Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Avila's AVL-292 demonstrates disease-modifying effects in prophylactic, therapeutic models of rheumatoid arthritis

Avila Therapeutics™, Inc., a biotechnology company developing targeted covalent drugs that treat diseases through protein silencing, today announced results of preclinical studies demonstrating that its clinical candidate, AVL-292, potently inhibits B cell receptor signaling, and demonstrates efficacy in a rodent model of rheumatoid arthritis. These new data were presented Saturday, June 26, 2010 at the Federation of Clinical Immunology Societies (FOCIS) 2010 annual meeting in Boston, MA.

29 Jun 2010

Failed ACL surgeries are more common than previously thought

Nick Van Erp, active in soccer since elementary school and lacrosse since junior high, tore the anterior cruciate ligament in his knee during a spring lacrosse game his freshman year of high school. His injury, caused by stepping into a pothole and hyper-extending his knee, required surgical repair, ending his season prematurely and the remainder of his high school sports career.

29 Jun 2010

FDA accepts for review BioMimetic Therapeutics' Augment Bone Graft PMA application

BioMimetic Therapeutics, Inc. today announced the Food & Drug Administration (FDA) has accepted for review its Premarket Approval (PMA) application for Augment™ Bone Graft for use in foot and ankle fusions in the U.S. The FDA has now filed the application and begun the comprehensive review of the clinical module.

29 Jun 2010

Arteriocyte honored as Venture of Year Award Finalist

Arteriocyte, Inc., was honored Friday by the Ohio Venture Association as a Venture of Year Award Finalist. Founded in 2004 to develop proprietary stem cell and tissue engineering based therapies, Arteriocyte focuses on developing commercially available stem cell based therapies using multiple sources of adult derived stem cells (marrow, peripheral cord blood, and cartilage) for delivery to injured tissues in order to speed repair and improve function.

28 Jun 2010

Cartilage loss plays a role in development of OA, study says

A recent study determined that bone area predicted the development of medial (inner side) and lateral (outer side) knee cartilage damage and loss of medial cartilage volume. Subchondral bone mineral density (BMD) was associated with medial defect development but not cartilage loss. Researchers believe subchondral bone changes and loss of cartilage contribute to the development of osteoarthritis (OA).

28 Jun 2010

Kensey Nash announces strategic agreement with Arthrex for ECM technology

Kensey Nash Corporation, a regenerative medicine company, and Arthrex, Inc., a worldwide leader in sports medicine product development and educational services for orthopaedic surgeons, today announced a strategic agreement regarding products developed from Kensey Nash's unique extracellular matrix technology.

24 Jun 2010

Kensey Nash, St. Jude Medical sign two-year Supply Agreement

Kensey Nash Corporation, a regenerative medicine company, today announced that it entered into a new two-year Supply Agreement with St. Jude Medical, Inc. for the period from January 1, 2011 to December 31, 2012. The agreement provides for Kensey Nash to be the exclusive outside supplier of collagen plugs, one of the key resorbable components of the Angio-Seal Vascular Closure Device, the leading arterial puncture closure product in the world.

24 Jun 2010

Spanish scientists propose human amniotic membrane as new tool for repairing damaged articular cartilage

Spanish scientists have proposed using human amniotic membrane as a new tool for repairing damaged human articular cartilage, which heals very poorly because of its low capacity for self-repair. Their research, published in the journal Cell and Tissue Banking, shows that the cellular density of the cartilage synthesised could be greater than that of the body's own natural cartilage.

23 Jun 2010

First implantation of PyroTITAN Humeral Resurfacing Arthroplasty performed outside US in Australia

Ascension Orthopedics, Inc., a market leader in PyroCarbon orthopedic implants, announces the first implantation of the PyroTITAN™ Humeral Resurfacing Arthroplasty outside the United States. The PyroTITAN was implanted last month in Brisbane, Australia in a 46-year-old patient who reported "immediate pain relief" within 24 hours of surgery. The PyroTITAN Humeral Resurfacing implant is the first commercially-available shoulder arthroplasty prosthesis made of PyroCarbon in the world.

17 Jun 2010

VBL presents positive preclinical data on VB-201 for rheumatoid arthritis at EULAR

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced preclinical data demonstrating that VB-201 possesses anti-inflammatory properties and effectively reduced the symptoms of arthritis in experimental models.

