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Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause

Secondary analyses of findings from the Women's Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause.

3 Apr 2007

Australian Tissue Bank may help find breakthrough in the fight against cancer

The cure for cancer is one step closer this week with the first collections of cancer tissue taking place at the new Wesley Research Institute Tissue Bank.

3 Apr 2007

Researchers discover factor that controls blood sugar's manufacture in a novel way

Researchers have discovered a factor that controls blood sugar's manufacture in a novel way: by limiting the supply of its building blocks. The findings are reported in the April issue of the journal Cell Metabolism, published by Cell Press.

3 Apr 2007

Obstetric fistula, impact on women

Reuters on Friday examined obstetric fistula and its impact on women living with the condition (Ringler, Reuters, 3/30). Obstetric fistulas develop when a fetus becomes lodged during labor in the narrow birth canal of a girl or young woman, causing pressure that blocks the flow of blood to vital tissues and tearing holes in the bowel, urethra or both, causing incontinence.

3 Apr 2007

Filtering white cells from donor blood before transfusion is much safer for patients

The practice of removing the white cells from blood is called leukoreduction. But despite the recommendations of two national advisory committees in 10 years that voted in favor of all patients in the United States receiving leukoreduced blood, ("universal leukoreduction"), the practice is still not wholly supported in the medical community, nor recommended by the Food and Drug Administration. Part of the reason is fear of increased cost.

3 Apr 2007

Researchers spot molecular player in insulin resistance and type 2 diabetes

Scientists at Weill Cornell Medical College have identified a protein called Rab10 as an important partner in the insulin-mediated uptake of glucose by cells, opening the way to potential new drug targets for the prevention and treatment of type 2 diabetes.

3 Apr 2007

Embolic protection and platelet inhibition during renal artery stenting

High blood pressure is the most common chronic medical condition in the United States, and the most common identifiable cause is narrowing of a kidney artery, called renal artery stenosis.

3 Apr 2007

Long-term safety of drug-eluting stents in off-label use

Research presented at the American College of Cardiology's Innovation in Intervention: i2 Summit 2007 in New Orleans, La, paints a picture of the "real world" use of drug-eluting stents and offers new insight into the connection between blood clotting, or thrombosis, in the stent - a dangerous complication - and adherence and responsiveness to anti-clotting medication.

3 Apr 2007

Advances in clinical cardiology

Three studies being presented at the American College of Cardiology's Innovation in Intervention: i2 Summit 2007 in New Orleans, La., highlight the breadth of research propelling advances in clinical cardiology.

3 Apr 2007

Shoulder arthroplasty to relieve pain has no greater risk of complications than replacement of other major joints

Contrary to widespread belief, total surgical replacement of arthritic shoulder joints carries no greater risk of complications than replacement of other major joints, a Johns Hopkins study suggests.

3 Apr 2007

Severe dengue infections may go unrecognized in international travelers

Severe cases of a common travelers' infection may not be recognized if doctors rely on the World Health Organization's (WHO) guidelines for identifying it, according to a new study published in the April 15 issue of The Journal of Infectious Diseases, now available online.

3 Apr 2007

Trial of percutaneous coronary intervention added to optimal medical therapy in patients with stable coronary heart disease

Percutaneous coronary interventions (PCI) involve opening partially blocked arteries to improve blood flow to the heart. These procedures are performed more than 1 million times a year.

3 Apr 2007

We need to balance out our intake of omega-6 and omega-3 fatty acids

A new study suggests that people whose diets contain dramatically more of one kind of polyunsaturated fatty acid than another may be at greater risk for both clinical depression and certain inflammatory diseases.

3 Apr 2007

New blood thinner thrombin-receptor antagonist may work without bleeding risk

When studying a new blood thinner, one of the first signs the drug is working is seeing a slight increase in minor bleeding, nose bleeds and bruising, an inconvenient side effect of preventing the blood clots that are the leading cause of heart attack and stroke.

3 Apr 2007

Regular health exams increase likelihood that older adults will get recommended cancer screenings

If you're 50 or older, seeing your doctor every year or two for a checkup may be a good defense against cancer, according to a new study by researchers at UC Davis, the University of Washington, and Group Health Cooperative in Seattle.

2 Apr 2007

Dual renin system blocking drug combo provides additional blood pressure-lowering effects

A combination of two medicines that act against the effects of the enzyme renin are more effective in lowering blood pressure than either of the medicines alone, according to a study presented today at the American College of Cardiology's 56th Annual Scientific Session.

2 Apr 2007

$Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock$

Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock

Patients with acute coronary syndromes (ACS), such as heart attack and recent-onset chest pain, remain at considerable risk of experiencing further serious cardiovascular problems despite improvements in care.

2 Apr 2007

Tilarginine does not reduce risk of death after heart attack

The medication tilarginine, a drug that was believed could be beneficial for patients who develop cardiogenic shock (low blood pressure due to impaired cardiac function) after a heart attack, did not reduce the risk of death up to six months after a heart attack, according to a JAMA study published online March 26.

2 Apr 2007

Effect of Torcetrapib on the progression of coronary atherosclerosis

Investigators report that torcetrapib, a drug that substantially raises high-density lipoprotein cholesterol or HDL (the "good" cholesterol), did not slow the progression of plaque buildup in the coronary arteries as measured using an ultrasound probe (IVUS).

2 Apr 2007

Addition of torcetrapib to statin therapy has no benefit for atherosclerosis progression

For some patients with high cholesterol, even the most aggressive treatment with statin drugs fails to prevent coronary artery disease.

2 Apr 2007

Blood News and Research

Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause

Australian Tissue Bank may help find breakthrough in the fight against cancer

Researchers discover factor that controls blood sugar's manufacture in a novel way

Obstetric fistula, impact on women

Filtering white cells from donor blood before transfusion is much safer for patients

Researchers spot molecular player in insulin resistance and type 2 diabetes

Embolic protection and platelet inhibition during renal artery stenting

Long-term safety of drug-eluting stents in off-label use

Advances in clinical cardiology

Shoulder arthroplasty to relieve pain has no greater risk of complications than replacement of other major joints

Severe dengue infections may go unrecognized in international travelers

Trial of percutaneous coronary intervention added to optimal medical therapy in patients with stable coronary heart disease

We need to balance out our intake of omega-6 and omega-3 fatty acids

New blood thinner thrombin-receptor antagonist may work without bleeding risk

Regular health exams increase likelihood that older adults will get recommended cancer screenings

Dual renin system blocking drug combo provides additional blood pressure-lowering effects

Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock

Tilarginine does not reduce risk of death after heart attack

Effect of Torcetrapib on the progression of coronary atherosclerosis

Addition of torcetrapib to statin therapy has no benefit for atherosclerosis progression

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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