CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Aid agencies threaten to leave Afghanistan as President Karzai orders private security firms to dissolve

Companies and aid organizations implementing hundreds of millions of dollars in U.S.-funded projects here say they are preparing to leave Afghanistan unless President Hamid Karzai amends a decree that outlaws their private security protection, the Wall Street Journal reports.

25 Oct 2010

Arena's NDA receives Complete Response Letter for lorcaserin

Arena Pharmaceuticals, Inc. and Eisai Inc. announced that the US Food and Drug Administration (FDA) issued a Complete Response Letter (CRL) regarding Arena's New Drug Application (NDA) for lorcaserin. Lorcaserin is intended for weight management, including weight loss and maintenance of weight loss, in patients who are obese

25 Oct 2010

UHCMC improves workflow using Toshiba's suite of systems

One of the top priorities for healthcare facilities today is improving operational efficiency. To help address this issue, University Hospitals Case Medical Center (UHCMC) in Cleveland, Ohio, rated among the best hospitals in the nation, recently purchased a suite of systems from Toshiba America Medical Systems, Inc., including an Aplio MX, two Xario XGs and two Aplio XG systems.

21 Oct 2010

Endocrine Society's statement clarifies association between hormone therapy and breast cancer risk

Richard J. Santen, MD, lead author of The Endocrine Society's Scientific Statement on menopausal hormone therapy, can provide clarity on the association of hormone therapy and increased risk of breast cancer as reported in an article published this week in The Journal of the American Medical Association (JAMA)

21 Oct 2010

Cmed debuts Timaeus 5 unified eClinical platform and Timaeus HotSpot regulatory-compliant eClinical suite

Cmed Technology, an eClinical technology provider, today unveiled two product previews at two major pharmaceutical conferences. It debuted Timaeus 5, Cmed's newest version of its unified eClinical platform to manage data from Study Design through Reporting. Timaeus 5 adds enhanced usability, extended operational capabilities, streamlined investigator and monitor interaction, and expanded reporting capabilities.

18 Oct 2010

New insights into HIV infection process may allow antiviral drug development

New insights into the human immunodeficiency virus (HIV) infection process, which leads to acquired immunodeficiency syndrome (AIDS), may now be possible through a research method recently developed in part at the National Institute of Standards and Technology (NIST), where scientists have glimpsed an important protein molecule's behavior with unprecedented clarity.

15 Oct 2010

Role conflicts and high emotional demands increase risk of burnout in human service workers

For workers in human service settings, job factors like role conflicts and high emotional demands can increase the risk of burnout—leading to long-term sickness absence, reports a study in the September Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).

12 Oct 2010

LC Luxuries announces acquisition of domain name CannaCare.com

LC LUXURIES LIMITED today announced that it has acquired the domain name CannaCare.com and will begin developing CannaCare.com as its nationwide physician marketing engine as it relates to the cannabis industry. Development is underway and the Company anticipates the site operational by the end of the year. Bonni Goldstein, MD, a board member for LC Luxuries Limited, will be materially involved with the content and direction of CannaCare.com.

4 Oct 2010

AcelRx completes ARX-02 End-of-Phase 2 meeting with FDA for cancer breakthrough pain management system

AcelRx Pharmaceuticals, Inc. today announced that it has completed an End-of-Phase 2 meeting with the US Food and Drug Administration (FDA) for ARX-02, a proprietary Sufentanil NanoTab™ Breakthrough Pain Management System for the treatment of cancer breakthrough pain in opioid-tolerant patients. FDA reviewed a package based on the previously announced positive Phase 2 clinical study results to date for ARX-02 and provided AcelRx with guidance on the Phase 3 program design and NDA requirements.

1 Oct 2010

Disparities in cardiac care begin when patients arrive at hospital emergency rooms: Study

The well-documented disparities in cardiac care may begin almost as soon as patients arrive at hospital emergency rooms. In a study published in Academic Emergency Medicine, Massachusetts General Hospital researchers report that African-American and Hispanic patients assessed for chest pain were less likely than white patients to be categorized as requiring immediate care, despite a lack of significant differences in symptoms.

27 Sep 2010

Health law affecting insurers, employers and comparative effectiveness research

Kaiser Health News has a list of eight provisions in the new health law that took effect this week as insurers, businesses and employers sort out what the new changes mean for them.