17 Jun 2010

Hip strengthening regimen proves effective at reducing PFP in female runners: Study

A twice weekly hip strengthening regimen performed for six weeks proved surprisingly effective at reducing -- and in some cases eliminating -- knee pain referred to as patellofemoral pain in female runners.

5 Jun 2010

RepRegen reports 3-month data from study of StronBone bioactive glass with Strontium

RepRegen™, the 'smart biomaterials' company previously known as BioCeramic Therapeutics, announced today that three-month data from an in vivo study of its StronBone™ bioactive glass with Strontium demonstrated that it can generate bone quality in and around defects that appears by analytical tests to be significantly superior to a standard bone void filler in the control defect.

2 Jun 2010

Low frequency ultrasound can heal and regenerate body tissues

When we think of ultrasound, it's usually imaging the inside of the body that springs to mind. However, while ultrasound imaging typically requires frequencies that are 50 to 2500 times higher than those human ear can detect, recent increasing evidence indicates that ultrasound at lower frequency can also be used to help certain body tissues to heal and regenerate. Now research that appears in Open Access Journal of Tissue Engineering published by SAGE-Hindawi suggests that ultrasound could also help tissue grafts to survive and thrive following surgery.

28 May 2010

Shark cartilage extract shows no benefit for patients with advanced non-small cell lung cancer

In the first scientific study of its kind, shark cartilage extract, AE-941 or Neovastat, has shown no benefit as a therapeutic agent when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

27 May 2010

Kensey Nash granted FDA 510(k) clearance for Meso BioMatrix ECM product

Kensey Nash Corporation, a leading medical technology company that provides innovative resorbable biomaterial technology for a wide range of medical procedures, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration for its second extracellular matrix (ECM) product, the Meso BioMatrix™ product.

27 May 2010

Defect in cellular pathways provides new explanation for earliest stages of craniosynostosis in newborns

University of Rochester Medical Center scientists discovered a defect in cellular pathways that provides a new explanation for the earliest stages of abnormal skull development in newborns, known as craniosynostosis.

26 May 2010

Arthrosurface achieves significant clinical milestone in implant technology

Arthrosurface, Inc., the developer of inlay joint resurfacing systems, announced the achievement of a significant clinical milestone.

25 May 2010

Europe's leading stem cell bank launches innovative service for liposuction market

Cryo-Save today announced the European introduction of Cryo-Lip, a new product that allows the collection, processing and storage of a rich mixture of adult stem cells from liposuction aspirate (fatty tissue that is normally discarded).

24 May 2010

Natural molecule in body counters progression of osteoarthritis: Scientists

An international team of scientists from The Scripps Research Institute in California and the National Research Institute for Child Health and Development in Japan has discovered that a natural molecule in the body counters the progression of osteoarthritis. The findings could one day lead to new therapies for some common diseases of aging.

19 May 2010

Emisphere Technologies first-quarter net loss increases to $18.5 million

Emisphere Technologies, Inc. today announced its financial results for the first quarter 2010.

17 May 2010

Cartilage News and Research

Further Reading

Avila's AVL-292 demonstrates disease-modifying effects in prophylactic, therapeutic models of rheumatoid arthritis

Failed ACL surgeries are more common than previously thought

FDA accepts for review BioMimetic Therapeutics' Augment Bone Graft PMA application

Arteriocyte honored as Venture of Year Award Finalist

Cartilage loss plays a role in development of OA, study says

Kensey Nash announces strategic agreement with Arthrex for ECM technology

Kensey Nash, St. Jude Medical sign two-year Supply Agreement

Spanish scientists propose human amniotic membrane as new tool for repairing damaged articular cartilage

First implantation of PyroTITAN Humeral Resurfacing Arthroplasty performed outside US in Australia

VBL presents positive preclinical data on VB-201 for rheumatoid arthritis at EULAR

Hip strengthening regimen proves effective at reducing PFP in female runners: Study

RepRegen reports 3-month data from study of StronBone bioactive glass with Strontium

Low frequency ultrasound can heal and regenerate body tissues

Shark cartilage extract shows no benefit for patients with advanced non-small cell lung cancer

Kensey Nash granted FDA 510(k) clearance for Meso BioMatrix ECM product

Defect in cellular pathways provides new explanation for earliest stages of craniosynostosis in newborns

Arthrosurface achieves significant clinical milestone in implant technology

Europe's leading stem cell bank launches innovative service for liposuction market

Natural molecule in body counters progression of osteoarthritis: Scientists

Emisphere Technologies first-quarter net loss increases to $18.5 million

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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