Candida Albicans News and Research

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Reducing length of antibiotic course decreases risk of drug resistance

Treatments using antibiotics should stop as soon as possible to prevent patients passing the "tipping point" of becoming resistant to their effects, new research has shown.

10 Jul 2018

Scientists sequence and analyze genomes of Candida albicans

Candida albicans is one of the most formidable fungal species, causing infection in humans. Investigating the structure and reproduction methods of pathogenic populations can help us to understand how they emerge and spread.

10 Jul 2018

Bacteria enhance antifungal drug resistance in early childhood caries

Early childhood caries, a form of severe tooth decay affecting toddlers and preschoolers, can set children up for a lifetime of dental and health problems. The problem can be significant enough that surgery is the only effective way to treat it.

25 Apr 2018

NovaDigm Therapeutics initiates NDV-3A Phase 2a study for reduction of S. aureus in military trainees

NovaDigm Therapeutics, a company developing innovative immuno-therapeutics and preventative vaccines for fungal and bacterial infections, today announced the initiation of a Phase 2a study evaluating NDV-3A for the reduction of Staphylococcus aureus (S. aureus) colonization in a high-risk population of military trainees.

19 Apr 2018

Microscopic revelations could lead to new treatment options for deadly blood infections

Researchers at the University of Calgary's Cumming School of Medicine (CSM) have for the first time been able to observe -- live and in real-time -- how the human body responds to often lethal fungal blood infections in the lung.

4 Apr 2018

New gene drive approach helps pinpoint combination therapies against fungal pathogens

Candida albicans is a notorious human fungal pathogen that causes thrush and serious systemic infections. Opportunistic C. albicans fungi, which often live inconspicuously in the normal flora of human skin and gut, can switch from their harmless stealth mode to become aggressive pathogens, especially in people whose immune systems are already compromised by pre-existing diseases or harsh drug therapies.

30 Oct 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

Multi-drug resistant fungi found in UK hospitals - alarms health officials

Latest reports have confirmed that over 200 patients in England have been infected with a drug-resistant fungus called Candida auris that was first detected in Japan. High alerts have been put in place to look out for further infections and prevent spread.

15 Aug 2017

Salford scientists may have found simple way for designing new antibiotics

CANCER researchers in the UK may have stumbled across a solution to reverse antibiotic drug resistance and stop infections like MRSA.

12 Jul 2017

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

11 Jul 2017

Penn study points to novel therapeutic strategy for preventing severe tooth decay in toddlers

Though most tooth decay can be blamed on bacteria, such as Streptococcus mutans, the fungus Candida albicans may be a joint culprit in an alarmingly common form of severe tooth decay affecting toddlers known as early childhood caries.

20 Jun 2017

Scientists discover new approach for antifungal drug treatments

Each year, invasive fungal infections sicken an estimated 2 million people worldwide and kill nearly 800,000 - but a team of international scientists have discovered a new approach for antifungal drug treatments.

15 Jun 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

In a small pilot study of men with schizophrenia, researchers at Johns Hopkins Medicine and Sheppard Pratt Health System say they have evidence that adding probiotics -- microorganisms, such as bacteria found in yogurts -- to the patients' diets may help treat yeast infections and ease bowel problems.

5 Apr 2017

Scientists develop new method of care to maintain speech in throat cancer patients

Through the work of the School of Biosciences team, in collaboration with East Kent Hospitals University NHS Foundation Trust, Kent has developed a new method of care for patients who have to have their larynx removed.

29 Nov 2016

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power.

17 Nov 2016

New biological mechanism generates cells to fight against Candida albicans infections, find researchers

Researchers from the Universitat de València and the Cedar Sinai Medical Center in Los Angeles have partnered to describe a biological mechanism that generates cells which are better equipped to fight off serious infections caused by the Candida albicansfungus.

26 Oct 2016

Fungal communities in chronic wounds can be linked to poor outcomes and slow healing

Researchers in Pennsylvania and Iowa have discovered that fungal communities found in chronic wounds can form mixed bacterial-fungal biofilms and can be associated with poor outcomes and longer healing times.

6 Sep 2016

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.

11 Aug 2016

Researchers design inhibitory peptide to unleash defence mechanisms against fungal pathogens

For most people, a simple case of thrush or athlete's foot can be quickly and easily treated using over-the-counter anti-fungal creams and pills.

19 Jul 2016