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Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

In a collaborative project involving scientists from three continents, researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer.

20 Jan 2011

MacroGenics commences MGAH22 Phase I trail for patients with HER2-positive cancer

MacroGenics, a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, today announced that it had administered drug to the first cohort of patients in a Phase I clinical trial of MGAH22.

6 Jan 2011

Fraunhofer MEVIS initiates research partnership with ARTORG Center

In a research partnership between the Fraunhofer Institute for Medical Image Computing MEVIS in Bremen and the ARTORG Center for Biomedical Engineering Research at the University of Bern, this navigation technique will be intensively evaluated and developed further at the Eastern Hepatobiliary Surgery Hospital in Shanghai.

23 Dec 2010

Presence of CTCs may predict disease recurrence in patients with neck and head cancer

A new study suggests that the presence of tumor cells in the circulating blood of patients with squamous cell cancer of the head and neck may predict disease recurrence and reduced survival.

21 Dec 2010

Robotic surgery as effective as other minimally invasive techniques for head and neck squamous cell carcinomas

Less-invasive robotic surgery for upper airway and digestive track malignant tumors is as effective as other minimally invasive surgical techniques based on patient function and survival, according to University of Alabama at Birmingham researchers.

21 Dec 2010

Genetic breakthrough in lung cancer

For the study the team studied samples of lung tumors and nearby healthy lung tissue from 30 patients and examined the samples for the presence of messenger ribonucleic acid (mRNA) associated with 48 known genes for molecules called nuclear hormone receptors. Then they compared the active genes with patient outcomes and found that the expression of genes for certain nuclear hormone receptors helped predict patient survival.

16 Dec 2010

Liver cancer in cirrhotic patients effectively treated with radiofrequency ablation

Researchers from Italy determined that radiofrequency ablation (RFA) is a safe and effective therapy for managing hepatocellular carcinoma (HCC) in cirrhotic patients. The high repeatability of RFA is advantageous in controlling recurrences of cancerous tumors in the liver. Results of this 10-year retrospective study are available in the January 2011 issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

16 Dec 2010

Arthritis drug reduces incidence of non-melanoma skin cancers

A widely-used arthritis drug reduces the incidence of non-melanoma skin cancers - the most common cancers in humans - according to a study published this week in the Journal of the National Cancer Institute. The COX-2 inhibitor celecoxib (brand name Celebrex), which is currently approved for the treatment of osteoarthritis, rheumatoid arthritis and acute pain in adults led to a 62 percent reduction in non-melanoma skin cancers, which includes basal cell carcinomas and squamous cell carcinomas.

3 Dec 2010

NSAID Celebrex may help prevent non-melanoma skin cancer development: Research

New research shows the NSAID Celebrex may help prevent some non-melanoma skin cancers from developing in patients who have pre-cancerous actinic keratoses lesions and are at high risk for having the disease.

30 Nov 2010

Researcher develops new method that causes cancer cells to self-destruct

Tulane University researcher W T. Godbey has developed a treatment for cancer using a method that causes cancer cells to self-destruct while sparing surrounding healthy cells.

23 Nov 2010

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

Exelixis, Inc. today reported interim data from the cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with XL184 in an ongoing phase 2 adaptive randomized discontinuation trial (RDT).

18 Nov 2010

Study shows patient-specific factors delay skin cancer treatment

If detected early, nonmelanoma skin cancers (primarily basal cell and squamous cell carcinomas, the two most common forms of skin cancer) can be easily treated. But when left untreated, these skin cancers can grow and even spread, causing considerably more harm than if they were treated upon initial detection. Now, a new study finds that denial is the top reason why patients delay seeking treatment for skin cancer and shows that this delay results in larger, more serious, skin cancers.

15 Nov 2010

Denial is top reason for patients to delay treatment for skin cancer

12 Nov 2010

Colonoscopy screening could prevent bowel cancer in nearly 99 000 German patients

By the end of this year, colonoscopy screening will have prevented bowel cancer in approximately 99 000 people since it was introduced in Germany. This is the result obtained by Hermann Brenner of the German Cancer Research Center in Heidelberg and his co-authors in their interim assessment conducted eight years after the procedure was added to the German cancer screening program.

11 Nov 2010

Research on immune system may help develop improved vaccines for cancer

Researchers at the University of Cambridge hope to revolutionise cancer therapy after discovering one of the reasons why many previous attempts to harness the immune system to treat cancerous tumours have failed.

8 Nov 2010

Mechanism that controls embryonic development could also prevent cancer

Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth.

29 Oct 2010

New annual campaign to prevent skin cancer

The annual "Euromelanoma Day" campaign is designed to prevent skin cancer among the general public. While there has been considerable interest, it has proved difficult to reach out to some of the at-risk groups. As such, new ways of encouraging these people to go to a dermatologist are being introduced, reveals research from the University of Gothenburg presented at the dermatologist conference in Sweden.

25 Oct 2010

Study: p63 gene stifles spread of cancer

Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center report in the Oct. 21 issue of Nature.

21 Oct 2010

ARID1A gene links ovarian cancer to endometriosis

Researchers with the Ovarian Cancer Research Program of BC (OvCaRe) reveal a major new cancer gene-ARID1A. Mutations are frequent in this gene and link two types of ovarian cancer to endometriosis.

9 Sep 2010

FDA declines to grant Levulan PDT Orphan Designation: DUSA Pharmaceuticals

DUSA Pharmaceuticals, Inc. reported today that on the afternoon of August 5, 2010 the U.S. Food and Drug Administration notified DUSA that it has not granted Orphan Drug Designation for the use of Levulan (aminolevulinic acid HCl) Photodynamic Therapy for the prevention of cutaneous squamous cell carcinomas in patients who have a proven history of multiple localized cutaneous SCCs over a 12 month period.

7 Aug 2010