Bupropion News and Research

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Watson Pharmaceuticals receives FDA approval for generic Wellbutrin XL

Watson Pharmaceuticals, Inc. has announced that its subsidiary, Watson Laboratories, Inc., has received final approval today from the United States Food and Drug Administration on its Abbreviated New Drug Application (ANDA) for Bupropion Hydrochloride Extended-Release Tablets (XL) in the 150 mg strength.

26 Nov 2008

32% of Americans nicotine dependent

Nicotine dependence has reached a 15-year high, with nearly 75 percent of people currently seeking tobacco-dependence treatment categorized as highly nicotine dependent. New research, presented at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians (ACCP), reports that nicotine dependence severity has increased 12 percent between 1989 and 2006, while the proportion of people classified as highly nicotine dependent has increased 32 percent.

28 Oct 2008

Actavis receives approval of generic Wellbutrin in U.S.

Actavis Group today announced that it has received approval from the U.S. Food & Drug Administration to market Bupropion Hydrochloride extended-release tablets (XL) 300mg. Distribution of the product will commence immediately.

18 Aug 2008

Chantix for smoking cessation performs better than placebos

Six treatments for smoking cessation perform better than placebos - including varenicline (Chantix), recently approved for use in Canada - states a team of researchers from McGill University and the University of Montreal in an article published in Canadian Medical Association Journal.

14 Jul 2008

Distinct clusters of genetic markers linked to treatment responses for smoking cessation

Scientists have identified distinct clusters of genetic markers associated with the likelihood of success or failure of two smoking cessation treatments, nicotine replacement therapy (NRT) and the medication bupropion (Zyban). This study, supported by the National Institute on Drug Abuse (NIDA) and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), was published in the June issue of the journal Archives of General Psychiatry.

2 Jun 2008

Antidepressants might be worthless for treating low back pain

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

30 Jan 2008

FDA to review Champix/Chantix side effects

A drug which was designed to help people quit smoking is causing concern following a number of reports that it induces suicidal feelings and aggressive and erratic behaviour.

29 Nov 2007

Fear of gaining weight and smoking cessation in women

Is a fear of getting fatter partly to blame for the fact that nearly one in five American women still smokes, and many don't try to quit"

6 Nov 2007

Bupropion plus counseling appears to help adolescents quit cigarette smoking in the short term

Almost one-fourth of U.S. high school students currently smoke cigarettes, according to background information in the article. Many teen smokers want to quit, but studies estimate that only about 4 percent of those who try are successful each year.

6 Nov 2007

Orexigen presents findings on obesity drug candidates

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of central nervous system (CNS) disorders including obesity, has presented the results of a preclinical study that further supports the Company's understanding of an aspect of the mechanism of action of Contrave, one of its two late-stage obesity drug candidates.

24 Oct 2007

Why some people find it so difficult to stop smoking

Mark Twain boasted that it was easy to quit smoking because he did it every day.

24 Sep 2007

Genetic variation affects smoking cessation treatment

Mark Twain boasted that it was easy to quit smoking because he did it every day.

21 Sep 2007

Smoking-cessation may be in the genes

Whether a smoking-cessation drug will enable you to quit smoking may depend on your genes, according to new genotyping research from the Centre for Addiction and Mental Health (CAMH).

18 Sep 2007

Link between genetic variant and effectiveness of smoking cessation meds

A genetic variant present in nearly half of Americans of European ancestry is linked to greater effectiveness of the smoking cessation medication bupropion (Zyban), according to research by scientists supported by the National Institute on Drug Abuse (NIDA) and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

11 Sep 2007

Going in to hospital provides an opportunity to stop smoking

A Cochrane Systematic Review has found that the chance of successfully quitting can be enhanced if patients receive smoking cessation counselling during their stay, and then have at least one month of supportive contact after going home.

18 Jul 2007

Young adult smokers are highly motivated to quit

Despite tried and true methods to quit smoking, young adults do not take advantage of these proven smoking cessation treatments that can double their chances of quitting, University of Illinois at Chicago public health researchers report.

29 Jun 2007

Adding medication improves recovery for elderly with depression

Adding a medication to a standard treatment regimen for major depressive disorder in the elderly improves chances of recovery in those who do not adequately respond to the first-course therapy or who relapse from it, finds a University of Pittsburgh School of Medicine study published in the June issue of the American Journal of Psychiatry, the official journal of the American Psychiatric Association.

3 Jun 2007

Less children and teens taking antidepressants

The number of children and teenagers prescribed antidepressant medications appears to have decreased following public warnings about suicidal behavior potentially associated with the drugs, according to a report published in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Apr 2007

Treatment options for bipolar disorder

For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine.

1 Apr 2007

Varenicline shown to help 'quit smoking'

A drug recently approved by the U.S. Food and Drug Administration as an aid to smoking cessation appears effective both short- and long-term for smokers trying to quit, according to two reports in the August 14/28 issue of the Archives of Internal Medicine.

14 Aug 2006