Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
Ancient philosophers looked to alchemy for clues to life everlasting. Today, researchers look to their yeast.
Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.
Opening up a can of worms is a good way to start hunting for new drugs, recommend researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine.
In our youth we are strong and healthy and then we weaken and die - that's probably how most would describe what ageing is all about. But, in nature, the phenomenon of ageing shows an unexpected diversity of patterns and is altogether rather strange, conclude researchers from The University of Southern Denmark.
Researchers at the Stanford University School of Medicine have discovered that males of the laboratory roundworm secrete signaling molecules that significantly shorten the lifespan of the opposite sex.
Vitamin supplements are a billion-dollar industry. We want to stay healthy and fit and help our bodies with this. But perhaps we are achieving precisely the opposite?
A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.
One might wonder why researchers would even care about the nuances of the one-millimeter long nematode worm, let alone take the time to study them. But the answer is simple: they can provide powerful insights into human health and disease.
Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.
Who would not want to live a long and healthy life? A freely available food supplement could help in this respect, scientists from ETH Zurich have demonstrated in roundworms. Vitamin B3 - also known as niacin - and its metabolite nicotinamide in the worms' diet caused them to live for about one tenth longer than usual.
A major aim of today's neuroscience is to understand how an organism's nervous system processes sensory input and generates behavior. To achieve this goal, scientists must obtain detailed maps of how the nerve cells are wired up in the brain, as well as information on how these networks interact in real time.
Biologists at the University of Fribourg have been looking at a threadworm gene which also occurs in humans. This gene could be central to a genetic system which is responsible for development, reproduction and the ageing process.
The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants to map those networks, creating a wiring diagram of the brain that could help scientists learn how we each become our unique selves.
Six graduate students and one undergraduate were named as recipients of Genetics Society of America poster awards at the 19th International C. elegans Meeting, held June 26 on the campus of the University of California, Los Angeles.
The idea that worms can be seen as waveforms allowed scientists at Rice University to find new links in gene networks that control movement.
Mathematicians from Queen Mary, University of London will bring researchers one-step closer to understanding how the structure of the brain relates to its function in two recently published studies.
Researchers in the group of Ralf Sommer at the Max Planck Institute for Developmental Biology in Tuebingen, Germany, have for the first time been able to identify neuronal correlates of behaviour by comparing maps of synaptic connectivity, or "connectomes", between two species with different behaviour.
The gonad is well known to be important for reproduction but also affects animal life span. Removal of germ cells - the sperm and egg producing cells - increases longevity of the roundworm Caenorhabditis elegans. However, the underlying molecular mechanisms were a mystery. Now scientists at the Cologne-based Max Planck Institute for Biology of Ageing, have discovered that germ cell removal flips a "molecular switch" that extends the life span by using components of a "developmental clock".
Listed below are the selected highlights for the December 2012 issue of the Genetics Society of America's journal, Genetics.
In the quest to understand how the brain turns sensory input into behavior, Harvard scientists have crossed a major threshold. Using precisely-targeted lasers, researchers have been able to take over an animal's brain, instruct it to turn in any direction they choose, and even to implant false sensory information, fooling the animal into thinking food was nearby.