Blood Sugar News and Research

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Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population-based cohort study

Rosiglitazone, a drug used to treat type 2 diabetes, is associated with an increased risk of heart failure and death among older patients compared to a similar drug (pioglitazone), concludes a study published on bmj.com today.

20 Aug 2009

Survey aims to better understand daily needs of unpaid caregivers of people with diabetes

Chevy Chase, MD-The Hormone Foundation, the public education affiliate of The Endocrine Society, in collaboration with the National Alliance for Caregiving, today released key findings from a first-of-its-kind survey (http://www.hormone.org/Public/diabetes_caregiver.cfm) aimed at better understanding the daily needs and struggles of unpaid caregivers of people with diabetes.

19 Aug 2009

Efforts to create treatment guidelines are often complicated

The development of treatment guidelines for illnesses such as diabetes is a complicated process.

19 Aug 2009

Tissue scarring key to link between obesity and diabetes

The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring.

13 Aug 2009

Researchers respond to concerns about international insulin drug trial

Accumulating safety data from the large, international ORIGIN trial have been reviewed by its independent data monitoring committee, who have concluded that there is no cause for concern.

12 Aug 2009

Insulin and type 2 diabetes - fears are largely unfounded

People diagnosed with type 2 diabetes often resist taking insulin because they fear gaining weight, developing low blood sugar and seeing their quality of life decline.

11 Aug 2009

Discovery of gene that may play a role in the development of type 1 diabetes

Scientists at Stanford University have identified a gene that may play a role in the development of type 1 diabetes, an autoimmune disease in which the immune system attacks the body's insulin-producing cells. Insulin, a hormone produced by cells of the pancreas, helps the body to absorb sugars found in food and to maintain blood sugar at appropriate levels.

10 Aug 2009

More insulin-producing cells from a single transcription factor switch

Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal.

7 Aug 2009

New approach targets gut hormone to lower blood sugar levels

A research team led by Dr. Tony Lam at the Toronto General Research Institute and the University of Toronto discovered a novel function of a hormone found in the gut that might potentially lower glucose levels in diabetes.

6 Aug 2009

In Massachusetts, a radical idea for changing how doctors are paid

Dr. Richard Lopez is chief physician at Atrius Health in Boston. He says "global payments" allow health care providers to innovate to keep patients out of the hospital. (Richard Knox/NPR)

6 Aug 2009

Discovery of novel function of hormone found in gut that may lower glucose levels in diabetes

5 Aug 2009

High levels of glutamate in brain linked to depression, low cognitive function

Researchers at the Joslin Diabetes Center and several other institutions have for the first time linked high levels of glutamate – a neurotransmitter in the brain produced from glucose – in people with type 1 diabetes to symptoms of depression and lower levels of cognitive performance. The findings may lead to a better understanding of the underlying mechanisms of these conditions in people with diabetes.

4 Aug 2009

Elevated cholesterol levels in midlife raises risk of late-life dementia

Elevated cholesterol levels in midlife - even levels considered only borderline elevated - significantly increase the risk of Alzheimer's disease and vascular dementia later in life, according to a new study by researchers at Kaiser Permanente's Division of Research and the University of Kuopio in Finland. The study appears in the journal Dementia & Geriatric Cognitive Disorders.

4 Aug 2009

FDA approves Onglyza (saxagliptin) for type 2 diabetes

The U.S. Food and Drug Administration has approved Onglyza (saxagliptin), a once-daily tablet to treat Type 2 diabetes in adults. The medication is intended to be used with diet and exercise to control high blood sugar levels.

2 Aug 2009

Short-term complications after bariatric surgery for extreme obesity low

Short-term complications and death rates were low following bariatric surgery to limit the amount of food that can enter the stomach, decrease absorption of food or both, according to the Longitudinal Assessment of Bariatric Surgery (LABS-1). The study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. Results are reported in the July 30 issue of the New England Journal of Medicine.

30 Jul 2009

Dental problems may predict future medical issues

Dental disease may be a wake-up call that your diet is harming your body. "The five-alarm fire bell of a tooth ache is difficult to ignore," says Dr. Philippe P. Hujoel, professor of dental public health sciences at the University of Washington (UW) School of Dentistry in Seattle. Beyond the immediate distress, dental pain may portend future medical problems. It may be a warning that the high-glycemic diet that led to dental problems in the short term may, in the long term, lead to potentially serious chronic diseases.

9 Jul 2009

Health reform legislation will impact preventive and wellness programs

Reuters reports: "Efforts to overhaul the U.S. healthcare system and expand coverage to millions of uninsured could lead some wellness programs to expand and others to constrict, experts say.... In all of the bills in Congress, insurers would be required to cover some preventive services, and all of the bills include prevention and wellness incentives.

8 Jul 2009