Calcium News and Research

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Calcium, the most abundant mineral in the body, is found in some foods, added to others, available as a dietary supplement, and present in some medicines (such as antacids). Calcium is required for muscle contraction, blood vessel expansion and contraction, secretion of hormones and enzymes, and transmitting impulses throughout the nervous system. The body strives to maintain constant concentrations of calcium in blood, muscle, and intercellular fluids, though less than <1% of total body calcium is needed to support these functions.

The remaining 99% of the body's calcium supply is stored in the bones and teeth where it supports their structure. Bone itself undergoes continuous remodeling, with constant resorption and deposition of calcium into new bone. The balance between bone resorption and deposition changes with age. Bone formation exceeds resorption in growing children, whereas in early and middle adulthood both processes are relatively equal. In aging adults, particularly among postmenopausal women, bone breakdown exceeds formation, resulting in bone loss that increases the risk of osteoporosis over time.

microRNA may influence development of alcohol tolerance

In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species.

30 Jul 2008

Oily fish protect Japanese men against clogged arteries

If you're fishing for ways to reduce the risk of heart disease, you might start with the seafood-rich diet typically served up in Japan. According to new research, a lifetime of eating tuna, sardines, salmon and other fish appears to protect Japanese men against clogged arteries, despite other cardiovascular risk factors.

28 Jul 2008

Accelerated bone turnover remains after weight loss

When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones.

28 Jul 2008

Knowing means simplifying: gluten-free diet alone is enough to cure the bones of pediatric patients with celiac disease

Individuals affected by celiac disease (gluten intolerance) often present an altered calcium (Ca2+) metabolism that can cause osteopenia, a bone mass decrease due to the impaired adsorption of this mineral, which can lead to osteoporosis (in 35-85% of the cases).

27 Jul 2008

Researchers find key mechanism of cell damage in aging and disease

Researchers have taken a first snapshot of how a class of highly reactive molecules inflicts cellular damage as part of aging, heart disease, stroke, cancer, diabetes, kidney disease and Alzheimer's disease to name a few. According to a study published today in the journal Cell, researchers have discovered a tool that can monitor related damage and determine the degree to which antioxidant drugs effectively combat disease.

24 Jul 2008

Tethered bilayer membrane may unlock secrets of early-stage Alzheimer's

Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer's disease actually impairs a neuron's structure and function.

23 Jul 2008

Controlling plaque without toothpaste

Leeds Dental Institute, ranked the top school in the UK for dentistry is currently looking at new and better ways to improve dental treatment and take the fear factor out of the patient experience for good.

23 Jul 2008

Radical new technology could end drilling and filling misery at the dentist

Radical new dental technology could mean the end of the drilling and filling misery many endure at the dentists.

22 Jul 2008

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases

Researchers at Fred Hutchinson Cancer Research Center have received a $7.6 million, four-year grant from the National Human Genome Research Institute to better understand the genetic and biological roots of common diseases. The Hutchinson Center is one of four U.S. research institutes to receive grants totaling about $31 million toward this effort.

17 Jul 2008

Turning on hormone tap could aid osteoporosis fight

A potential new drug that 'opens the taps' for the release of useful hormones could stimulate new bone growth - and may eventually bring relief to osteoporosis sufferers.

From The University of Manchester 16 Jul 2008

Prehypertension in adults aged 18 to 30 common and associated with coronary atherosclerosis

Prehypertension during young adulthood is common and is associated with subsequent coronary atherosclerosis, according to a study published in today's issue of Annals of Internal Medicine.

14 Jul 2008

Only 11% of children's food products provide good nutritional quality

Nine out of ten regular food items aimed specifically at children have a poor nutritional content - because of high levels of sugar, fat or sodium - according to a detailed study of 367 products published in the July issue of the UK-based journal Obesity Reviews.

14 Jul 2008

Increased potassium/sodium in diet may decrease risk of hypertension, coronary heart disease and stroke

A new article indicates that an increased intake in minerals such as potassium, and possibly magnesium and calcium by dietary means may reduce the risk of high blood pressure and decrease blood pressure in people with hypertension. A high intake of these minerals in the diet may also reduce the risk of coronary heart disease and stroke.

8 Jul 2008

Controlling bone disease improves survival of hemodialysis patients

Consistently maintaining certain blood levels of markers of bone metabolism and disease can prolong the lives of patients on hemodialysis, according to a study appearing in the September 2008 issue of the Clinical Journal of the American Society Nephrology (CJASN).

3 Jul 2008

Coronary arterial calcium scans help detect overall death risk in the elderly

Measuring calcium deposits in the heart's arteries can help predict overall death risk in American adults, even when they are elderly, according to a new study published in the July issue of Journal of the American College of Cardiology.

2 Jul 2008

New discovery a step towards better diabetes treatment

In the July 2nd issue of the prestigious journal Cell Metabolism Uppsala scientists are presenting new findings that shed light on the processes that determine the release of the blood sugar-lowering hormone insulin.

1 Jul 2008

Carbohydrate and caffeine following exhaustive exercise helps muscles refuel

Recipe to recover more quickly from exercise: Finish workout, eat pasta, and wash down with five or six cups of strong coffee.

1 Jul 2008

Neuroscientists pinpoint how neural activity boosts blood flow to the brain

New research from Harvard University neuroscientists has pinpointed exactly how neural activity boosts blood flow to the brain. The finding has important implications for our understanding of common brain imaging techniques such as fMRI, which uses blood flow in the brain as a proxy for neural activity.

26 Jun 2008

Gastric bypass linked to greater risk of kidney stones

Morbidly obese patients who undergo a particular type of gastric bypass surgery called Roux-en-Y gastric bypass (RYGB) are at an increased risk of developing kidney stones - small, pebble-like deposits that can result in severe pain and require an operation to remove them - earlier than previously thought. These stones develop in patients within only a few months following the procedure rather than several months to years, according to research published in the June issue of the Journal of the American College of Surgeons.

26 Jun 2008

Clinical Data secures European patent for key multi-drug resistance gene

Clinical Data, Inc. has announced that the European Patent Office has granted Patent No. 1232260 to Bernried, Germany-based Epidauros Biotechnologie AG, a wholly-owned subsidiary of Clinical Data, relating to the use of a genetic variant, or biomarker, of the gene MDR1 (also known as ABCB1), which encodes P-glycoprotein (PGP).

26 Jun 2008