Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Nutlin-3a molecules stimulate signal to induce cell death and senescence in brain cancer

Researchers of Apoptosis and Cancer Group of the Bellvitge Biomedical Research Institute (IDIBELL) have found that a small molecule, Nutlin-3a, an antagonist of MDM2 protein, stimulates the signalling pathway of another protein, p53.

21 Apr 2011

Stanford and SanBio initiate SB623 Phase 1/2a clinical trial for stroke disability

The Stanford University School of Medicine and SanBio Inc. today announced the initiation of a Phase 1/2a clinical trial testing the safety and efficacy of a novel allogeneic cell therapy product, SB623, on patients suffering from stable deficits resulting from previous stroke injuries.

21 Apr 2011

Scientists discover critical pathway in the brain linked to stress response

A team of neuroscientists at the University of Leicester, UK, in collaboration with researchers from Poland and Japan, has announced a breakthrough in the understanding of the 'brain chemistry' that triggers our response to highly stressful and traumatic events.

21 Apr 2011

Abuse during childhood substantially increases risk of depression in adolescence

Queen's University professor Kate Harkness has found that a history of physical, sexual or emotional abuse in childhood substantially increases the risk of depression in adolescence by altering a person's neuroendocrine response to stress.

21 Apr 2011

Military personnel with TBI should receive adequate protein and calories immediately after trauma

To help alleviate the effects of severe traumatic brain injury (TBI), the U.S. Department of Defense should ensure that all military personnel with this type of injury receive adequate protein and calories immediately after the trauma and through the first two weeks of treatment, says a new report from the Institute of Medicine.

21 Apr 2011

Scientists discover 'small molecule' substance that blocks cholesterol formation in the brain

A needle-in-the-haystack search through nearly 390,000 chemical compounds had led scientists to a substance that can sneak through the protective barrier surrounding the brain with effects promising for new drugs for Parkinson's and Huntington's disease. They report on the substance, which blocks formation of cholesterol in the brain, in the journal, ACS Chemical Biology.

21 Apr 2011

Early musical study may provide cognitive benefits as we age

Those childhood music lessons could pay off decades later - even for those who no longer play an instrument - by keeping the mind sharper as people age, according to a preliminary study published by the American Psychological Association.

21 Apr 2011

Neuralstem signs MoU with BaYi Brain Hospital for ischemic stroke program in China

Neuralstem, Inc. (NYSE Amex: CUR) announced it has signed a Memorandum of Understanding with BaYi Brain Hospital in Beijing, China.

21 Apr 2011

Number of stressful events experienced during pregnancy linked to child behaviour outcomes

Research from Perth's Telethon Institute for Child Health Research has found a link between the number of stressful events experienced during pregnancy and increased risk of behavioural problems in children.

21 Apr 2011

New survey: Breastfeeding mothers show greater response to their infant's cry

A new study from The Journal of Child Psychology and Psychiatry finds that mothers who feed their babies breast milk exclusively, as opposed to formula, are more likely to bond emotionally with their child during the first few months after delivery.

21 Apr 2011

Prenatal exposure to organophosphate pesticides linked to lower IQ in children

In a new study suggesting pesticides may be associated with the health and development of children, researchers at the University of California, Berkeley's School of Public Health have found that prenatal exposure to organophosphate pesticides - widely used on food crops - is related to lower intelligence scores at age 7.

21 Apr 2011

Mindfulness meditation may help make decisions rationally rather than emotionally

If a friend or relative won $100 and then offered you a few dollars, would you accept this windfall? The logical answer would seem to be, sure, why not? "But human decision making does not always appear rational," said Read Montague, professor of physics at Virginia Tech and director of the Human Neuroimaging Laboratory at the Virginia Tech Carilion Research Institute.

21 Apr 2011

Brain trauma helped by nutrition

According to a report by the Institute of Medicine, military personnel who suffer traumatic brain injury need to be fed adequately and immediately to reduce the severity of trauma and improve their chance of survival. This finding has implications for people sustaining head injuries in other situations, such as sports and traffic accidents.

20 Apr 2011

Stealth Peptides launches mitochondrion targeting compound Bendavia at Experimental Biology 2011

Stealth Peptides Inc., a privately held biopharmaceutical company developing innovative mitochondrial therapies, introduced its lead clinical candidate, Bendavia™, a novel compound that targets the mitochondrion, during multiple scientific sessions of the Experimental Biology 2011 meeting.

20 Apr 2011

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

In the first animal model of Amyotrophic Lateral Sclerosis (ALS), developed by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, Dr. Pandey's lab has found in fruit flies that blocking the abnormal movement of a protein made by a mutated gene called FUS also blocks the disease process.

20 Apr 2011

New biosensor microchip with 'nanosensors' could simultaneously monitor thousands of protein-binding events

Stanford researchers have developed a new biosensor microchip that could significantly speed up the process of drug development. The microchips, packed with highly sensitive "nanosensors," analyze how proteins bind to one another, a critical step for evaluating the effectiveness and possible side effects of a potential medication.

20 Apr 2011

Researchers discover new way to force cancer cells to self-destruct

Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called TRAIL, also currently in clinical development as part of an anticancer regimen.

20 Apr 2011

Minimizing neurological side effects in high-grade glioma patients may improve survival

Minimizing neurological side effects in patients with high-grade glioma from chemoradiation may result in improved patient survival, a new study from radiation oncologists at the Kimmel Cancer Center at Jefferson suggests. These findings were reported in the April issue of the British Journal of Cancer.

20 Apr 2011

Spanish tool measures infant pain rapidly and simply

It turns out to be difficult to find out exactly how much a child who cannot yet speak suffers after a surgical operation. Researchers at the University Hospital of La Paz, in Madrid, have validated the 'Llanto' scale, the first, and only, tool in Spanish which measures infant pain rapidly and simply.

20 Apr 2011

RCSI conducts study to examine psychiatric disorders in people with epilepsy

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital, Dublin, have conducted the first study of its kind to examine in detail, the basis of psychiatric disorders which occur in people with epilepsy.

20 Apr 2011

Brain News and Research

Further Reading

Nutlin-3a molecules stimulate signal to induce cell death and senescence in brain cancer

Stanford and SanBio initiate SB623 Phase 1/2a clinical trial for stroke disability

Scientists discover critical pathway in the brain linked to stress response

Abuse during childhood substantially increases risk of depression in adolescence

Military personnel with TBI should receive adequate protein and calories immediately after trauma

Scientists discover 'small molecule' substance that blocks cholesterol formation in the brain

Early musical study may provide cognitive benefits as we age

Neuralstem signs MoU with BaYi Brain Hospital for ischemic stroke program in China

Number of stressful events experienced during pregnancy linked to child behaviour outcomes

New survey: Breastfeeding mothers show greater response to their infant's cry

Prenatal exposure to organophosphate pesticides linked to lower IQ in children

Mindfulness meditation may help make decisions rationally rather than emotionally

Brain trauma helped by nutrition

Stealth Peptides launches mitochondrion targeting compound Bendavia at Experimental Biology 2011

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

New biosensor microchip with 'nanosensors' could simultaneously monitor thousands of protein-binding events

Researchers discover new way to force cancer cells to self-destruct

Minimizing neurological side effects in high-grade glioma patients may improve survival

Spanish tool measures infant pain rapidly and simply

RCSI conducts study to examine psychiatric disorders in people with epilepsy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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