Blindness News and Research

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Brazilian study uncovers reorganization of anatomical structures in the brains of congenitally blind people

Recently published in the scientific journal Human Brain Mapping, a Brazilian study has identified for the first time the reorganization of anatomical structures in the brain of people with congenital blindness.

20 Jan 2023

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

The leading cause of blindness in American adults is diabetic retinopathy, progressive damage to blood vessels in the light-sensitive tissue at the back of the eye.

14 Jan 2023

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Researchers successfully demonstrated that lab-grown retinal organoids made new synaptic connections, theoretically establishing their potential to treat blindness due to retinal degenerative diseases.

13 Jan 2023

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Oregon State University College of Pharmacy scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition.

11 Jan 2023

Study: Two separate eye diseases may contribute to age-related macular degeneration

Two separate eye diseases may contribute to age-related macular degeneration (AMD), a leading cause of blindness in the United States, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

9 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Mouse study identifies potential targets for treating dry eye disease and corneal injury

People with a condition known as dry eye disease are more likely than those with healthy eyes to suffer injuries to their corneas.

2 Jan 2023

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

The Children’s Tumor Foundation (CTF) has announced a groundbreaking 3-year study, which it will fund for nearly $2 million, to determine if a DNA-based blood test can offer better understanding and ultimately earlier diagnosis of cancer predisposition in neurofibromatosis type 1 (NF1) patients.

16 Dec 2022

Major funding to support studies of the PRPH2 gene linked to macular dystrophy

In healthy vision, a gene called PRPH2 provides instructions to make a protein called peripherin 2 (PRPH2), which plays a key role in the normal functioning of photoreceptors that detect light and color and which line the back of the eye.

16 Dec 2022

The disability tax: Medical bills remain inaccessible for many blind Americans

A Missouri man who is deaf and blind said a medical bill he didn't know existed was sent to debt collections, triggering an 11% rise in his home insurance premiums.

2 Dec 2022

Study shows only 75.8% of children under 15 have antibodies against measles

A study conducted in Brazil and reported in an article in Vaccines shows that in the São José do Rio Preto region in the northwest of São Paulo state, only 75.8% of children aged 0-15 have antibodies against measles.

1 Dec 2022

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

Scientists discover new potential mechanism for vision loss

Visual cells in the human retina may not simply die in some diseases, but are mechanically transported out of the retina beforehand.

1 Dec 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022

Repetitive stress induces features of accelerated aging in the eye

New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.

21 Nov 2022

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual scientific meeting, found that the recommended weight-based or non-weight-based dose of hydroxychloroquine led to more hospitalizations for flares among patients with systemic lupus erythematosus

8 Nov 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

New analysis highlights the need to prioritize addressing preventable vision loss in children in America

An analysis of the nation's first and largest comprehensive eye disease registry, the IRIS® Registry, sheds new light on what we thought we knew about childhood blindness in the United States: The leading causes appear to be retinopathy of prematurity (ROP), nystagmus, and cataract, mostly treatable and preventable causes.

3 Oct 2022

Blindness News and Research

Brazilian study uncovers reorganization of anatomical structures in the brains of congenitally blind people

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Study: Two separate eye diseases may contribute to age-related macular degeneration

History of obesity produces changes in innate immunity and neuroinflammation

Mouse study identifies potential targets for treating dry eye disease and corneal injury

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

Major funding to support studies of the PRPH2 gene linked to macular dystrophy

The disability tax: Medical bills remain inaccessible for many blind Americans

Study shows only 75.8% of children under 15 have antibodies against measles

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

Scientists discover new potential mechanism for vision loss

Endogenous system may be responsible for delayed onset of diabetic retinopathy

Previously unknown links between genetic factors in ASD identified

Repetitive stress induces features of accelerated aging in the eye

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

NEI researchers create a high-resolution map of retinal cell chromatin contract points

New analysis highlights the need to prioritize addressing preventable vision loss in children in America

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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