Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.
Scientists have provided new insights into how and why the brain is organised - knowledge which could eventually inform diagnosis of and treatments for conditions like Alzheimer's disease and autism.
Scientists have provided new insights into how the brain is organised - knowledge which could eventually inform diagnosis of and treatments for conditions like Alzheimer's disease and autism.
Research into Parkinson's Disease at the University of Dundee has received a boost from a fundraising campaign organised by the Falkirk Branch of the Parkinson's Disease Society.
Laboratory discoveries by scientists at two universities may lead to new directions in cancer therapy drugs. The researchers have discovered that a genetic switch involved in growth and development of an animal is the same one used to prevent normal cells from becoming cancerous.
New evidence in Cell Metabolism reveals a molecular mechanism that may play a general role in animals' ability to respond appropriately when starved.
In research that may have implications for studying eating disorders in humans, a worm the size of a pinhead is helping researchers at UT Southwestern Medical Center unravel the mechanisms of hunger.
Within a hormone-triggered cascade of molecular signals that plays a crucial for a wide range of physiological functions, researchers for the very first time have identified a protein that functions specifically to extend lifespan and youthfulness - without disrupting fertility
New research at UT Southwestern Medical Center shows that on a biochemical level, hormone-like molecules in tiny worms called nematodes work similarly to the way in which certain hormones work in humans - findings that one day may help eradicate worm infections that afflict a third of the world's population.
Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans).
In an effort to understand the molecular mechanisms that control aging, Howard Hughes Medical Institute researchers and their colleagues have now uncovered 10 new genes that regulate longevity in yeast. The studies also suggest a new model for how aging is slowed when caloric intake is restricted.
The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.
University of Utah biologists found a gene that controls rhythmic events in a worm's life: swallowing food, laying eggs and pooping.
Researchers at Duke University Medical Center have identified a previously unknown family of virulence factors that make the bacterium responsible for the plague especially efficient at killing its host.
A team of genomic researchers headed by biologists at New York University's Center for Comparative Functional Genomics, in collaboration with researchers at Harvard University, the Max Planck Institute, and Cenix Biosciences, has mapped out a preliminary molecular diagram of the early stages of embryo formation, offering for the first time a global look at how a single cell begins its path into a multi-cellular organism.
A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.
According to U.S. scientists how well you respond to stress predicts how long you will live, at least if you are a worm.
Researchers have identified 23 new longevity genes by screening the genome of Caenorhabditis elegans, a small worm that is used as a model organism in genetics studies. The findings are reported in the inaugural issue of PLoS Genetics.
The findings also may lead to an improved understanding of a disorder called early-onset torsion dystonia.
Researchers at New York University and the medical schools at Harvard and Yale universities have identified new genes necessary for embryonic development, according to findings published in the latest issue of Genome Research.