Bone Mineral Density News and Research

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Largest ever Canadian study on osteoporosis informs health policy

Dr David Goltzman and his team from the Research Institute of the McGill University Health Centre (RI MUHC) and McGill University - along with colleagues from across Canada - have issued new recommendations to public health authorities about how to best cope with osteoporosis, a bone disease which leads to increased risk of fracture, particularly in the elderly.

16 Jun 2008

Potential hypophosphatasia therapy discovered

Researchers at the Burnham Institute for Medical Research, led by José Luis Millán, Ph.D., have demonstrated in mice the first successful use of enzyme replacement therapy to prevent hypophosphatasia (HPP), a primary skeletal disease of genetic origin. This discovery lays the foundation for future clinical trials for HPP patients.

1 Jun 2008

Epilepsy drug phenytoin causes bone loss in young women

Young women who took the commonly used epilepsy drug phenytoin for one year showed significant bone loss compared to women taking other epilepsy drugs, according to a study published in the April 29, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

28 Apr 2008

FDA approves Actonel (risedronate sodium) for postmenopausal osteoporosis

The U.S. Food and Drug Administration (FDA) approved a new once-a-month dose (150 mg) of Actonel (risedronate sodium) tablets for the treatment and prevention of postmenopausal osteoporosis. Actonel is approved to reduce the risk of fractures in postmenopausal women with osteoporosis.

24 Apr 2008

Loop diuretics linked to bone loss in older men

Older men who take loop diuretics, commonly prescribed drugs for heart failure and hypertension, appear to have increased rates of hip bone loss than men who are not taking this medication, according to a report in the April 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Apr 2008

The effect of Raloxifene treatment in postmenopausal women with chronic kidney disease

The osteoporosis drug raloxifene increases bone mineral density and reduces the risk of vertebral fractures among postmenopausal women with mild to moderate chronic kidney disease (CKD), according to a study appearing in the July 2008 issue of the Journal of the American Society Nephrology.

10 Apr 2008

Testosterone replacement theraphy for senior men beneficial

The risk of osteoporosis (bone fracture) in women is highly recognized by the public.

8 Apr 2008

Health effects of drinking tea

Tea drinkers who opt for black, oolong, green or white teas may find that these beverages offer health benefits.

3 Apr 2008

$Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density$

Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density

Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.

19 Mar 2008

Observational study of severe osteoporosis

Women who do not comply with treatment instructions for osteoporosis or who do not respond to treatment are more likely to suffer further fractures, which seriously affects their quality of life.

11 Mar 2008

$On-line fracture risk calculator$

On-line fracture risk calculator

It will soon be possible for anyone over 60 to predict their individual risk of bone fracture with the aid of a simple web-based tool, developed by the Sydney-based Garvan Institute of Medical Research.

10 Mar 2008

Bone problems and cystic fibrosis

A recent study by Dr Christina Haston, a researcher of the McGill University Health Centre research Institute, sheds some new light on the bone problems that generally accompany cystic fibrosis.

8 Feb 2008

Bone mineral content continues to increase in obese adolescents during weight loss

Obese teenagers who succeeded in losing weight in a year-long medically supervised weight control program also saw their bone mineral content increase over that period, say researchers from The Children's Hospital of Philadelphia.

5 Feb 2008

FDA approves only once-daily inhaled corticosteroid for children

Schering-Plough Corporation has announced that the U.S. Food and Drug Administration (FDA) has approved ASMANEX TWISTHALER 110 mcg (mometasone furoate inhalation powder) for the maintenance treatment of asthma as a preventive therapy in patients 4 to 11 years of age.

4 Feb 2008

$Risk of falling is overlooked as the major cause of fractures in the elderly$

Risk of falling is overlooked as the major cause of fractures in the elderly

An elderly person's risk of falling is too often overlooked when trying to prevent them from getting serious fractures, for instance of the hip or wrist, according to an article published in this week's BMJ.

21 Jan 2008

Calcium and vitamin D is more effective than calcium alone in preventing bone loss in elderly women

Previous studies have shown that high calcium intake can help prevent bone loss. This latest study, however, demonstrated that calcium therapy, although initially successful at preventing bone loss, was no different from placebo after three or five years.

18 Jan 2008

Testosterone supplementation in older men

Older men with low testosterone levels who received testosterone supplementation increased lean body mass and decreased body fat, but were no stronger and had no improvement in mobility or cognition compared with men who did not use the supplement, according to a study in the January 2 issue of JAMA.

2 Jan 2008

$Osteoporosis in women - previous vertebral fracture equals increased long-term risk for new fracture$

Osteoporosis in women - previous vertebral fracture equals increased long-term risk for new fracture

Over a 15 year period, women with low bone mineral density and a previous vertebral fracture had an increased risk of a new vertebral fracture compared to women with normal bone mineral density and no previous fracture, according to a study in the December 19 issue of JAMA.

20 Dec 2007

$Bone mineral density test predicts 'silent' spinal fractures years later$

Bone mineral density test predicts 'silent' spinal fractures years later

A single bone mineral density (BMD) test given 15 years earlier predicted a woman's risk of developing fractures to her spine over time, according to the largest and longest prospective study of osteoporosis.

20 Dec 2007

Early results show promise in reducing side effects from anastrozole

A common osteoporosis drug can shield women against the loss of bone mineral density - a side effect of the drug anastrozole which is taken to prevent breast cancer in the IBIS-2 study - according to new data presented at the San Antonio Breast Cancer Symposium.

14 Dec 2007