Brain Disease News and Research

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All football players do not get chronic traumatic encephalopathy

Preliminary results from the first four brains donated to the Canadian Sports Concussion Project at the Krembil Neuroscience Centre, TorontoWesternHospital, reveal that two of the four former Canadian Football League (CFL) players suffered from a brain disease known as Chronic Traumatic Encephalopathy (CTE), while two did not show signs of CTE.

27 Jul 2011

Alzheimer’s risk reduced by healthy living: study

According to a new study leading a healthy lifestyle can help prevent Alzheimer's disease. Researchers said at Alzheimer's Association International Conference in Paris on Tuesday that the number of Alzheimer's cases could be cut in half if people exercise, eat well and stop smoking. Other risks include depression, high blood pressure, diabetes and obesity. Education is also a factor, because illiteracy keeps brains from developing properly. The new findings have been published in the journal Lancet Neurology.

20 Jul 2011

Earlier Alzheimer’s disease and dementia diagnosis: New guidelines

It has been the tradition to confirm the presence of Alzheimer's disease during autopsy. However new guidelines proposed on Sunday by the U.S. National Institute on Aging and the Alzheimer's Association seek to distinguish between memory changes or dementia diagnosed by doctors when people are alive, and the changes pathologists can see in an autopsy.

18 Jul 2011

Amyloid peptide Aβ43 may serve as biomarker for diagnosis of Alzheimer's

Researchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease.

4 Jul 2011

Gene overexpression linked with Alzheimer's disease and Down syndrome

Chronic stress has long been linked with neurodegeneration. Scientists at USC now think they may know why.

29 Jun 2011

Early stages of Alzheimer’s difficult to detect: Study

According to a new study, more than half of people who develop Alzheimer's disease before the age of 60 are initially misdiagnosed as having other kinds of brain disease when they do not have memory problems. The research is published in the May 17, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

17 May 2011

Imec, VIB and KU Leuven join forces in pioneering brain research at NERF and in the Human Brain Project

Today, Flanders' ambitious brain research that may lead to better diagnosis and treatment of brain disease, new prosthesis technologies for patients with a disability, a new generation of more intelligent robots, etc. switches into higher gear. In the presence of Ingrid Lieten, Flemish Minister of Innovation, Public Procurement, the Media and Combatting Poverty, imec, VIB and K.U.Leuven officially inaugurated the NERF (Neuro-Electronics Research Flanders) labs on the Imec campus in Leuven. The Human Brain Project was also launched on this occasion, one of the projects on the shortlist of the prestigious European Flagship Programme. Through NERF and the participation of Flanders' research institutes in the Human Brain Project, Flanders shows that it is putting progressive brain research high on its research agenda.

16 May 2011

Mithridion's MCD-386CR receives Orphan Drug designation from FDA for PSP treatment

Mithridion, Inc., a privately-owned clinical stage drug development company focusing on serious Central Nervous System disorders, announces that the U.S. Food and Drug Administration has awarded Orphan Drug designation for MCD-386CR, its lead drug candidate, for the treatment of Progressive Supranuclear Palsy.

9 May 2011

Brain function variations may increase person's risk of drug abuse

One can look at drug addiction as a moral issue, a social ill, or a criminal problem. But Lynn Oswald's experience studying the neuroscience of addiction tells her that it is something else entirely: a disease of the brain.

30 Apr 2011

Experts to teach athletic trainers, medical providers on sports head injuries

Top experts from around the country will be at the University of North Carolina at Chapel Hill later this week to teach athletic trainers and medical providers how to prevent deaths and serious injuries among high school and college athletes.

28 Apr 2011

Researchers study role of acetylation in Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes associated with Alzheimer's disease and related disorders. The findings were published in the latest issue of Nature Communications.

1 Apr 2011

Welsh CJD alert after two years of exposure

Thirty-eight people have been told they may have been put at risk of contracting the fatal brain disease Creutzfeldt-Jakob disease (CJD) following surgery. All the patients were operated on between 2007 and 2009 at either Swansea's Morriston or Singleton hospital, Neath Port Talbot or Princess of Wales Hospital in Bridgend.

29 Mar 2011

Early symptoms of Parkinson's disease may be revealed in dream sleep

During a large-scale study of the socioeconomic costs of this neurodegenerative disease, Danish researchers, some from the University of Copenhagen, discovered that very early symptoms of Parkinson's disease may be revealed in dream or REM sleep.

28 Mar 2011

Baby Joseph’s flight to US from Canada

Baby Joseph Maraachli all of one year of age, is in a vegetative state with a severe neurological condition and will not recover, Canadian doctors say. His parents Moe Maraachli and Sana Nader, have transferred him to a US Catholic hospital after an Ontario court ruled doctors could remove a breathing tube keeping him alive. An Ontario hospital had refused his parents' request for a tracheotomy they say will prolong his life by six months and allow him to die at home. A Catholic hospital in the US city of St Louis will review his case, according to the family’s lawyer.

14 Mar 2011

Nanotechnology might provide greater efficacy of medicines for brain disease

Technology has been developed within Top Institute Pharma that helps medicines be absorbed quicker into the blood and thus be more effective. Researcher Hans de Waard, who is associated with the University of Groningen, will obtain his doctorate on this subject on March 11. De Waard: "Many current medicines are not easily dissolved in the digestive tract, which means that they barely reach the bloodstream.

14 Mar 2011

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

Therapeutic potential of iPS cells may be limited by reprogramming errors and genomic instability

In the past few months, a slew of papers have indicated that the therapeutic potential of a promising type of stem cell, called induced pluripotent stem (iPS) cells, might be limited by reprogramming errors and genomic instability. iPS cells are engineered by reprogramming fully differentiated adult cells, often skin cells, back to a primitive, embryonic-like state.

9 Mar 2011

Longer looks: Best health policy picks from thought-provoking publications

Every Thursday, KHN's Jessica Marcy compiles this selection of interesting perspectives, from a variety of publications, on health care in America.

4 Mar 2011

Boston Blades' new team to raise money, awareness for Alzheimer's research

The Alzheimer's Association, Massachusetts/New Hampshire Chapter and the exciting new women's hockey team, the Boston Blades, announced they are teaming up to raise money and awareness for Alzheimer's research.

4 Mar 2011

Special issue of Neuron journal provides new insight into recent advances in addiction research

Addiction is a brain disease that destroys lives, devastates families and tears at the very fabric of society. Effective prevention and treatment of addiction requires a clear understanding of the complex brain mechanisms that underlie addictive behaviors, and research has provided a fascinating view of how substance abuse hijacks neuronal circuits involved in reward and motivation and causes profound and persistent changes in behavior.

24 Feb 2011