Cancer diagnostics News and Research

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Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.

24 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

$Multiple fractionation approach for measuring cancer biomarker enrichment in exosomes$

Multiple fractionation approach for measuring cancer biomarker enrichment in exosomes

Postnova Analytics reports that researchers from the University of Utah have used a novel combination of Asymmetrical Flow Field-Flow Fractionation and Centrifugal Field-Flow Fractionation to measure cancer biomarker enrichment in exosomes.

From Postnova Analytics 27 Nov 2020

Measurement of Cancer Biomarker Enrichment in Exosomes

Postnova Analytics reports that researchers from the University of Utah (Salt Lake City, USA) have used a novel combination of Asymmetrical Flow Field-Flow Fractionation and Centrifugal Field-Flow Fractionation to measure cancer biomarker enrichment in exosomes.

From Postnova Analytics 24 Nov 2020

A new method to improve the preclinical evaluation of CAR T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies, in which the immune system's T cells are extracted from a patient, engineered to target a specific tumor-associated molecule and then grown and reinfused for cancer treatment.

6 Nov 2020

Fecal immunochemical test accurately rules out bowel cancer in patients with suspicious symptoms

Findings from the largest international research study found that using FIT is almost 100% accurate at ruling out bowel cancer in patients with suspicious symptoms.

23 Oct 2020

New lab-on-a-chip can help study tumor heterogeneity, improve cancer therapies

Electrical engineers, computer scientists and biomedical engineers at the University of California, Irvine have created a new lab-on-a-chip that can help study tumor heterogeneity to reduce resistance to cancer therapies.

8 Oct 2020

Ludwig study uncovers a nutritional approach to improve cancer immunotherapy

A Ludwig Cancer Research study has uncovered a mechanism by which the tumor's harsh internal environment sabotages T lymphocytes, leading cellular agents of the anticancer immune response.

5 Oct 2020

NCCN's first patient and caregiver resource focused on childhood leukemia

The National Comprehensive Cancer Network today announced the publication of the organization's first patient and caregiver resource focused on a childhood cancer type.

23 Sep 2020

Black women experience longer waits for treatment after breast cancer diagnosis, indicates study

New research suggests that Black women experience longer waits for treatment initiation than white women after a breast cancer diagnosis, and their duration of treatment is prolonged.

21 Sep 2020

Hannover and Rostock team up to develop non-invasive optical melanoma diagnostics

Leibniz University Hannover and Rostock University Medical Center receive funding for the development of non-invasive optical melanoma diagnostics.

17 Sep 2020

Combined use of three drugs linked with lower lung cancer incidence and mortality

Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology.

17 Sep 2020

First clinical trial launched to test psilocybin therapy for depression in cancer patients

The first clinical trial to test the safety and feasibility of psilocybin therapy with simultaneous administration and one-on-one patient support to treat depression in cancer patients was launched today by Maryland Oncology Hematology at the Aquilino Cancer Center at Adventist HealthCare Shady Grove Medical Center.

16 Sep 2020

Breakthrough discovery could turn cancer into a treatable disease

Professor Michael Lisanti and Professor Federica Sotgia have made a discovery that could turn cancer into a treatable disease and remove the fear from a cancer diagnosis.

16 Sep 2020

New, rapid test detects ovarian cancer more accurately

The CA125 antigen, a plasma membrane glycoprotein found in the tissues of the female reproductive tract, is commonly used for the detection of ovarian cancer but works poorly on its own in identifying early stage cancers.

11 Sep 2020

COVID-19 caused substantial disruptions to essential health services in most countries

The COVID-19 pandemic caused substantial disruptions in essential health services in 9 out of 10 countries surveyed by WHO.

7 Sep 2020

Researchers develop new model to predict survival in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer among women and men in the USA, and recent studies have shown an increasing incidence in less developed regions, including Sub-Saharan Africa (SSA).

3 Sep 2020

Major UK study launched to assess the impact of COVID-19 on cancer patients

A new UK study has been launched to assess the impact of covid-19 on people with cancer.

2 Sep 2020

Caring for newly diagnosed dementia patients associated with increase in depressive symptoms

Caring for a partner or spouse with a new diagnosis of Alzheimer's or related dementia is associated with a 30% increase in depressive symptoms, compared to older adults who don't have a spouse with dementia--and these symptoms are sustained over time, a new University of Michigan study found.