Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

Recommendation that physicians be a little more cautious in deciding against tPA treatment

Although use of the clot-dissolving drug tissue plasminogen activator (tPA) has revolutionized the treatment of acute stroke patients, many of those who could receive the drug do not because their initial symptoms appear mild or improve soon after they arrive at the hospital.

9 Oct 2005

New role for the blood protein serum amyloid P in the body's response to medical materials

Using a technique called proteomics, the researchers identified many of the blood proteins that stick (adsorb) to the surfaces of medical devices. Blood proteins that adsorb to the surfaces of materials unfold and can be recognized by the body, which then mounts a response against the device.

5 Oct 2005

Ischemic brain injury - another promising avenue for stem cell therapy

Adult stem cell therapy quickly and significantly improves recovery of motor function in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy, researchers report.

4 Oct 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Still a long way to go in diagnostic evaluation of all patients who suffer ischemic strokes

Women who survive a stroke are less likely than men to get crucial tests of their heart and neck arteries that can help improve their treatment and reduce their risk of a second stroke, a new University of Michigan study finds.

27 Sep 2005

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

A fender-bender may have saved Douglas Collins' life. A CT scan following the accident discovered Collins, 64, had a brain aneurysm, a weakness in the arterial wall that if ruptured could cause a stroke or death. It was not caused by the accident, but likely could have been a ticking time bomb present for years. The aneurysm was large and previously thought to require open surgery and a lengthy recovery.

26 Sep 2005

Link between ambient air pollution and acute myocardial infarction, or heart attack

An article published in the Journal of Thrombosis and Haemostasis looks specifically at airborne particulate matter resulting mainly from the combustion of fuel, including coal and also from forest fires.

26 Sep 2005

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

A large-scale study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that heavy alcohol consumption - 35 or more drinks per week -- can significantly increase men's risk of developing atrial fibrillation, a dangerous type of arrhythmia and one of the leading risk factors for stroke.

20 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Large scale study to see if angioplasty can be safely performed in small hospitals

Cardiologists at Johns Hopkins have launched a nationwide study of more than 16,000 patients to see if a potentially life-saving procedure called angioplasty can be safely performed in smaller, community hospitals, easing access to the therapy for patients. Researchers expect to enroll the first study patients in early fall 2005.

12 Sep 2005

More heart victims die when clot-buster drug is used before angioplasty

Currently it is fairly common practice to give heart attack patients a clot-busting drug a few hours before planned angioplasty.

7 Sep 2005

Testing for specific breast cancer genes unadvisable if no family history of disease exists

According to the Preventive Services Task Force in the U.S., routine testing for mutations in the BRCA1 and BRCA2 genes, which have been linked to breast and ovarian cancer, are not advised unless women have a family history of the disease.

7 Sep 2005

Catheter interventions help to prevent stroke

According to WHO statistics, stroke is the second most frequent cause of death worldwide. Cardiac causes account for up to 20% of strokes. Transcatheter occlusion of patent foramen ovale and left atrial appendage eliminate the most important sources for cardiac embolism.

6 Sep 2005

Vitamin B may do more harm than good in heart attack patients

Researchers from Norway have found that treating patients who have had a heart attack with high doses of B vitamins does not lower the risk of getting another heart attack or stroke. Contrary to expectations, B vitamins may do more harm than good.

5 Sep 2005

Use of the antiplatelet drug clopidogrel before a coronary angioplasty reduces risk of cardiovascular death

Use of the antiplatelet drug clopidogrel before a coronary angioplasty reduced the risk of cardiovascular death, heart attack or stroke within 30 days following the procedure, according to an article in the September 14 issue of JAMA: The Journal of the American Medical Association.

5 Sep 2005

World's largest study on acute coronary syndromes

A Canadian-led study involving researchers from 41 countries has demonstrated in the world's largest study of acute coronary syndromes (ACS) that a new anti-thrombotic therapy is safer and as effective as the traditional therapy used in preventing heart attacks, death and ischemia in people with serious heart conditions.

5 Sep 2005

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (Revlimid) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. Results of a Phase II clinical trial were published online Aug. 23 in Blood.

1 Sep 2005

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Collagen often pops up in beauty products and supermodel lips. But by mating collagen with a molecular hitchhiker, materials scientists at Johns Hopkins hope to create some important medical advances.

30 Aug 2005

Aspirin shown to be beneficial before heart surgery

Surgeons who have been advising their patients to avoid taking aspirin in the days before surgery because they feared it could cause bleeding, will be reassured by the results of a new study.

30 Aug 2005

Blood Clot News and Research

Further Reading

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

Recommendation that physicians be a little more cautious in deciding against tPA treatment

New role for the blood protein serum amyloid P in the body's response to medical materials

Ischemic brain injury - another promising avenue for stem cell therapy

The immune mechanisms of atherosclerosis

Still a long way to go in diagnostic evaluation of all patients who suffer ischemic strokes

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

Link between ambient air pollution and acute myocardial infarction, or heart attack

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Large scale study to see if angioplasty can be safely performed in small hospitals

More heart victims die when clot-buster drug is used before angioplasty

Testing for specific breast cancer genes unadvisable if no family history of disease exists

Catheter interventions help to prevent stroke

Vitamin B may do more harm than good in heart attack patients

Use of the antiplatelet drug clopidogrel before a coronary angioplasty reduces risk of cardiovascular death

World's largest study on acute coronary syndromes

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Aspirin shown to be beneficial before heart surgery

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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