Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Researchers discover how the sponginess of stem cell nuclei controls cell differentiation

Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they "differentiate" into specialized cells.

3 Jan 2022

Combination of gallic acid and stretching decreases arthritis inflammation markers in the cells

A healthy diet and a little exercise appear to be good for arthritis, even on the cellular level.

15 Dec 2021

Researchers discover mechanism for congenital disorders of glycosylation

Greenwood Genetic Center researchers are reporting the discovery of a mechanism that contributes to the tissue phenotypes seen in PMM2-CDG, the most common of the congenital disorders of glycosylation (CDGs).

8 Dec 2021

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

You don't have to go far to find ticks. Just step outside and look for some grass. Look to the top of the shiny, green blade – usually ankle high. A tick might be there, waiting.

30 Nov 2021

GPR126 gene may play an essential role in placental development, study reveals

Scientists working with an experimental mouse model at the Centro Nacional de Investigaciones Cardiovasculares have identified the essential role of the gene GPR126 in the development of the placenta during pregnancy.

12 Nov 2021

Global effort focuses on developing better methods to quantify joint damage in rheumatoid arthritis patients

Crowdsourcing has become an increasingly popular way to develop machine learning algorithms to address many clinical problems in a variety of illnesses.

7 Nov 2021

Virtual exercise program can be safe for people with osteoarthritis, research finds

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that a virtual exercise program can be safe for people with musculoskeletal conditions, improved their health outcomes, and helped them feel more socially connected, an important benefit during the pandemic when many people have chosen to avoid in-person exercise classes.

2 Nov 2021

New approach to control the hierarchical assembly of protein pathways with DNA

Northwestern investigators have identified a novel approach to control the hierarchical assembly of protein pathways with DNA, according to a study published the Proceedings of the National Academy of Sciences.

29 Oct 2021

Researchers discover genetic risk variants involved in osteoarthritis

Osteoarthritis is the leading cause of pain and disability worldwide. There is no cure, only pain relief. Patients' joints become inflamed, and they feel creaky and stiff in the morning.

28 Oct 2021

Study explains how stem cells can help lizards regenerate better tails

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube.

15 Oct 2021

$Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities$

Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities

Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now.

8 Oct 2021

Researchers capture mechanisms for predicting cartilage degradation and recovery after ACL injury

Post-traumatic osteoarthritis is a musculoskeletal disorder shadowing especially the life of young and active population.

6 Oct 2021

Southampton researchers invent new way to generate cartilage tissue from stem cells

Researchers at the University of Southampton have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage.

28 Sep 2021

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Our ability to heal and regenerate new tissue after an injury has much to do with biological sex. For instance, following menopause, the loss of sex-hormone signaling in women can lead to degenerative diseases such as osteoporosis and osteoarthritis, where bone and cartilage degrade and become more delicate and brittle because of tissue loss.

21 Sep 2021

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity.

15 Sep 2021

Gut microbiome profile could help predict patient's rheumatoid arthritis prognosis

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic's Center for Individualized Medicine.

14 Sep 2021

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

A research team from the Universitat Autònoma de Barcelona has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio A disease.

12 Sep 2021

Researchers create a QIBA profile for cartilage compositional imaging

New recommendations will help provide more reliable, reproducible results for MRI-based measurements of cartilage degeneration in the knee, helping to slow down disease and prevent progression to irreversible osteoarthritis, according to a special report published in the journal Radiology.

7 Sep 2021

Cultured cartilage cells from the nasal septum could help relieve osteoarthritis in the knee

Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee – according to researchers from the University of Basel and the University Hospital of Basel, they can also withstand the chronic inflammatory tissue environment in osteoarthritis and even counteract the inflammation.

1 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.