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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Acute neurological toxicity associated with chronic neurological toxicity in patients with high-grade gliomas

Patients with high-grade gliomas who experience acute (early) neurological toxicity during their treatment were more likely to experience chronic (late) neurological toxicity and shortened overall survival, according to researchers from the Kimmel Cancer Center at Jefferson. The study will be presented at the 2010 ASCO Annual Meeting in Chicago (Abstract #2037).

5 Jun 2010

HHF to open Terni Human Health Bioscience Institute

The Human Health Foundation, a nonprofit organization founded in 2006 to develop and fund biomedical research in Italy, will open the Terni Human Health Bioscience Institute for the investigation of breast, brain and lung cancer on June 7th in Terni, Italy.

5 Jun 2010

VA partners with National Institutes of Health to research on Parkinson's disease

Veterans and others with Parkinson's disease who undergo deep brain stimulation may benefit from research co-sponsored by the Department of Veterans Affairs and published recently in the prestigious New England Journal of Medicine.

5 Jun 2010

High frequency ventilation for preterm babies just as effective

A University of Sydney study of ventilation strategies has shown that high-frequency oscillatory ventilation (HFOV) for preterm babies gives the same outcomes as conventional ventilation (CV).

4 Jun 2010

Antiemetic-regimen with fosaprepitant injection provides similar protection against CINV as oral EMEND

Merck announced today results from a new non-inferiority trial of an antiemetic regimen containing fosaprepitant dimeglumine administered as a single intravenous (IV) 150-mg dose in combination with a 5-HT3 antagonist and dexamethasone compared with a three-day regimen of aprepitant with a 5-HT3 antagonist and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients receiving a first cycle of cisplatin-based chemotherapy.

4 Jun 2010

Researchers induce memory of safety in brain of rats

Researchers have found a way to pharmacologically induce a memory of safety in the brain of rats, mimicking the effect of training. The finding suggests possibilities for new treatments for individuals suffering from anxiety disorders.

4 Jun 2010

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

A Johns Hopkins and Japanese research team has generated the first comprehensive genetic "parts" list of a mouse hypothalamus, an enigmatic region of the brain — roughly cherry-sized, in humans — that controls hunger, thirst, fatigue, body temperature, wake-sleep cycles and links the central nervous system to control of hormone levels.

4 Jun 2010

ASTRO to honor David Larson and William McBride with prestigious Gold Medal award

David Larson, M.D., Ph.D., FASTRO, and William McBride, D.Sc., Ph.D., have been chosen to receive the American Society for Radiation Oncology's most prestigious award, the Gold Medal. They will be presented with this honor at the Awards Ceremony during ASTRO's 52nd Annual Meeting, taking place October 31 to November 4, 2010, in San Diego.

4 Jun 2010

Novel brain mechanism promises new and effective anesthetics

A brain mechanism involved in both dreaming and waking from sleep may hold the key to new, more effective anesthetics and stimulants, reported neuroscientists at the University of Arkansas for Medical Sciences (UAMS).

4 Jun 2010

Study: Rash adolescent behaviors tied to biological motivations

There are biological motivations behind the stereotypically poor decisions and risky behavior associated with adolescence, new research from a University of Texas at Austin psychologist reveals.

4 Jun 2010

Study of methylphenidate for cancer-related fatigue benefits patients with stage III/IV disease

Cancer-related fatigue is often a major problem for cancer patients, beginning at diagnosis, during treatment and after completing therapy. Researchers at Mayo Clinic and the North Central Cancer Treatment Group (NCCTG) recently completed a study testing methylphenidate in the treatment of cancer-related fatigue and found that, while it did not improve fatigue for a broad group of patients, the data did not rule out a benefit for those with stage III/IV cancer.

4 Jun 2010

Oxycyte perfluorocarbon emulsion demonstrates marked neuroprotective effect in rat model of spinal cord injury

Oxygen Biotherapeutics, Inc. today reported on the results of two University of Miami Miller School of Medicine studies involving the Company's third-generation perfluorocarbon, Oxycyte® perfluorocarbon emulsion. Both study reports showed that Oxycyte® has a marked neuroprotective effect in a rat model of spinal cord injury.