27 Sep 2010

First Edition: September 24, 2010

In today's news, more reports regarding the health reform provisions that took effect yesterday and more details on the GOP's "Pledge To America."

24 Sep 2010

Six Chicago high school students win CAP's 2010 'Path to a Future in Medicine' award

The College of American Pathologists (CAP) awarded six Chicago high school students the College's 2010 "Path to a Future in Medicine" award.

24 Sep 2010

CAP meeting to highlight medical diagnostic procedures

New science in cancer, genetic testing, molecular diagnostics, medical ethics, and gender-based disorders will be featured topics when nearly 1,200 pathologists gather at the Hyatt Regency Chicago on September 26 - 29 for the annual scientific meeting of the College of American Pathologists (CAP).

24 Sep 2010

Opinions: MDGs

"The overarching and noble goal [of this week's Millennium Development Goal (MDG) summit in New York] is reducing global poverty. But the most compelling and achievable objectives - huge reductions in maternal and child mortality worldwide - will be severely undermined if the Obama administration either directly or covertly integrates abortion into the final outcome document," Rep. Chris Smith (R-N.J.) writes in a Washington Post opinion piece.

21 Sep 2010

Financial Times analyzes increasing pressures on aid groups to demonstrate accomplishments with donor money

Ahead of the U.N. Millennium Development Summit, the Financial Times' Alan Beattie analyzes the effects of tightening aid budgets on development program funding, emphasizing how such changes are resulting in a push for increased measures to assess the effectiveness of aid.

18 Sep 2010

ISTA Pharmaceuticals initiates REMURA Phase 3 clinical program for dry eye disease

ISTA Pharmaceuticals, Inc., today announced that it has initiated a Phase 3 clinical program of ISTA's proprietary formulation of REMURA (bromfenac ophthalmic solution for dry eye) for alleviating the signs and symptoms of dry eye disease. The Phase 3 efficacy studies are being conducted under a Special Protocol Assessment (SPA) agreed upon with the U.S. Food and Drug Administration (FDA).

16 Sep 2010

CRA appeals to FDA for name change allowance in high fructose corn syrup labeling

In an effort to help clarify the labeling of food products for consumers, the Corn Refiners Association (CRA) today petitioned the U.S. Food and Drug Administration (FDA) to allow manufacturers the option of using 'corn sugar' as an alternative name for high fructose corn syrup.

14 Sep 2010

Gates Foundation 2009 annual report released

The Bill & Melinda Gates Foundation on Tuesday released its 2009 annual report (.pdf) highlighting some of the foundation's work over the last year, the Puget Sound Business Journal reports (Holtzman, 9/7).

10 Sep 2010

Greater clarity on legal implications of testing incapacitated patients for blood-borne viruses needed

Anaesthetists are calling for greater clarity on the legal implications of testing incapacitated patients for blood-borne viruses, after a survey found that this is often done following staff needlestick injuries, in possible breach of UK legislation.

31 Aug 2010

CLARITY News and Research

Further Reading

Aid agencies threaten to leave Afghanistan as President Karzai orders private security firms to dissolve

Arena's NDA receives Complete Response Letter for lorcaserin

UHCMC improves workflow using Toshiba's suite of systems

Endocrine Society's statement clarifies association between hormone therapy and breast cancer risk

Cmed debuts Timaeus 5 unified eClinical platform and Timaeus HotSpot regulatory-compliant eClinical suite

New insights into HIV infection process may allow antiviral drug development

Role conflicts and high emotional demands increase risk of burnout in human service workers

LC Luxuries announces acquisition of domain name CannaCare.com

AcelRx completes ARX-02 End-of-Phase 2 meeting with FDA for cancer breakthrough pain management system

Disparities in cardiac care begin when patients arrive at hospital emergency rooms: Study

Health law affecting insurers, employers and comparative effectiveness research

First Edition: September 24, 2010

Six Chicago high school students win CAP's 2010 'Path to a Future in Medicine' award

CAP meeting to highlight medical diagnostic procedures

Opinions: MDGs

Financial Times analyzes increasing pressures on aid groups to demonstrate accomplishments with donor money

ISTA Pharmaceuticals initiates REMURA Phase 3 clinical program for dry eye disease

CRA appeals to FDA for name change allowance in high fructose corn syrup labeling

Gates Foundation 2009 annual report released

Greater clarity on legal implications of testing incapacitated patients for blood-borne viruses needed

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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