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Potential new treatment for Huntington and Parkinson patients

A potential new treatment for neurodegenerative disorders, which seems to be able to reduce the toxic protein aggregates characteristic of many of these diseases, is published online this week in the journal Proceedings of the National Academy of Sciences.

7 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Extensive study of natalizumab

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

7 Mar 2006

Concerta used to treat ADHD may be less likely to be abused than other stimulant drugs

A team led by Massachusetts General Hospital (MGH) researchers has found that a delayed-release stimulant used to treat attention-deficit hyperactivity disorder (ADHD) may be less likely to be abused than other stimulant drugs.

1 Mar 2006

Study provides new evidence of the importance of reward pathways in the brain

Deleting a specific gene in the brain has the same effect that antidepressants do in mice that have been conditioned to be depressed, report researchers at UT Southwestern Medical Center.

24 Feb 2006

Monoclonal antibody targets key tumor growth factor

Monoclonal antibody targets key tumor growth factor; Successfully causes brain tumor regression and improves animal survival

19 Feb 2006

Tetrabenazine cuts down involuntary movements in Huntington's disease

The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement, according to a study in the February 14 issue of the journal Neurology.

17 Feb 2006

Scientists map brain area that may help find human brain stem cells

A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells.

17 Feb 2006

Researchers develop way to visualize synchronized interactions of nerve cells in the brain

Researchers at the University of Minnesota Medical School and the Brain Sciences Center at the Minneapolis VA Medical Center have discovered a new way to assess how brain networks act together.

16 Feb 2006

Mystery of cot death may be explained

A failure to 'gasp' has long been proposed as the basis for sudden infant death syndrome, or cot death. A team at the University of Bristol has discovered a subset of cells in the brain that have the ability to self-generate nervous impulses, which appear essential for gasping. These cells have been termed 'pacemakers'.

16 Feb 2006

Research may help explain Alzheimer's memory loss

Based on laboratory research, scientists at Georgetown University Medical Center have a new theory as to why people with Alzheimer's disease have trouble performing even the simplest memory tasks, such as remembering a family member's name.

16 Feb 2006

Potential universal strategy for treating drug addiction

An international research team led by the University of Saskatchewan has discovered a signaling pathway in the brain involved in drug addiction, together with a method for blocking its action, that may point to a single treatment strategy for most addictions.

14 Feb 2006

Gene therapy cures depressed mice

Researchers in the U.S. say that deleting a specific gene in the brain of mice that have been conditioned to be depressed, has the same effect as antidepressants.

13 Feb 2006

Hormone discovered in bird brains also plays major role in mammalian reproductive system

University of California, Berkeley, researchers have discovered a new actor in the mammalian reproductive system, a hormone that fills a role long suspected, but until now undetected.

7 Feb 2006

Abraham Lincoln may have suffered from movement disorder

Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum-- the part of the brain that controls movement.

7 Feb 2006

Breakthrough in lupus research

A major breakthrough in lupus research - one that may fundamentally change thinking on how the disease affects behavior and cognition - was reported in the January 17, 2006 Proceedings of the National Academy of Sciences (PNAS).

25 Jan 2006

Novel compound stops brain cell degeneration in Alzheimer's disease

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

22 Jan 2006

New microRNA mechanism for regulating brain function

Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity. Among those elements are microRNAs, tiny, recently discovered RNA molecules that suppress gene expression.

18 Jan 2006

First potential treatment for intracerebral hemorrhage

The first potential treatment for strokes that result from bleeding in the brain is under study at the Medical College of Georgia.

18 Jan 2006

Mental illness linked to diet

According to new research released this week, mental health is linked to diet and changes to diets over the last 50 years may hold the key to the rise of mental illness.

17 Jan 2006