Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

UK’s first robotic genomic testing facility for cancer patients launches

For the first time in the UK, robotic technology is being used to support genomic testing for cancer patients following a partnership between The Royal Marsden NHS Foundation Trust and Automata Technologies, a leading automation company powering automation in life sciences labs.

From Automata 6 Sep 2024

Cancer drug offers life-changing results for severe lupus patient

The team at Charité – Universitätsmedizin Berlin is astounded by the huge improvement seen in a female patient with severe systemic lupus erythematosus (SLE) after being treated with the cancer medication teclistamab. Not long ago, the 23-year-old was wheelchair-bound due to the autoimmune disease.

6 Sep 2024

Early cholesterol spikes fuel atherosclerosis by altering macrophages

Early intermittent hyperlipidemia significantly accelerates atherosclerosis by disrupting macrophage function, highlighting the need for early cholesterol management.

6 Sep 2024

Aging immune system fuels cancer growth

A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults.

6 Sep 2024

Study links monoclonal B-cell lymphocytosis to elevated melanoma risk

About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems.

5 Sep 2024

Investigating inflammatory memory in hematopoietic stem cells within the AML niche

A new research perspective was published in Oncotarget's Volume 15 on September 4, 2024, entitled, "Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche."

5 Sep 2024

Study links periodontal bacteria to worsening rheumatoid arthritis

Periodontal disease, which affects the gums and tissues that surround the teeth, is one of the most prevalent dental conditions worldwide.

5 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

Research unveils how HMGA2 regulates stress responses in stem cells

Kumamoto University researchers have made a groundbreaking discovery that sheds light on how the HMGA2 gene-;an essential transcriptional activator involved in chromatin modification-;regulates stress responses in hematopoietic stem cells (HSCs), thereby enhancing blood cell production recovery.

22 Aug 2024

Ribonucleic acid for injection II enhances immunity and hematopoiesis in immunosuppressed mice

Announcing a new publication for Acta Materia Medica journal. Ribonucleic acid for injection II is a clinical adjuvant cancer therapy treatment based on immunotherapy, which exerts its effects by enhancing immune function and suppressing tumor growth.

16 Aug 2024

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Scientists from St. Jude Children's Research Hospital, Seattle Children's and the Children's Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

12 Aug 2024

$Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes$

Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes

Study indicates that older women with type 2 diabetes have a higher risk of fractures primarily due to impaired physical function rather than reduced bone density, despite stronger bone structure.

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

Understanding the age gap in leukemia survival rates

Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates over 85% compared to 50-75% in adults. Scientists at St. Jude Children's Research Hospital conducted a comprehensive study to understand the biological causes driving this difference. The work, published today in the Journal of Clinical Oncology, provides a blueprint for understanding B-cell acute lymphoblastic leukemia (B-ALL), the most common form of the disease.

7 Aug 2024

Bone Marrow News and Research

Further Reading

UK’s first robotic genomic testing facility for cancer patients launches

Cancer drug offers life-changing results for severe lupus patient

Early cholesterol spikes fuel atherosclerosis by altering macrophages

Aging immune system fuels cancer growth

Study links monoclonal B-cell lymphocytosis to elevated melanoma risk

Investigating inflammatory memory in hematopoietic stem cells within the AML niche

Study links periodontal bacteria to worsening rheumatoid arthritis

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Benefits of less intensive stem cell transplants for sickle cell disease

Research unveils how HMGA2 regulates stress responses in stem cells

Ribonucleic acid for injection II enhances immunity and hematopoiesis in immunosuppressed mice

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Poor physical function, not bone density, drives higher fracture risk in older women with type 2 diabetes

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

Understanding the age gap in leukemia survival rates

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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