Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

BioMimetic Therapeutics reports net loss of $7.7M for second-quarter 2010

BioMimetic Therapeutics, Inc. today reported its financial results as of and for the three and six months ended June 30, 2010. For the three months ended June 30, 2010, the Company reported a net loss of $7.7 million, or $0.35 per diluted share, compared to a net loss of $6.3 million, or $0.32 per diluted share, for the same period in 2009. For the six months ended June 30, 2010, the Company reported a net loss of $16.2 million, or $0.73 per diluted share, compared to a net loss of $14.3 million, or $0.75 per diluted share, for the same period in 2009.

6 Aug 2010

Study identifies options for restoring knee cartilage lubrication to prevent OA

An injury to the anterior cruciate ligament is fairly common, especially among young athletes. While it can often be corrected through surgery, the injury can lead to increased risk of developing degenerative joint diseases, including osteoarthritis. The problem is that fluid in the knee joint, which lubricates the cartilage, is impacted by the trauma of the injury and begins to deteriorate.

6 Aug 2010

Mental-health treatment could reduce pain in osteoarthritis patients: Study

How much pain osteoarthritis sufferers feel is directly related to their mental health, a new study by researchers at UC Davis School of Medicine has found. In the study, people with better mental health felt less pain, and people with worse mental health felt more.

31 Jul 2010

Research findings provide new insight into skeletal development

Too little of a protein called neogenin results in a smaller skeleton during development and sets the stage for a more fragile bone framework lifelong, Medical College of Georgia researchers report.

28 Jul 2010

BioMimetic Therapeutics closes underwritten public offering

BioMimetic Therapeutics, Inc., announced today the closing of its previously announced underwritten public offering. Prior to closing, the underwriters exercised their option to purchase an additional approximately 642,000 shares of common stock. As a result, BioMimetic sold a total of approximately 5.64 million shares of its common stock at a price to the public of $8.50 per share.

21 Jul 2010

Athletes who undergo tissue transplant surgery for knee damage can return to sports: Study

Athletes with bone and cartilage knee damage who are treated with transplanted tissue can return to sports after surgery, according to a Hospital for Special Surgery study reported at the annual meeting of the American Orthopaedic Society for Sports Medicine, held July 15-18 in Providence, Rhode Island. The study (abstract 8970) overturns the widely held belief that patients who undergo this surgery do not return to athletics.

20 Jul 2010

Rice University bioengineers win $1.7M NIH grant for cartilage-regeneration research

Bioengineers from Rice University's BioScience Research Collaborative have won a $1.7 million grant from the National Institutes of Health to develop an injectable mix of polymers and adult stem cells that can spur the growth of new cartilage in injured knees and other joints.

20 Jul 2010

ZIOPHARM Oncology commences palifosfamide Phase III clinical trial for metastatic soft tissue sarcoma

ZIOPHARM Oncology, Inc. today announced the initiation of the pivotal Phase III clinical trial for palifosfamide in patients with front-line metastatic soft tissue sarcoma. The study, called PICASSO 3, is an international, randomized, double-blinded, placebo-controlled trial designed to enroll approximately 424 patients with metastatic soft tissue sarcoma who have never been treated with chemotherapy for metastatic disease.

20 Jul 2010

Arthroscopic hip surgery may help athletes resume their sport back: Study

Hip problems can sideline even the best athletes, but a new study led by orthopedic experts from Rush University Medical Center indicates that the use of minimally invasive arthroscopic surgery to treat painful disorders of the hip may give athletes who undergo the procedure another opportunity to resume their sport back at their pre-injury level of competition.

20 Jul 2010

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

Athletes who undergo arthroscopic surgery for a mechanical disorder of the hip have a good chance of being able to return to their sport at a high level of competition, according to a study that will be presented at the annual meeting of the American Orthopaedic Society for Sports Medicine, held July 15-18 in Providence, R.I. Almost 80 percent of patients were able to return to play after hip arthroscopy at an average of 9.4 months after surgery, and roughly 90 percent were able to return to the same level of competition.

16 Jul 2010

New biological scaffolds will provide off-the-shelf tissue transplants

Professor John Fisher from The University of Leeds is speaking today (14 July) at the UK National Stem Cell Network Annual Science Meeting in Nottingham about his team's research into how biological scaffolding will pave the way for off- the-shelf tissue transplants.

