Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Researchers investigated the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma.

31 Jul 2023

Reinforcement learning improves performance of AI-based skin cancer diagnosis

Artificial intelligence (AI) is already being used to diagnose skin cancer, but it cannot (yet) keep pace with the complex decision-making of doctors in practice.

28 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

Healthy breast fat may protect against invasive breast cancer

Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer.

17 Jul 2023

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome that increases the risk of kidney cancer.

13 Jul 2023

Cetuximab plus radiotherapy effective in treating locally advanced cutaneous squamous cell cancer

A new research paper was published in Oncotarget's Volume 14 on July 7, 2023, entitled, "Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series."

12 Jul 2023

Study uncovers three previously unknown membrane proteins in ovarian cancer

A study led by Nagoya University in Japan has identified three previously unknown membrane proteins in ovarian cancer.

7 Jul 2023

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal and the Jewish General Hospital (JGH) has found fecal microbiota transplants (FMT) from healthy donors are safe and show promise in improving response to immunotherapy in patients with advanced melanoma.

7 Jul 2023

Researchers show how communication networks in the tumor microenvironment promote cancer growth

Tumors consist of both the actual, malignant cancer cells and healthy, non-transformed cells in the immediate environment.

7 Jul 2023

Single-cell RNA sequencing provides new insights into gastric cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

6 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

A healthy lifestyle reduces risk of developing severe liver disease

Researchers investigate the correlation between a healthy lifestyle and Life’s Essential 8 scores in new-onset severe non-alcoholic fatty liver disease.

29 Jun 2023

GREB1 gene key to liver cancer development, study finds

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.

27 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

24 Jun 2023

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Dr. Niklas Klümper, resident at the Department of Urology and Pediatric Urology of the University Hospital Bonn (UKB) and working group leader at the Institute for Experimental Oncology (IEO), and Dr. Jonas Saal, resident at the Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology of the UKB, demonstrated a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.

22 Jun 2023

Carcinoma News and Research

Further Reading

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Reinforcement learning improves performance of AI-based skin cancer diagnosis

Tumor-derived GDF-15 suppresses immunotherapy response

Six new Damon Runyon Clinical Investigators announced for 2023

Study sheds light on how viruses override host cell's DNA replication machinery

Healthy breast fat may protect against invasive breast cancer

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Cetuximab plus radiotherapy effective in treating locally advanced cutaneous squamous cell cancer

Study uncovers three previously unknown membrane proteins in ovarian cancer

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

Researchers show how communication networks in the tumor microenvironment promote cancer growth

Single-cell RNA sequencing provides new insights into gastric cancer

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Spanish researchers develop new immunotherapy combination for liver cancer

A healthy lifestyle reduces risk of developing severe liver disease

GREB1 gene key to liver cancer development, study finds

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Breakthrough discovery could lead to new treatments for brain metastases

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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