4 Jun 2010

Study confirms Azilect as a selective MAO-B inhibitor

Teva Neuroscience Inc. today announced the publication of a study demonstrating the selectivity of Azilect® (rasagiline tablets) for inhibition of MAO-B (monoamine oxidase-B) at the maximum approved dose of 1 mg/day. The data was published in the Journal of Clinical Pharmacology OnlineFirst on May 5, 2010.

4 Jun 2010

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

The liver scarring of α1-antitrypsin deficiency, the most common genetic cause for which children undergo liver transplantation, might be reversed or prevented with a medication that has long been used to treat seizures, according to findings from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine that will published in Science and are available online today through the Science Express website.

4 Jun 2010

Researchers find a way to isolate pancreatic islet cells from brain dead donors using DI

A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection, a process that immediately cools donor islet cells at the injection site.

4 Jun 2010

St. Jude receives top spot in 2010-11 Best Children's Hospital rankings

St. Jude Children's Research Hospital has been named the nation's top children's cancer hospital in the 2010-11 Best Children's Hospital rankings published in U.S. News & World Report. St. Jude received the best overall score summarizing quality of care. St. Jude is the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children and serves as an international resource to physicians and researchers.

4 Jun 2010

Research finding suggests possibilities for future treatment of anxiety disorders

Researchers at the University of Puerto Rico, School of Medicine have found a way to pharmacologically induce a memory of safety in the brain of rats. As reported in the June, 4 2010 issue of Science, administering brain-derived neurotrophic factor into the prefrontal cortex prevented rats from expressing fear to a tone that had been previously paired with a shock.

4 Jun 2010

State roundup: Health law could be critical for Miss.'s poor; Colorado passes end-of-life care laws, Penn. details plan for high risk pool

The health care overhaul, which "provides hundreds of billions of dollars to help states expand medical insurance for the poor," could prove critical for Mississippi, which "has the highest poverty rate in the nation and some of the sickest people, with the country's highest rate of heart disease and the second-highest rate of diabetes.

4 Jun 2010

WisTa Laboratories announces collaborative R&D agreement with Bayer Schering Pharma

WisTa Laboratories Ltd, a wholly owned subsidiary of TauRx Pharmaceuticals, announced today that they have entered a collaborative R&D agreement with Bayer Schering Pharma AG, Germany, which could redefine the way Alzheimer's disease (AD) and related disorders are currently being diagnosed and treated.

4 Jun 2010

Intellect Neurosciences receives USPTO Notice of Allowance for IN-N01 monoclonal antibody patent

Intellect Neurosciences, Inc. announced today that it has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for a new patent related to the Company's humanized monoclonal antibody, IN-N01, being developed as a disease-modifying treatment for Alzheimer's disease and other related indications.

4 Jun 2010

Brain News and Research

Further Reading

Acute neurological toxicity associated with chronic neurological toxicity in patients with high-grade gliomas

HHF to open Terni Human Health Bioscience Institute

VA partners with National Institutes of Health to research on Parkinson's disease

High frequency ventilation for preterm babies just as effective

Antiemetic-regimen with fosaprepitant injection provides similar protection against CINV as oral EMEND

Researchers induce memory of safety in brain of rats

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

ASTRO to honor David Larson and William McBride with prestigious Gold Medal award

Novel brain mechanism promises new and effective anesthetics

Study: Rash adolescent behaviors tied to biological motivations

Study of methylphenidate for cancer-related fatigue benefits patients with stage III/IV disease

Oxycyte perfluorocarbon emulsion demonstrates marked neuroprotective effect in rat model of spinal cord injury

Study confirms Azilect as a selective MAO-B inhibitor

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

Researchers find a way to isolate pancreatic islet cells from brain dead donors using DI

St. Jude receives top spot in 2010-11 Best Children's Hospital rankings

Research finding suggests possibilities for future treatment of anxiety disorders

State roundup: Health law could be critical for Miss.'s poor; Colorado passes end-of-life care laws, Penn. details plan for high risk pool

WisTa Laboratories announces collaborative R&D agreement with Bayer Schering Pharma

Intellect Neurosciences receives USPTO Notice of Allowance for IN-N01 monoclonal antibody patent

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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