Bronchopulmonary Dysplasia News and Research

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Investigational protein replacement protects neonatal mice from deadly intestinal disease

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues found that an investigational protein replacement – recombinant human insulin-like growth factor 1 and its binding protein-3 (rhIGF-1/BP3) – protected neonatal mice from necrotizing enterocolitis (NEC), a deadly intestinal disease that often strikes extremely premature infants.

28 Feb 2024

Study identifies key factor in lung and eye damage in preemies

Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing.

11 Dec 2023

Effects of using race and ethnicity in clinical algorithms in health care systems

A Special Issue of the peer-reviewed journal Health Equity focuses attention on the incorrect use of race and ethnicity in clinical algorithms in health care systems across the U.S. and internationally. The Special Issue is titled "Race Adjustment in Clinical Algorithms and Other Clinical Decision-making Tools."

4 Dec 2023

Is the increased risk of bronchopulmonary dysplasia from high-dose docosahexaenoic acid supplementation in the neonatal period associated with changes to IQ?

Study analyzed whether a reduction in IQ benefit was associated with the increased risk of BPD with DHA supplementation.

13 Jun 2023

Preterm birth linked to elevated risk of asthma or COPD in adulthood

Breathing problems are among the most common problems that babies born preterm have after birth. A new study of over 2.6 million people from Finland and Norway shows that such problems may extend at least up to middle age.

30 Mar 2023

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model for guiding immunization and prophylactic treatment of one-year-old infants against RSV infections.

3 Mar 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Study reveals the heavy burden of RSV among healthy infants

A new study in The Lancet Respiratory Medicine journal aimed to determine hospitalized and medically-attended RSV-associated respiratory infections in healthy infants across Europe.

14 Nov 2022

Antenatal steroid therapy for pregnant women may improve survival among extremely preterm infants

Steroid treatment before birth appears to improve survival and reduce complications among extremely preterm infants, according to a study funded by the National Institutes of Health.

26 Sep 2022

Noninvasive respiratory support may not benefit nano-preterm infants, study suggests

Extremely premature infants still face daunting risks of sickness or death, even though advances in neonatal-perinatal care have improved infant survival at progressively lower gestational ages. Bronchopulmonary dysplasia -; a serious condition of undeveloped lungs -; is a leading morbidity in these tiny infants.

6 Sep 2022

Attending daycare may increase lung complications in preterm children with bronchopulmonary dysplasia

Attending daycare in the first three years of life is linked with an increase in lung complications in children who were born prematurely and diagnosed with a form of chronic lung disease, according to new research led by Children's Hospital of Philadelphia.

26 Jul 2022

Review may lead to improvements in therapeutic options for preterm infants

One in two premature babies receives transfusions of red blood cells (RBC) due to anemia. There are no generally accepted clinical guidelines for the degree of anemia necessitating blood transfusions.

26 Jul 2022

Fortified breastmilk does not influence IQ in preterm infants

Scientists compare the cognitive and psychological development of preterm infants who were breastfed with or without fortification.

13 Jul 2022

Subgroups of preterm born children can be distinguished with distinct outcome profiles, study reports

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that, among very preterm born children, subgroups can be distinguished with distinct outcome profiles that vary in severity, type, and combinations of deficits.

28 Jun 2022

Bronchopulmonary Dysplasia News and Research

Investigational protein replacement protects neonatal mice from deadly intestinal disease

Study identifies key factor in lung and eye damage in preemies

Effects of using race and ethnicity in clinical algorithms in health care systems

Is the increased risk of bronchopulmonary dysplasia from high-dose docosahexaenoic acid supplementation in the neonatal period associated with changes to IQ?

Preterm birth linked to elevated risk of asthma or COPD in adulthood

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Study reveals the heavy burden of RSV among healthy infants

Antenatal steroid therapy for pregnant women may improve survival among extremely preterm infants

Noninvasive respiratory support may not benefit nano-preterm infants, study suggests

Attending daycare may increase lung complications in preterm children with bronchopulmonary dysplasia

Review may lead to improvements in therapeutic options for preterm infants

Fortified breastmilk does not influence IQ in preterm infants

Subgroups of preterm born children can be distinguished with distinct outcome profiles, study reports

Study assesses whether early targeted treatment of patent ductus arteriosus improves outcomes in extreme preterm babies

Researchers reveal possible way to treat newborns with rare genetic lung condition

Study identifies risk factors for severe COVID-19 in hospitalized children in Canada

Research provides a roadmap for new therapies to treat chorioamnionitis

Nanotherapies may benefit preterm babies with bronchopulmonary dysplasia

Hydrocortisone does not prevent bronchopulmonary dysplasia in preterm infants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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