14 Jul 2010

BioMimetic announces common stock public offering

BioMimetic Therapeutics, Inc. announced today a public offering of 5,000,000 shares of its common stock. BioMimetic has granted the underwriters an option to purchase up to an additional 15% of shares of common stock to cover over-allotments. BioMimetic expects to use the net proceeds of the offering for development and commercialization of its product pipeline and general corporate purposes.

13 Jul 2010

Amniocentesis and non-embryonic stem cells among list of "Huge Medical Breakthroughs"

Two key focus areas of Biocell Center, the nation's first amniotic fluid stem cell bank, have been recently mentioned among the most important medical discoveries of the last century. Amniocentesis and non-embryonic stem cells were among the list of "Huge Medical Breakthroughs" presented in an article by Althea Chang on Mainstreet.com, produced by TheStreet.com on June 29, 2010.

8 Jul 2010

BioMimetic reports final study results comparing Augment Bone Graft to autograft in foot, ankle fusion surgery

BioMimetic Therapeutics will report today the final, one year results of its North American Pivotal Study comparing Augment Bone Graft to autograft in foot and ankle fusion surgery. The presentation of the data by Dr. Timothy Daniels, associate professor of orthopedic surgery at the University of Toronto and St. Michaels Hospital, will take place at the American Orthopaedic Foot and Ankle Society (AOFAS) summer meeting.

8 Jul 2010

Review examines surgical and non-surgical treatments available for patients with knee arthritis

Middle-aged men and women with osteoarthritis of the knee now have more options than ever before for treatments that may allow them to remain active in the sports they love, according to a review published in the July 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons.

8 Jul 2010

Scientists demonstrate how neural stem cells, precursor cells control growth of glioblastomas

In their latest research, scientists of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, Germany, have demonstrated how the brain's own stem cells and precursor cells control the growth of glioblastomas. Of all brain tumors, glioblastomas are among the most common and most aggressive.

7 Jul 2010

Biomimetic Therapeutics to discuss Augment Bone Graft data results at AOFAS meeting

BioMimetic Therapeutics, Inc. today announced its schedule of events at the American Orthopaedic Foot and Ankle Society (AOFAS) summer meeting being held at the Gaylord National Hotel and Convention Center in National Harbor, Maryland from July 7 - 10, 2010.

2 Jul 2010

Advancements in total hip replacement procedure make young patients opt for surgery

Traditionally, total hip replacement surgery was performed on the elderly, but these days, advancements in the procedure have patients opting for the surgery much earlier in life.

1 Jul 2010

Study implicates cytokine molecule IL-17 in low back pain associated with herniated discs

An immune cell known to cause chronic inflammation in autoimmune disorders has been identified as a possible culprit in low back pain associated with herniated discs, according to doctors at Duke University Medical Center.

29 Jun 2010

Meniscal, cruciate ligament lesions increase risk of knee osteoarthritis

Arthroscopic surgical repair of torn anterior cruciate ligaments (ACL) or meniscal cartilage injuries in the knee does not decrease the chances of developing osteoarthritis, according to a new study published in the online edition and August print issue of the journal Radiology.

29 Jun 2010

Cartilage News and Research

Further Reading

BioMimetic Therapeutics reports net loss of $7.7M for second-quarter 2010

Study identifies options for restoring knee cartilage lubrication to prevent OA

Mental-health treatment could reduce pain in osteoarthritis patients: Study

Research findings provide new insight into skeletal development

BioMimetic Therapeutics closes underwritten public offering

Athletes who undergo tissue transplant surgery for knee damage can return to sports: Study

Rice University bioengineers win $1.7M NIH grant for cartilage-regeneration research

ZIOPHARM Oncology commences palifosfamide Phase III clinical trial for metastatic soft tissue sarcoma

Arthroscopic hip surgery may help athletes resume their sport back: Study

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

New biological scaffolds will provide off-the-shelf tissue transplants

BioMimetic announces common stock public offering

Amniocentesis and non-embryonic stem cells among list of "Huge Medical Breakthroughs"

BioMimetic reports final study results comparing Augment Bone Graft to autograft in foot, ankle fusion surgery

Review examines surgical and non-surgical treatments available for patients with knee arthritis

Scientists demonstrate how neural stem cells, precursor cells control growth of glioblastomas

Biomimetic Therapeutics to discuss Augment Bone Graft data results at AOFAS meeting

Advancements in total hip replacement procedure make young patients opt for surgery

Study implicates cytokine molecule IL-17 in low back pain associated with herniated discs

Meniscal, cruciate ligament lesions increase risk of knee osteoarthritis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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