with Parkinson's

New treatment approach shows promise in reversing hormone resistance in breast cancer

Researchers develop antibody drugs from tobacco plants for cancer treatment

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Gyros Protein Technologies introduces PurePep EasyClean Auto Kit for automated parallel peptide purification

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Advancing new antibiotics through the later stages of clinical testing

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

PhoreMost appoints Professor Peter Parker and Dr Jason Imbriglio to Scientific Advisory Board

Innovative mixed reality training platform to be developed for pharmaceutical companies and healthcare

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

Biotechnology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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